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HMHEMAG-34K | MILLIPLEX MAP Human Metabolic Hormone Magnetic Bead Panel - Metabolism Multiplex Assay

HMHEMAG-34K
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Replacement Information
Replacement InformationHuman Metabolic Hormone Magnetic Bead Panel (HMHMAG-34K).

Tabela com principais espec.

Analytes AvailableSpecies ReactivityKey ApplicationsMultiplexing Ordering RequirementsDetection Methods
Amylin (Total), Amylin (Active), C-Peptide, Ghrelin, GIP, GLP-1 (Active), GLP-1 (Total), Glucagon, IL-6, Insulin, Leptin, MCP-1, PP, PYY, TNF-α H Mplex Please note: Active Amylin and Total Amylin cannot be plexed together. Active and total GLP-1 cannot be plexed together. Luminex xMAP
Description
Catalogue NumberHMHEMAG-34K
ReplacesHMHMAG-34K
Trade Name
  • MILLIPLEX
DescriptionMILLIPLEX MAP Human Metabolic Hormone Magnetic Bead Panel - Metabolism Multiplex Assay
Background InformationMetabolic syndrome is a cluster of conditions that occur together, including increased blood pressure, elevated insulin levels, excess body fat around the waist, and abnormal cholesterol levels.

Key features of metabolic syndrome include insulin resistance, glucose intolerance, hypertension, dyslipidemia, and central obesity—all of which are risk factors for atherosclerosis, coronary heart disease, type 2 diabetes, kidney disease, and even premature death.

Adults with metabolic syndrome present a low-grade inflammation, whose link with obesity may be a production of pro- and anti-inflammatory factors. Consequently, research done in this area covers multi-faceted fields of cytokines, acute phase proteins, diabetes and obesity related hormones, as well as other cardiovascular disease biomarkers.
References
Product Information
Detection methodLuminex xMAP
ConfigurationDesign your multiplex kit by choosing available analytes within this panel.
Precision, %
  • Intra-assay: <10%
  • Inter-assay: <15%
Multiplex Ordering RequirementsPlease note: Active Amylin and Total Amylin cannot be plexed together. Active and total GLP-1 cannot be plexed together.
Panel TypeMAGNETIC Metabolism
Applications
ApplicationThe analytes available for this multiplex kit are: Amylin (Total), Amylin (Active), C-Peptide, Ghrelin (Active), GIP (Total), GLP-1 (Active), Glucagon, IL-6, Insulin, Leptin, MCP-1, PP, PYY, TNF-α.
Key Applications
  • Multiplexing
Application Notes• There are 15 biomarkers to choose from in this kit. However, since Amylin active and total (and GLP-1 active and total) cannot be run simultaneously, this is a 13-plex kit.
• Several of the analytes require addition or DPPIV, Aprotinin and/or serine protease inhibitor. See sample collection and storage section in the protocol for details.
• The protocol recommends samples be run neat, using an overnight incubation for optimal sensitivity.
Biological Information
Species Reactivity
  • Human
Analytes Available
  • Amylin (Total)
  • Amylin (Active)
  • C-Peptide
  • Ghrelin
  • GIP
  • GLP-1 (Active)
  • GLP-1 (Total)
  • Glucagon
  • IL-6
  • Insulin
  • Leptin
  • MCP-1
  • PP
  • PYY
  • TNF-α
Accuracy
  • 97% - 107%
Physicochemical Information
Sensitivity
  • 0.5 - 160 pg/mL (+2SD)
  • Please see kit protocol for individual assay sensitivities.
Standard Curve Range
  • Amylin (active): 13.7-10,000 pg/mL
  • Amylin (total): 13.7-10,000 pg/mL
  • C-Peptide: 27.4-20,000 pg/mL
  • Ghrelin: 13.7-10,000 pg/mL
  • GIP: 1.4-1,000 pg/mL
  • GLP-1 (active): 2.7-2,000 pg/mL
  • GLP-1 (total): 2.7-2,000 pg/mL
  • Glucagon: 13.7-10,000 pg/mL
  • IL-6: 13.7-10,000 pg/mL
  • Insulin: 137-100,000 pg/mL
  • Leptin: 137-100,000 pg/mL
  • MCP-1: 13.7-10,000 pg/mL
  • PP: 2.7-2,000 pg/mL
  • PYY: 13.7-10,000 pg/mL
  • TNFα: 0.69-500 pg/mL
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Packaging Information
Material Size96-well plate
Transport Information
Supplemental Information
Specifications

Documentation

Protocols

Title
Protocol: Human Metabolic Hormone Magnetic Bead Panel

MSDS

Título

Ficha de Segurança de Produtos (MSDS) 

Brochura

Título
A closer look at immunoassay platforms. Beyond fit for purpse. Bring your biomarkers to life with Merck Millipore Immunoassay Platform Solutions.
Immunoassay and Multiplex Kits: Analyte Quarterly Vol. 2, 2016
Protein Detection Platform and Services Brochure
The Power of Biomarker Analysis

Informações técnicas

Título
96 well Template 2 Up
96 well Template Single
HMHEMAG-34K xPonent Procotol Template Version Magpix
HMHEMAG-34K xPonent Standard Template Version Magpix
MILLIPLEX® MAP metabolic hormones in human serum and plasma
QUALITY CONTROL RANGES Milliplex Human Metabolic Hormone Magnetic Bead Panel

Ficha de dados

Título
Full Service Custom-built Assays

Pôster

Título
Multiplex Assays of Fifteen Human Complement Factors