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MAB6210-KC | Anti-Luteinizing Hormone, clone 090-10226 (1mg) KC

MAB6210-KC
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      Overview

      Replacement Information
      Description
      Catalogue NumberMAB6210-KC
      Brand Family Chemicon®
      Trade Name
      • Chemicon
      DescriptionAnti-Luteinizing Hormone, clone 090-10226 (1mg) KC
      OverviewThis product is intended for use by IVD manufacturers.
      Contact customer service for assistance: oem.reagents@emdmillipore.com
      Alternate Names
      • Anti-Luteinizing Hormone
      References
      Product Information
      FormatPurified
      Control
      • Human pituitary gland
      PresentationPurified immunoglobulin. Liquid in 10 mM sodium phosphate, 150 mM NaCl, pH 7.4 with 0.1% sodium azide
      Applications
      ApplicationAnti-Green Fluorescent Protein Antibody, original GFP only, clone 264-449-2 is an antibody against Green Fluorescent Protein for use in IP, WB & IC.
      Key Applications
      • ELISA
      Application NotesEIA: sensitivity <1 mIU/mL

      Optimal working dilutions must be determined by the end user.
      Biological Information
      ImmunogenHuman pituitary gland
      Clone090-10226
      ConcentrationPlease refer to the Certificate of Analysis for the lot-specific concentration.
      HostMouse
      SpecificityHuman luteinizing hormone. Less than 0.01% cross reactivity to hCG and greater than 0.1% cross reactivity to FSH.

      AFFINITY CONSTANT:

      3.2 x 1010
      IsotypeIgG1
      Species Reactivity
      • Human
      Antibody TypeMonoclonal Antibody
      Entrez Gene Number
      Entrez Gene SummaryThis gene is a member of the glycoprotein hormone beta chain family and encodes the beta subunit of luteinizing hormone (LH). Glycoprotein hormones are heterodimers consisting of a common alpha subunit and an unique beta subunit which confers biological specificity. LH is expressed in the pituitary gland and promotes spermatogenesis and ovulation by stimulating the testes and ovaries to synthesize steroids. The genes for the beta chains of chorionic gonadotropin and for luteinizing hormone are contiguous on chromosome 19q13.3. Mutations in this gene are associated with hypogonadism which is characterized by infertility and pseudohermaphroditism.
      Gene Symbol
      • LHB
      • hLHB
      • LSH-B
      • LH-B
      • LSH-beta
      • CGB4
      Purification MethodAmmonium Sulfate Precipitation
      UniProt Number
      UniProt SummaryFUNCTION: SwissProt: P01229 # Promotes spermatogenesis and ovulation by stimulating the testes and ovaries to synthesize steroids.
      SIZE: 141 amino acids; 15345 Da
      SUBUNIT: Heterodimer of a common alpha chain and a unique beta chain which confers biological specificity to thyrotropin, lutropin, follitropin and gonadotropin.
      SUBCELLULAR LOCATION: Secreted.
      TISSUE SPECIFICITY: Pituitary gland.
      DISEASE:SwissProt: P01229 # Defects in LHB are a cause of hypogonadism [MIM:152780]. Hypogonadism is characterized by infertility and pseudohermaphroditism.
      SIMILARITY: SwissProt: P01229 ## Belongs to the glycoprotein hormones subunit beta family.
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Usage Statement
      • Minimum order quantity required to qualify. Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsMaintain for 1 year at -20°C from date of shipment. Aliquot to avoid repeated freezing and thawing. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
      Packaging Information
      Material SizeBulk packaging. Please inquire.
      Transport Information
      Supplemental Information
      Specifications