200484 Bestatin - CAS 58970-76-6 - Calbiochem

200484
Price could not be retrieved
Minimum Quantity needs to be mulitiple of
Upon Order Completion More Information
You Saved ()
 
Request Pricing
Limited AvailabilityLimited Availability
In Stock 
Discontinued
Limited Quantities Available
Availability to be confirmed
    Remaining : Will advise
      Remaining : Will advise
      Will advise
      Contact Customer Service
      Contact Customer Service
      View Pricing & Availability
      Click To Print This Page

      Overview

      Replacement Information

      Key Spec Table

      Empirical FormulaCAS #
      C₁₆H₂₄N₂O₄58970-76-6

      Pricing & Availability

      Catalogue NumberAvailability Packaging Qty/Pack Price Quantity
      200484-10MG
      Retrieving availability...
      Limited AvailabilityLimited Availability
      In Stock 
      Discontinued
      Limited Quantities Available
      Availability to be confirmed
        Remaining : Will advise
          Remaining : Will advise
          Will advise
          Contact Customer Service
          Contact Customer Service

          Plastic ampoule 10 mg
          Retrieving price...
          Price could not be retrieved
          Minimum Quantity needs to be mulitiple of
          Upon Order Completion More Information
          You Saved ()
           
          Request Pricing
          Description
          OverviewBinds to cell surfaces and inhibits surface aminopeptidases, notably aminopeptidase B and leucine aminopeptidase. Also acts as a potent aminopeptidase N inhibitor. Activates macrophages and T lymphocytes. Has antitumor properties. Also available as a 50 mM solution in water (Cat. No. 200488).
          Catalogue Number200484
          Brand Family Calbiochem®
          Synonyms[(2S,3R)-3-Amino-2-hydroxy-4-phenylbutanoyl]-Leu
          References
          ReferencesInoue, T., et al. 1994. J. Clin. Endocrinol. Metab. 79, 171.
          Taylor, A., et al. 1993. Biochemistry 32, 784.
          Ishida, J.I., et al. 1984. J. Chromatogr. 305, 381.
          Umezawa, H. 1982. Annu. Rev. Microbiol. 36, 75.
          Product Information
          CAS number58970-76-6
          ATP CompetitiveN
          FormWhite crystalline solid
          Hill FormulaC₁₆H₂₄N₂O₄
          Chemical formulaC₁₆H₂₄N₂O₄
          ReversibleN
          Applications
          ApplicationBestatin, CAS 58970-76-6, is a potent inhibitor of surface aminopeptidases, notably aminopeptidase B, N, and leucine aminopeptidase. Activates macrophages and T lymphocytes.
          Biological Information
          Primary Targetamino peptidase b
          Purity>99% by HPLC
          Physicochemical Information
          Cell permeableN
          Dimensions
          Materials Information
          Toxicological Information
          Safety Information according to GHS
          RTECSOH2915000
          Safety Information
          Product Usage Statements
          Storage and Shipping Information
          Ship Code Ambient Temperature Only
          Toxicity Standard Handling
          Storage +2°C to +8°C
          Do not freeze Ok to freeze
          Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). DMSO and methanol stock solutions are stable for up to 1 month at -20°C.
          Packaging Information
          Transport Information
          Supplemental Information
          Specifications

          Documentation

          SDS

          Title

          Safety Data Sheet (SDS) 

          Certificates of Analysis

          TitleLot Number
          200484

          References

          Reference overview
          Inoue, T., et al. 1994. J. Clin. Endocrinol. Metab. 79, 171.
          Taylor, A., et al. 1993. Biochemistry 32, 784.
          Ishida, J.I., et al. 1984. J. Chromatogr. 305, 381.
          Umezawa, H. 1982. Annu. Rev. Microbiol. 36, 75.

          Citations

          Title
        • Anthony R. White, et al. (2006) Degradation of the alzheimer disease amyloid -peptide by metal-dependent up-regulation of metalloprotease activity. journal of Biological Chemistry 281, 17670-17680.
        • Data Sheet

          Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

          Revision13-May-2013 JSW
          Synonyms[(2S,3R)-3-Amino-2-hydroxy-4-phenylbutanoyl]-Leu
          DescriptionBinds to cell surfaces and inhibits surface aminopeptidases, notably aminopeptidase B and leucine aminopeptidase. Also acts as a potent aminopeptidase N inhibitor. Activates macrophages and T lymphocytes. Has anti-tumor properties. Effective at a concentration of 1-10 µM.
          FormWhite crystalline solid
          CAS number58970-76-6
          RTECSOH2915000
          Chemical formulaC₁₆H₂₄N₂O₄
          Purity>99% by HPLC
          SolubilityDMSO (2 mg/ml) or Methanol (5 mg/ml). Unstable in aqueous solution; dilute just prior to use.
          Storage +2°C to +8°C
          Do Not Freeze Ok to freeze
          Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). DMSO and methanol stock solutions are stable for up to 1 month at -20°C.
          Toxicity Standard Handling
          Merck USA index14, 9842
          ReferencesInoue, T., et al. 1994. J. Clin. Endocrinol. Metab. 79, 171.
          Taylor, A., et al. 1993. Biochemistry 32, 784.
          Ishida, J.I., et al. 1984. J. Chromatogr. 305, 381.
          Umezawa, H. 1982. Annu. Rev. Microbiol. 36, 75.
          Citation
        • Anthony R. White, et al. (2006) Degradation of the alzheimer disease amyloid -peptide by metal-dependent up-regulation of metalloprotease activity. journal of Biological Chemistry 281, 17670-17680.