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MAB1482 | Anti-Trypsin Antibody, human pancreas

MAB1482
100 µL  
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      Descripción

      Replacement Information

      Ofertas especiales

      Tabla espec. clave

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      H ELISA M Ascites Monoclonal Antibody
      Description
      Catalogue NumberMAB1482
      Brand Family Chemicon®
      Trade Name
      • Chemicon
      DescriptionAnti-Trypsin Antibody, human pancreas
      References
      Product Information
      FormatAscites
      Applications
      ApplicationAnti-Trypsin Antibody, human pancreas detects level of Trypsin & has been published & validated for use in ELISA.
      Key Applications
      • ELISA
      Application NotesImmunohistochestry/IH(P): {Solakidi, et al. 2003} 1:100-1:500; formalin fixed, paraffin embedded human tissues; 5μm serial sections; blocking solution 0.5% serum in PBS; overnight incubations; enzymatic detection.

      ELISA at 1:25,600.
      Biological Information
      ImmunogenPurified human pancreatic trypsin.
      Epitopehuman pancreas
      HostMouse
      SpecificityRecognizes trypsin -1
      IsotypeIgG2b
      Species Reactivity
      • Human
      Antibody TypeMonoclonal Antibody
      Entrez Gene Number
      Entrez Gene SummaryThis gene encodes a trypsinogen, which is a member of the trypsin family of serine proteases. This enzyme is secreted by the pancreas and cleaved to its active form in the small intestine. It is active on peptide linkages involving the carboxyl group of lysine or arginine. Mutations in this gene are associated with hereditary pancreatitis. This gene and several other trypsinogen genes are localized to the T cell receptor beta locus on chromosome 7.
      Gene Symbol
      • PRSS1
      • MGC120175
      • PCTT
      • HPC
      • TRY4
      • TRYP1
      • MGC149362
      • TRP1
      • TRY1
      • EC 3.4.21.4
      UniProt Number
      UniProt SummaryCOFACTOR: Binds 1 calcium ion per subunit.
      SIZE: 247 amino acids; 26558 Da
      SUBCELLULAR LOCATION: Secreted, extracellular space.
      DISEASE: SwissProt: P07477 # Defects in PRSS1 are a cause of hereditary pancreatitis (HPC) [MIM:167800]; also known as chronic pancreatitis (CP). HPC is an autosomal dominant disease characterized by the presence of calculi in pancreatic ducts. It causes severe abdominal pain attacks.
      SIMILARITY: SwissProt: P07477 ## Belongs to the peptidase S1 family. & Contains 1 peptidase S1 domain.
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsMaintain at -20°C in convenient aliquots for up to 12 months. Avoid repeated freeze/thaw cycles.
      Packaging Information
      Material Size100 µL
      Transport Information
      Supplemental Information
      Specifications

      Documentation

      Ficha datos de seguridad (MSDS)

      Título

      Ficha técnica de seguridad del material (MSDS) 

      Certificados de análisis

      CargoNúmero de lote
      MOUSE ANTI-TRYPSIN MONOCLONAL ANTIBODY - 2147010 2147010
      MOUSE ANTI-TRYPSIN MONOCLONAL ANTIBODY - 2453172 2453172
      MOUSE ANTI-TRYPSIN - 2716533 2716533
      MOUSE ANTI-TRYPSIN -2521481 2521481
      MOUSE ANTI-TRYPSIN -2681280 2681280
      MOUSE ANTI-TRYPSIN -2736439 2736439
      MOUSE ANTI-TRYPSIN -2822809 2822809
      MOUSE ANTI-TRYPSIN MONOCLONAL ANTIBODY - 1992264 1992264
      MOUSE ANTI-TRYPSIN MONOCLONAL ANTIBODY - 2034691 2034691

      Referencias bibliográficas

      Visión general referenciasPub Med ID
      Tumour-associated trypsin inhibitor TATI is a prognostic marker in colorectal cancer.
      Selja Koskensalo,Jaana Hagström,Johanna Louhimo,Ulf-Håkan Stenman,Caj Haglund
      Oncology 82 2012

      Mostrar resumen
      22508321 22508321
      Paneth cell hyperplasia and metaplasia in necrotizing enterocolitis.
      Patrycja J Puiman,Nanda Burger-Van Paassen,Maaike W Schaart,Adrianus C J M De Bruijn,Ronald R De Krijger,Dick Tibboel,Johannes B Van Goudoever,Ingrid B Renes
      Pediatric research 69 2011

      Mostrar resumen
      21372757 21372757
      Proinflammatory and proliferative responses of human proximal tubule cells to PAR-2 activation.
      Vesey, DA; Kruger, WA; Poronnik, P; Gobé, GC; Johnson, DW
      American journal of physiology. Renal physiology 293 F1441-9 2007

      Mostrar resumen
      17699557 17699557
      Experience with an automated microwave-assisted rapid tissue processing method: validation of histologic quality and impact on the timeliness of diagnostic surgical pathology.
      Morales, AR; Nassiri, M; Kanhoush, R; Vincek, V; Nadji, M
      American journal of clinical pathology 121 528-36 2004

      Mostrar resumen
      15080304 15080304

      Ficha técnica

      Cargo
      MOUSE ANTI-TRYPSIN MONOCLONAL ANTIBODY