MABS422 | Anti-FGF4, clone 2D7D5 Antibody

MABS422
100 µL  
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      Overview

      Replacement Information

      Key Spec Table

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      MFC, ELISAMAscitesMonoclonal Antibody
      Description
      Catalogue NumberMABS422
      DescriptionAnti-FGF4, clone 2D7D5 Antibody
      Alternate Names
      • Fibroblast growth factor 4
      • FGF-4
      • Heparin secretory-transforming protein 1
      • HST
      • HST-1
      • HSTF-1
      • Heparin-binding growth factor 4
      • HBGF-4
      • Transforming protein KS3
      Background InformationFibroblast growth factor 4, also known as FGF-4, Heparin secretory-transforming protein 1, HST, HST-1, HSTF-1, Heparin-binding growth factor 4, HBGF-4, or Transforming protein KS3 and encoded by the gene FGF4/ HST/ HSTF1/ KS3 is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities and are involved in a variety of biological processes including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. FGF4 was identified by its oncogenic transforming activity. FGF4 and FGF3, another oncogenic growth factor, are located closely on chromosome 11. Co-amplification of both genes was found in various kinds of human tumors. Studies on the mouse homolog suggested a function in bone morphogenesis and limb development through the sonic hedgehog (SHH) signaling pathway.
      References
      Product Information
      FormatAscites
      PresentationMouse monoclonal IgG1 ascitic fluid containing up to 0.1% sodium azide.
      Applications
      ApplicationDetect FGF4 using this Anti-FGF4, clone 2D7D5 Antibody validated for use in flow cytometry & ELISA.
      Key Applications
      • Flow Cytometry
      • ELISA
      Application NotesELISA: A representative lot detected control antigen (100 ng) and antigen (10 ng, 50 ng, 100 ng) in ELISA (Direct).
      Biological Information
      ImmunogenPurified recombinant fragment of human FGF4 expressed in E. Coli
      Clone2D7D5
      ConcentrationPlease refer to the Certificate of Analysis for the lot-specific concentration.
      HostMouse
      IsotypeIgG1
      Species Reactivity
      • Mouse
      Antibody TypeMonoclonal Antibody
      Gene Symbol
      • FGF4
      • HST
      • HSTF1
      • KS3
      Purification MethodUnpurified
      UniProt Number
      Molecular Weight22 kDa calculated
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality AssuranceFlow Cytometry Analysis: A 1:200-400 dilution from a representative lot detected FGF4 in NIH/3T3 cells.
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsStable for 1 year at -20°C from date of receipt.
      Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.
      Packaging Information
      Material Size100 µL
      Transport Information
      Supplemental Information
      Specifications