217588 CD40-Fc Fusion Protein, Human, Recombinant, CHO Cells

217588
  
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      Overview

      Replacement Information
      Description
      Overview

      This product has been discontinued.





      Recombinant, human CD40 (193 amino acids extracellular domain) fused to murine IgG2a Fc (233 amino acids) and expressed in NSO cells. Member of the TNF receptor family. Present on all B cells except plasma cells and on some epithelial cells, carcinomas, and lymphoid dendritic cells. Interaction with its ligand, CD154 (CD40 ligand) is important for isotype switching. Plays an important role in B cell activation.
      Catalogue Number217588
      Brand Family Calbiochem®
      References
      ReferencesHermann, P., et al. 1993. Eur. J. Immunol. 23, 961.
      Armitage, R.J., et al. 1992. Eur. J. Immunol. 22, 2071.
      Product Information
      FormLiquid
      FormulationIn 150 mM NaCl, 100 mM KCl, 50 mM sodium phosphate, 0.5 mg/ml gentamicin sulfate buffer, pH 7.5.
      Applications
      Biological Information
      Purity≥95% by SDS-PAGE
      Concentration Label Please refer to vial label for lot-specific concentration
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Blue Ice Only
      Toxicity Standard Handling
      Storage +2°C to +8°C
      Do not freeze Ok to freeze
      Special InstructionsFollowing initial use, aliquot and freeze (-20°C) for long-term storage.
      Packaging Information
      Transport Information
      Supplemental Information
      Specifications

      Documentation

      SDS

      Title

      Safety Data Sheet (SDS) 

      Certificates of Analysis

      TitleLot Number
      217588

      References

      Reference overview
      Hermann, P., et al. 1993. Eur. J. Immunol. 23, 961.
      Armitage, R.J., et al. 1992. Eur. J. Immunol. 22, 2071.
      Data Sheet

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision03-June-2008 RFH
      DescriptionRecombinant, human CD40 (193 amino acids extracellular domain) fused to murine IgG2a Fc (233 amino acids) and expressed in NSO cells. Member of the TNF receptor family. Present on all B cells except plasma cells and on some epithelial cells, carcinomas, and lymphoid dendritic cells. Interaction with its ligand, CD154 (CD40 ligand) is important for isotype switching. Plays an important role in B cell activation.
      FormLiquid
      FormulationIn 150 mM NaCl, 100 mM KCl, 50 mM sodium phosphate, 0.5 mg/ml gentamicin sulfate buffer, pH 7.5.
      Concentration Label Please refer to vial label for lot-specific concentration
      Purity≥95% by SDS-PAGE
      Storage +2°C to +8°C
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing initial use, aliquot and freeze (-20°C) for long-term storage.
      Toxicity Standard Handling
      ReferencesHermann, P., et al. 1993. Eur. J. Immunol. 23, 961.
      Armitage, R.J., et al. 1992. Eur. J. Immunol. 22, 2071.