178221 α₂-Antiplasmin, Human Plasma - Calbiochem

A 452-amino acid glycoprotein present in plasma at about 70 µg/ml.

α₂-Antiplasmin, Human Plasma - Calbiochem MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: α₂-Protease Inhibitor, Primary Plasmin Inhibitor

Primary Target: Plasminogen activator-induced lysis of fibrin clots
178221
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      Overview

      Replacement Information

      Key Spec Table

      Pricing & Availability

      Catalogue NumberAvailability Packaging Qty/Pack Price Quantity
      178221-100UG
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          		 Plastic ampoule 100 μg
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          Description
          OverviewA 452-amino acid glycoprotein present in plasma at about 70 µg/ml. Efficiently inhibits the plasminogen activator-induced lysis of fibrin clots. Forms a covalent complex with plasmin and inactivates it.
          Catalogue Number178221
          Brand Family Calbiochem®
          Synonymsα₂-Protease Inhibitor, Primary Plasmin Inhibitor
          References
          ReferencesSchaefer, B.M., et al. 1996. Arch. Dermatol. Res. 288, 122.
          Aoki, N., et al. 1980. Blood 55, 483.
          Saito, H., et al. 1974. Circ. Res. 34, 641.
          Product Information
          Unit of DefinitionOne Inhibitory Unit (I.U.) is defined as the amount of enzyme that will inhibit 1 unit plasmin activity using tosyl-Gly-Pro-Lys-<i>p</i>NA as substrate at 25°C, pH 7.8
          ATP CompetitiveN
          FormSolid
          FormulationLyophilized from 200 mM NaCl, 20 mM Bis-Tris, pH 6.4.
          ReversibleN
          Applications
          Biological Information
          Primary TargetPlasminogen activator-induced lysis of fibrin clots
          Purity≥95% by SDS-PAGE
          SourcePrepared from plasma that has been shown by certified tests to be negative for HBsAg and for antibodies to HIV and HCV.
          Specific Activity≥5 I.U./mg protein
          Physicochemical Information
          Cell permeableN
          Dimensions
          Materials Information
          Toxicological Information
          Safety Information according to GHS
          Safety Information
          Product Usage Statements
          Storage and Shipping Information
          Ship Code Ambient Temperature Only
          Toxicity Standard Handling
          Storage -20°C
          Do not freeze Ok to freeze
          Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
          Packaging Information
          Transport Information
          Supplemental Information
          Specifications

          Documentation

          SDS

          Title

          Safety Data Sheet (SDS) 

          Certificates of Analysis

          TitleLot Number
          178221

          References

          Reference overview
          Schaefer, B.M., et al. 1996. Arch. Dermatol. Res. 288, 122.
          Aoki, N., et al. 1980. Blood 55, 483.
          Saito, H., et al. 1974. Circ. Res. 34, 641.
          Data Sheet

          Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

          Revision02-May-2008 JSW
          Synonymsα₂-Protease Inhibitor, Primary Plasmin Inhibitor
          DescriptionA 452-amino acid glycoprotein present in plasma at about 70 µg/ml. Efficiently inhibits the plasminogen-activator-induced lysis of fibrin clots. Forms a covalent complex with plasmin and inactivates it.
          FormSolid
          FormulationLyophilized from 200 mM NaCl, 20 mM Bis-Tris, pH 6.4.
          SourcePrepared from plasma that has been shown by certified tests to be negative for HBsAg and for antibodies to HIV and HCV.
          Purity≥95% by SDS-PAGE
          Specific activity≥5 I.U./mg protein
          Unit definitionOne Inhibitory Unit (I.U.) is defined as the amount of enzyme that will inhibit 1 unit plasmin activity using tosyl-Gly-Pro-Lys-pNA as substrate at 25°C, pH 7.8
          SolubilityH₂O. Please refer to the vial label for the lot-specific reconstitution volume.
          Storage -20°C
          Do Not Freeze Ok to freeze
          Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
          Toxicity Standard Handling
          ReferencesSchaefer, B.M., et al. 1996. Arch. Dermatol. Res. 288, 122.
          Aoki, N., et al. 1980. Blood 55, 483.
          Saito, H., et al. 1974. Circ. Res. 34, 641.