203643 BMP-6, Human, Recombinant, E. coli

203643
  
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      Overview

      Replacement Information

      Key Spec Table

      Purity
      ≥95% by SDS-PAGE
      Description
      Overview

      This product has been discontinued.





      Recombinant, human bone morphogenetic protein-6 (BMP-6) expressed in E. coli and purified by proprietary chromatographic methods. BMP-6 is an osteogenic protein belonging to the transforming growth factor-β (TGF-β) superfamily. BMP-6 has been shown to strongly induce phosphorylation and nuclear accumulation of Smad5 and serve as a positive regulator of keratinocyte differentiation.
      Catalogue Number203643
      Brand Family Calbiochem®
      SynonymsBone morphogenetic protein 6 precursor
      References
      ReferencesDai, J., et al. 2005. Cancer Res. 65, 8274.
      Huang, K.K., et al. 2005. J. Periodontal Res. 40, 10.
      Zhang, M., et al. 2005. Chin. Med. J. (Engl.) 118, 1629.
      Akiyoshi, T., et al. 2004. Vet. Pathol. 41, 154.
      Laurent, J.J., et al. 2004. J. Neurosurg. Spine 1, 90.
      Semevolos, S.A., et al. 2004. Am. J. Vet. Res. 65, 110.
      Product Information
      FormLyophilized
      Applications
      Biological Information
      Purity≥95% by SDS-PAGE
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Blue Ice Only
      Toxicity Standard Handling
      Storage -20°C
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
      Packaging Information
      Transport Information
      Supplemental Information
      Specifications

      Documentation

      Certificates of Analysis

      TitleLot Number
      203643

      References

      Reference overview
      Dai, J., et al. 2005. Cancer Res. 65, 8274.
      Huang, K.K., et al. 2005. J. Periodontal Res. 40, 10.
      Zhang, M., et al. 2005. Chin. Med. J. (Engl.) 118, 1629.
      Akiyoshi, T., et al. 2004. Vet. Pathol. 41, 154.
      Laurent, J.J., et al. 2004. J. Neurosurg. Spine 1, 90.
      Semevolos, S.A., et al. 2004. Am. J. Vet. Res. 65, 110.
      Data Sheet

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision10-October-2008 JSW
      SynonymsBone morphogenetic protein 6 precursor
      DescriptionRecombinant, human bone morphogenetic protein-6 (BMP-6) expressed in E. coli and purified by proprietary chromatographic methods. BMP-6 is an osteogenic protein belonging to the transforming growth factor-β (TGF-β) superfamily. BMP-6 has been shown to strongly induce phosphorylation and nuclear accumulation of Smad5 and serve as a positive regulator of keratinocyte differentiation.
      FormLyophilized
      Purity≥95% by SDS-PAGE
      SolubilityReconstitute to ≥100 µg/ml in 20 mM acetic acid. Further dilute with aqueous buffers just prior to use.
      Storage -20°C
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
      Toxicity Standard Handling
      ReferencesDai, J., et al. 2005. Cancer Res. 65, 8274.
      Huang, K.K., et al. 2005. J. Periodontal Res. 40, 10.
      Zhang, M., et al. 2005. Chin. Med. J. (Engl.) 118, 1629.
      Akiyoshi, T., et al. 2004. Vet. Pathol. 41, 154.
      Laurent, J.J., et al. 2004. J. Neurosurg. Spine 1, 90.
      Semevolos, S.A., et al. 2004. Am. J. Vet. Res. 65, 110.