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230752 | Chromomycin A₃ - CAS 7059-24-7 - Calbiochem

230752
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      Descripción

      Replacement Information

      Tabla espec. clave

      Empirical FormulaCAS #
      C₅₇H₈₂O₂₆ 7059-24-7

      Precios y disponibilidad

      Número de referenciaDisponiblidad Embalaje Cant./Env. Precio Cantidad
      US1230752-10MG
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      Disponibilidad a confirmarDisponibilidad a confirmar
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          10 mg
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          Description
          OverviewAntitumor antibiotic that inhibits RNA synthesis. A cell-permeable fluorescent dye that can be used with Bisbenzimide H 33258 (Cat. No. 382061) to distinguish chromosomes by their total DNA content and DNA base composition. Reversibly interacts with DNA in the presence of Mg2+. Binds to G:C pairs of helical DNA but does not intercalate.
          Catalogue Number230752
          Brand Family Calbiochem®
          SynonymsToyomycin
          References
          ReferencesAich, P., et al. 1992. Biochemistry 31, 2988.
          Saccone, S., et al. 1992. Proc. Natl. Acad. Sci. USA 89, 4913.
          Van Dilla, M.A., et al. 1983. Science 220, 620.
          Mizuno, K. 1963. J. Antibiot. 16, 22.
          Product Information
          CAS number7059-24-7
          FormYellow solid
          Hill FormulaC₅₇H₈₂O₂₆
          Chemical formulaC₅₇H₈₂O₂₆
          Structure formula Image
          Applications
          Biological Information
          Purity≥90% by HPLC
          Physicochemical Information
          Emission max.
          Excitation max.
          Dimensions
          Materials Information
          Toxicological Information
          Safety Information according to GHS
          RTECSGB7875000
          Safety Information
          R PhraseR: 26/27/28-61

          Very toxic by inhalation, in contact with skin and if swallowed.
          May cause harm to the unborn child.
          S PhraseS: 26-36/37/39-45

          In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
          Wear suitable protective clothing, gloves and eye/face protection.
          In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible).
          Product Usage Statements
          Storage and Shipping Information
          Ship Code Ambient Temperature Only
          Toxicity Highly Toxic & Carcinogenic / Teratogenic
          Hazardous Materials Attention: Due to the nature of the Hazardous Materials in this shipment, additional shipping charges may be applied to your order. Certain sizes may be exempt from the additional hazardous materials shipping charges. Please contact your local sales office for more information regarding these charges.
          Storage +2°C to +8°C
          Protect from Light Protect from light
          Do not freeze Ok to freeze
          Special InstructionsFollowing recosntitution aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
          Packaging Information
          Transport Information
          Supplemental Information
          Specifications

          Documentation

          Ficha datos de seguridad (MSDS)

          Título

          Ficha técnica de seguridad del material (MSDS) 

          Certificados de análisis

          CargoNúmero de lote
          230752

          Referencias bibliográficas

          Visión general referencias
          Aich, P., et al. 1992. Biochemistry 31, 2988.
          Saccone, S., et al. 1992. Proc. Natl. Acad. Sci. USA 89, 4913.
          Van Dilla, M.A., et al. 1983. Science 220, 620.
          Mizuno, K. 1963. J. Antibiot. 16, 22.

          Folleto

          Cargo
          Dyes and Stains Technical Bulletin
          Ficha técnica

          Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

          Revision29-April-2008 RFH
          SynonymsToyomycin
          DescriptionAntibiotic that inhibits RNA synthesis by way of DNA-dependent RNA polymerase. Fluorescent dye that can be used in conjunction with Bisbenzimide H33258 (Cat. No. 382061) to distinguish chromosomes by their total DNA concentration and their DNA base composition. Binds to G:C pairs of helical DNA (Mg2+ required) but does not intercalate the A:T pairs, which preferentially bind Bisbenzimide H33258.
          FormYellow solid
          CAS number7059-24-7
          RTECSGB7875000
          Chemical formulaC₅₇H₈₂O₂₆
          Structure formula
          Purity≥90% by HPLC
          SolubilityEthanol (10 mg/ml)
          Storage +2°C to +8°C
          Protect from light
          Do Not Freeze Ok to freeze
          Special InstructionsFollowing recosntitution aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
          Toxicity Highly Toxic & Carcinogenic / Teratogenic
          Merck USA index14, 2238
          ReferencesAich, P., et al. 1992. Biochemistry 31, 2988.
          Saccone, S., et al. 1992. Proc. Natl. Acad. Sci. USA 89, 4913.
          Van Dilla, M.A., et al. 1983. Science 220, 620.
          Mizuno, K. 1963. J. Antibiot. 16, 22.