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205546 | Caffeic Acid - CAS 331-39-5 - Calbiochem

205546
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      Descripción

      Replacement Information

      Tabla espec. clave

      Empirical FormulaCAS #
      C₉H₈O₄ 331-39-5

      Precios y disponibilidad

      Número de referenciaDisponiblidad Embalaje Cant./Env. Precio Cantidad
      US1205546-500MG
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      Disponibilidad a confirmarDisponibilidad a confirmar
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      Debe confirmarse disponibilidad
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          Frasco de vidrio 500 mg
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          Description
          OverviewA natural dietary compound reported to have anti-carcinogenic and anti-inflammatory properties. A cell-permeable, selective, non-competitive inhibitor of 5-lipoxygenase (ID50 = 3.7 µM). Inhibits Cu2+-induced LDL oxidation in the initiation phase but acts as a prooxidant in the propagation phase. An irreversible inhibitor of glutathione S-transferases and a non-competitive inhibitor of xanthine oxidase.
          Catalogue Number205546
          Brand Family Calbiochem®
          Synonyms3,4-Dihydroxycinnamic Acid
          References
          ReferencesYamanaka, N., et al. 1997. FEBS Lett. 405, 186.
          Chan, W.S., et al. 1995. Anticancer Res. 15, 703.
          Ploemen, J.H., et al. 1993. Food Chem. Toxicol. 31, 475.
          Koshihara, Y., et al. 1984. Biochim. Biophys. Acta 792, 92.
          Product Information
          CAS number331-39-5
          ATP CompetitiveN
          FormTan crystalline solid
          Hill FormulaC₉H₈O₄
          Chemical formulaC₉H₈O₄
          ReversibleN
          Structure formula Image
          Applications
          Biological Information
          Primary Target5-lipoxygenase
          Primary Target IC<sub>50</sub>3.7 µM against 5-lipoxygenase
          Purity≥95% by HPLC
          Physicochemical Information
          Cell permeableY
          Dimensions
          Materials Information
          Toxicological Information
          Safety Information according to GHS
          RTECSGD8950000
          Safety Information
          R PhraseR: 40

          Limited evidence of a carcinogenic effect.
          S PhraseS: 36/37

          Wear suitable protective clothing and gloves.
          Product Usage Statements
          Storage and Shipping Information
          Ship Code Ambient Temperature Only
          Toxicity Carcinogenic / Teratogenic
          Storage +2°C to +8°C
          Do not freeze Ok to freeze
          Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
          Packaging Information
          Packaged under inert gas Packaged under inert gas
          Transport Information
          Supplemental Information
          Specifications

          Documentation

          Ficha datos de seguridad (MSDS)

          Título

          Ficha técnica de seguridad del material (MSDS) 

          Certificados de análisis

          CargoNúmero de lote
          205546

          Referencias bibliográficas

          Visión general referencias
          Yamanaka, N., et al. 1997. FEBS Lett. 405, 186.
          Chan, W.S., et al. 1995. Anticancer Res. 15, 703.
          Ploemen, J.H., et al. 1993. Food Chem. Toxicol. 31, 475.
          Koshihara, Y., et al. 1984. Biochim. Biophys. Acta 792, 92.
          Ficha técnica

          Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

          Revision28-April-2008 RFH
          Synonyms3,4-Dihydroxycinnamic Acid
          DescriptionA cell-permeable natural dietary compound reported to have anti-carcinogenic and anti-inflammatory properties. A selective, non-competitive inhibitor of 5-lipoxygenase (ID50 = 3.7 µM). Inhibits Cu2+-induced LDL oxidation in the initiation phase but acts as a prooxidant in the propagation phase. An effective irreversible inhibitor of glutathione S-transferases and a non-competitive inhibitor of xanthine oxidase.
          FormTan crystalline solid
          Intert gas (Yes/No) Packaged under inert gas
          CAS number331-39-5
          RTECSGD8950000
          Chemical formulaC₉H₈O₄
          Structure formula
          Purity≥95% by HPLC
          SolubilityDMSO (200 mg/ml) or Ethanol (50 mg/ml)
          Storage +2°C to +8°C
          Do Not Freeze Ok to freeze
          Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
          Toxicity Carcinogenic / Teratogenic
          Merck USA index14, 1635
          ReferencesYamanaka, N., et al. 1997. FEBS Lett. 405, 186.
          Chan, W.S., et al. 1995. Anticancer Res. 15, 703.
          Ploemen, J.H., et al. 1993. Food Chem. Toxicol. 31, 475.
          Koshihara, Y., et al. 1984. Biochim. Biophys. Acta 792, 92.