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420411 | Kanamycin Sulfate, Streptomyces kanamyceticus, Cell Culture-Tested - CAS 25389-94-0 - Calbiochem

420411
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      Replacement Information

      Tabela com principais espec.

      Empirical FormulaCAS #
      C₁₈H₃₆N₄O₁₁ · H₂SO₄ 25389-94-0

      Preço e Disponibilidade

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      US1420411-25GM
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          Description
          OverviewAn aminoglycoside antibiotic effective against Gram-positive and Gram-negative organisms. Inhibitor of protein biosynthesis that acts on the 30S ribosome, causing misreading of the genetic code. May cause renal damage and ototoxicity.
          Contains >98% kanamycin A. Potency: ≥750 µg/mg
          Recommended working concentration: 100 µg/ml.
          Catalogue Number420411
          Brand Family Calbiochem®
          References
          ReferencesLech, K., and Brent, R. 1995. in Current Protocols in Mol. Biol. Vol. 1 (Ausubel, F.M., et al., Eds.) John Wiley & Sons, New York.
          Cardon, G.H., et al. 1993. Plant J. 3, 773.
          Maniatis, T., et al. 1989. In Molecular Cloning, A Laboratory Manual, Second Edition. Cold Spring Harbor, New York. p.1.6, A.6.
          Korzybyski, T., et al. 1978. In Antibiotics, Origin, Nature, and Properties 1, 690.
          Stiffler, P.W., et al. 1974. Antimicrob. Agents Chemother. 6, 516.
          Umezawa, S., et al. 1968. J. Antibiot. 21, 367.
          Product Information
          CAS number25389-94-0
          FormWhite to off-white solid
          Hill FormulaC₁₈H₃₆N₄O₁₁ · H₂SO₄
          Chemical formulaC₁₈H₃₆N₄O₁₁ · H₂SO₄
          Applications
          Biological Information
          Primary Targetprotein biosynthesis that acts on the 30S ribosome
          Physicochemical Information
          Dimensions
          Materials Information
          Toxicological Information
          Safety Information according to GHS
          RTECSNZ3225030
          Safety Information
          R PhraseR: 36/37/38-42/43-60-61

          Irritating to eyes, respiratory system and skin.
          May cause sensitization by inhalation and skin contact.
          May impair fertility.
          May cause harm to the unborn child.
          S PhraseS: 26-36/37/39-45

          In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
          Wear suitable protective clothing, gloves and eye/face protection.
          In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible).
          Product Usage Statements
          Storage and Shipping Information
          Ship Code Ambient Temperature Only
          Toxicity Carcinogenic / Teratogenic
          Storage +15°C to +30°C
          Do not freeze Ok to freeze
          Special InstructionsFollowing reconstitution, sterilize by filtration through a 0.22 µm pore-size filter, aliquot and freeze (-20°C). Stock solutions are stable for up to 1 year at -20°C.
          Packaging Information
          Transport Information
          Supplemental Information
          Specifications

          Documentation

          MSDS

          Título

          Ficha de Segurança de Produtos (MSDS) 

          Certificados de análise

          TítuloNúmero do lote
          420411

          Referências

          Visão geral de referência
          Lech, K., and Brent, R. 1995. in Current Protocols in Mol. Biol. Vol. 1 (Ausubel, F.M., et al., Eds.) John Wiley & Sons, New York.
          Cardon, G.H., et al. 1993. Plant J. 3, 773.
          Maniatis, T., et al. 1989. In Molecular Cloning, A Laboratory Manual, Second Edition. Cold Spring Harbor, New York. p.1.6, A.6.
          Korzybyski, T., et al. 1978. In Antibiotics, Origin, Nature, and Properties 1, 690.
          Stiffler, P.W., et al. 1974. Antimicrob. Agents Chemother. 6, 516.
          Umezawa, S., et al. 1968. J. Antibiot. 21, 367.

          Brochura

          Título
          Antibiotics Profiler
          Ficha de dados

          Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

          Revision24-September-2010 JSW
          DescriptionAn aminoglycoside antibiotic effective against Gram-positive and Gram-negative organisms. Inhibitor of protein biosynthesis that acts on the 70S ribosome, causing misreading of the genetic code. May cause renal damage and ototoxicity. Useful for the selection of kanamycin resistant plasmids in E. coli. Tested and found to be negative for cytotoxicity against HeLa cells. Contains more than 98% kanamycin A.
          FormWhite to off-white solid
          CAS number25389-94-0
          RTECSNZ3225030
          Chemical formulaC₁₈H₃₆N₄O₁₁ · H₂SO₄
          SolubilityH₂O (10 mg/ml)
          Storage +15°C to +30°C
          Do Not Freeze Ok to freeze
          Special InstructionsFollowing reconstitution, sterilize by filtration through a 0.22 µm pore-size filter, aliquot and freeze (-20°C). Stock solutions are stable for up to 1 year at -20°C.
          Toxicity Carcinogenic / Teratogenic
          Merck USA index14, 5281
          ReferencesLech, K., and Brent, R. 1995. in Current Protocols in Mol. Biol. Vol. 1 (Ausubel, F.M., et al., Eds.) John Wiley & Sons, New York.
          Cardon, G.H., et al. 1993. Plant J. 3, 773.
          Maniatis, T., et al. 1989. In Molecular Cloning, A Laboratory Manual, Second Edition. Cold Spring Harbor, New York. p.1.6, A.6.
          Korzybyski, T., et al. 1978. In Antibiotics, Origin, Nature, and Properties 1, 690.
          Stiffler, P.W., et al. 1974. Antimicrob. Agents Chemother. 6, 516.
          Umezawa, S., et al. 1968. J. Antibiot. 21, 367.