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MAB8703 | Anti-Dengue Virus Type III Antibody, clone 5D4-11

MAB8703
100 µg  
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      Descripción

      Replacement Information

      Ofertas especiales

      Tabla espec. clave

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      H IF M Purified Monoclonal Antibody
      Description
      Catalogue NumberMAB8703
      Brand Family Chemicon®
      Trade Name
      • Chemicon
      DescriptionAnti-Dengue Virus Type III Antibody, clone 5D4-11
      Background InformationDengue fever is an acute, mosquito-transmitted viral disease characterized by fever, headache, arthralgia (severe retro-orbital pain), myalgia, rash, nausea, and vomiting. Infections are caused by any of the four closely related, but antigenically distinct virus serotypes (DEN-1, DEN-2, DEN-3, and DEN-4). Infection with one of these serotypes does not provide cross-protective immunity, so persons living in a dengue-endemic area can have four dengue infections during their lifetimes. Dengue is primarily an urban disease of the tropics, and the viruses that cause it are maintained in a cycle that involves humans and Aedes aegypti, a domestic, day-biting mosquito that prefers to feed on humans. Although most dengue infections result in relatively mild illness, some can produce Dengue Hemorrhagic Fever (DHF) or dengue shock syndrome, with children being particularly at risk. Although epidemic outbreaks have been reported since 1779, the incidence has been increasing, with global, multiple serotype pandemics intensifying within the last 15 years. There is no specific antiviral therapy for dengue, but for both classical dengue and dengue hemorrhagic fever, symptomatic and supportive measures are effective. Important risk factors for DHF include the strain and serotype of the virus involved, as well as the age, immune status, and genetic predisposition of the patient.
      References
      Product Information
      FormatPurified
      PresentationPurified. 0.02M Phosphate Buffer, pH 7.6, 0.25M NaCl and 0.1% sodium azide.
      Applications
      ApplicationAnti-Dengue Virus Type III Antibody, clone 5D4-11 is an antibody against Dengue Virus Type III for use in IF.
      Key Applications
      • Immunofluorescence
      Application NotesImmunofluorescent assay.

      Final working dilutions must be determined by end user.
      Biological Information
      ImmunogenDengue virus antigens (H87).
      Clone5D4-11
      ConcentrationPlease refer to the Certificate of Analysis for the lot-specific concentration.
      HostMouse
      SpecificityReacts with the Dengue type 3 virus.
      IsotypeIgG1
      Species Reactivity
      • Human
      Antibody TypeMonoclonal Antibody
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsMaintain at 2-8°C in undiluted aliquots for up to 12 months. Avoid repeated freeze/thaw cycles.
      Packaging Information
      Material Size100 µg
      Transport Information
      Supplemental Information
      Specifications

      Documentation

      Ficha datos de seguridad (MSDS)

      Título

      Ficha técnica de seguridad del material (MSDS) 

      Certificados de análisis

      CargoNúmero de lote
      MOUSE ANTI-DENGUE TYPE 3 VIRUS MONOCLONAL ANTIBODY - 2118026 2118026
      MOUSE ANTI-DENGUE TYPE 3 VIRUS MONOCLONAL ANTIBODY - 2123649 2123649
      MOUSE ANTI-DENGUE TYPE 3 VIRUS MONOCLONAL ANTIBODY - 2127793 2127793
      MOUSE ANTI-DENGUE TYPE 3 VIRUS MONOCLONAL ANTIBODY - 2322539 2322539
      MOUSE ANTI-DENGUE TYPE 3 VIRUS MONOCLONAL ANTIBODY - 2382628 2382628
      MOUSE ANTI-DENGUE TYPE 3 VIRUS MONOCLONAL ANTIBODY - 2420431 2420431
      MOUSE ANTI-DENGUE TYPE 3 VIRUS MONOCLONAL ANTIBODY - 2455594 2455594
      MOUSE ANTI-DENGUE TYPE 3 VIRUS MONOCLONAL ANTIBODY - 2153025 2153025
      MOUSE ANTI-DENGUE TYPE 3 VIRUS - 2529979 2529979
      MOUSE ANTI-DENGUE TYPE 3 VIRUS -2577020 2577020
      MOUSE ANTI-DENGUE TYPE 3 VIRUS -2721722 2721722
      MOUSE ANTI-DENGUE TYPE 3 VIRUS -2776275 2776275
      MOUSE ANTI-DENGUE TYPE 3 VIRUS -2790702 2790702
      MOUSE ANTI-DENGUE TYPE 3 VIRUS MONOCLONAL ANTIBODY - 2299967 2299967

      Referencias bibliográficas

      Visión general referenciasPub Med ID
      Evaluation by flow cytometry of antibody-dependent enhancement (ADE) of dengue infection by sera from Thai children immunized with a live-attenuated tetravalent dengue vaccine.
      Bruno Guy, Pornthep Chanthavanich, Sophie Gimenez, Chukiat Sirivichayakul, Arunee Sabchareon, Sarah Begue, Sutee Yoksan, Christine Luxemburger, Jean Lang
      Vaccine 22 3563-74 2004

      Mostrar resumen
      15315835 15315835
      Identification of distinct antigenic determinants on dengue-2 virus using monoclonal antibodies.
      Gentry, M K, et al.
      Am. J. Trop. Med. Hyg., 31: 548-55 (1982) 1982

      Mostrar resumen
      6177259 6177259
      Dengue virus-specific and flavivirus group determinants identified with monoclonal antibodies by indirect immunofluorescence
      Henchal, E A, et al
      Am J Trop Med Hyg, 31:830-6 (1982) 1982

      6285749 6285749

      Ficha técnica

      Cargo
      Anti-Dengue Virus Type III, clone 5D4-11 - Data Sheet