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356780 | Glycyrrhizin, Ammonium Salt - CAS 53956-04-0 - Calbiochem

356780
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      Descripción

      Replacement Information

      Tabla espec. clave

      Empirical FormulaCAS #
      C₄₂H₆₁O₁₆ • NH₄ 53956-04-0

      Precios y disponibilidad

      Número de referenciaDisponiblidad Embalaje Cant./Env. Precio Cantidad
      US1356780-5GM
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          Description
          OverviewA triterpenoid saponin isolated from liquorice roots that displays antiviral and anti-tumor activities. Inhibits replication, adsorption, and penetration of severe acute respiratory syndrome-associated coronavirus (SARS-CV), presumably via its ability to upregulate nitric oxide synthase activity. Reported to block the growth of other viruses, including herpes virus, and helps restore liver functions in patients with hepatitis C. It is allso a known 11β-hydroxysteroid dehydrogenase type 2 (11-HSD2) inhibitor.
          Catalogue Number356780
          Brand Family Calbiochem®
          SynonymsGlycyrrhizic Acid, NH₄+
          References
          ReferencesCinatl, J., et al. 2003. Lancet 361, 2045.
          Tanahashi, T., et al. 2002. J. Steroid Biochem. Mol. Biol. 80, 441.
          Kondo, Y., and Takano, F. 1994. Biol. Pharm. Bull. 17, 759.
          Product Information
          CAS number53956-04-0
          FormLight yellow solid
          Hill FormulaC₄₂H₆₁O₁₆ • NH₄
          Chemical formulaC₄₂H₆₁O₁₆ • NH₄
          Hygroscopic Hygroscopic
          Structure formula Image
          Applications
          Biological Information
          Purity≥95% by HPLC
          Physicochemical Information
          Dimensions
          Materials Information
          Toxicological Information
          Safety Information according to GHS
          RTECSLZ6500000
          Safety Information
          Product Usage Statements
          Storage and Shipping Information
          Ship Code Ambient Temperature Only
          Toxicity Standard Handling
          Storage +2°C to +8°C
          Hygroscopic Hygroscopic
          Do not freeze Ok to freeze
          Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
          Packaging Information
          Packaged under inert gas Packaged under inert gas
          Transport Information
          Supplemental Information
          Specifications

          Documentation

          Ficha datos de seguridad (MSDS)

          Título

          Ficha técnica de seguridad del material (MSDS) 

          Certificados de análisis

          CargoNúmero de lote
          356780

          Referencias bibliográficas

          Visión general referencias
          Cinatl, J., et al. 2003. Lancet 361, 2045.
          Tanahashi, T., et al. 2002. J. Steroid Biochem. Mol. Biol. 80, 441.
          Kondo, Y., and Takano, F. 1994. Biol. Pharm. Bull. 17, 759.
          Ficha técnica

          Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

          Revision07-September-2013 JSW
          SynonymsGlycyrrhizic Acid, NH₄+
          DescriptionA triterpenoid saponin, isolated from liquorice roots, that exhibits anti-viral and anti-tumor activities. Inhibits replication, adsorption, and penetration of severe acute respiratory syndrome-associated coronavirus (SARS-CV), presumably as a result of its ability to upregulate nitric oxide synthase activity. Also reported to hamper the growth of other viruses, including herpes virus. Shown to restore liver function in patients with hepatitis C virus (HCV). Also shown to inhibit 11β-hydroxysteroid dehydrogenase type 2 (11-HSD2).
          FormLight yellow solid
          Intert gas (Yes/No) Packaged under inert gas
          CAS number53956-04-0
          RTECSLZ6500000
          Chemical formulaC₄₂H₆₁O₁₆ • NH₄
          Structure formula
          Purity≥95% by HPLC
          SolubilityAqueous NH₄OH (50 mg/ml)
          Storage +2°C to +8°C
          Hygroscopic
          Do Not Freeze Ok to freeze
          Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
          Toxicity Standard Handling
          Merck USA index14, 4505
          ReferencesCinatl, J., et al. 2003. Lancet 361, 2045.
          Tanahashi, T., et al. 2002. J. Steroid Biochem. Mol. Biol. 80, 441.
          Kondo, Y., and Takano, F. 1994. Biol. Pharm. Bull. 17, 759.