A part of Merck

3779 | Histamine, Free Base - CAS 51-45-6 - Calbiochem

3779
No pudo obtenerse el precio
La cantidad mínima tiene que ser múltiplo de
Al finalizar el pedido Más información
Ahorró ()
 
Solicitar precio
Disponibilidad a confirmarDisponibilidad a confirmar
En existencia 
Suspendido
Cantidades limitadas disponibles
Debe confirmarse disponibilidad
    El resto: se avisará
      El resto: se avisará
      Se avisará
      Póngase en contacto con el Servicio de Atención al Cliente
      Ver precios y disponibilidad
      Click To Print This Page

      Descripción

      Replacement Information

      Tabla espec. clave

      Empirical FormulaCAS #
      C₅H₉N₃ 51-45-6

      Precios y disponibilidad

      Número de referenciaDisponiblidad Embalaje Cant./Env. Precio Cantidad
      US13779-1GM
      Comprobando disponibilidad...
      Disponibilidad a confirmarDisponibilidad a confirmar
      En existencia 
      Suspendido
      Cantidades limitadas disponibles
      Debe confirmarse disponibilidad
        El resto: se avisará
          El resto: se avisará
          Se avisará
          Póngase en contacto con el Servicio de Atención al Cliente

          Frasco de vidrio 1 gm
          Recuperando precio...
          No pudo obtenerse el precio
          La cantidad mínima tiene que ser múltiplo de
          Al finalizar el pedido Más información
          Ahorró ()
           
          Solicitar precio
          Description
          OverviewA potent vasodilator found in normal tissues and blood. Activates nitric oxide synthase. Formed by the decarboxylation of L-histidine. Activation of histamine H1 receptors leads to Ca2+ mobilization, whereas histamine H2 receptor activation stimulates adenylate cyclase activity in neurons. Stimulated time- and concentration-dependent increase in p38 and p42/p44 MAP kinases in DDT(1) MF2 cells.
          Catalogue Number3779
          Brand Family Calbiochem®
          Synonyms2-(4-Imidazolyl)ethylamine
          References
          ReferencesRobinson, A.J., and Dickerson, J.M. 2001. Br. J. Pharmacol. 133, 178.
          Izumi, H., et al. 1995. Am. J. Obstet. Gynecol. 172, 1477.
          Vannier, E., and Dinarello, C.A. 1994. J. Biol. Chem. 269, 9952.
          Yan, Q.Z., et al. 1994. Agents Actions 41, C111.
          Moncada, S., et al. 1991. Pharmacol. Rev. 43, 109.
          Bloom, F.E. 1990. in Pharmacological Basis of Therapeutics p. 224 (Gilman, A.G., et al., Eds.) Pergamon Press, New York.
          Product Information
          CAS number51-45-6
          FormWhite solid
          Hill FormulaC₅H₉N₃
          Chemical formulaC₅H₉N₃
          Hygroscopic Hygroscopic
          Structure formula Image
          Applications
          Biological Information
          Purity≥97% by TLC
          Physicochemical Information
          Dimensions
          Materials Information
          Toxicological Information
          Safety Information according to GHS
          RTECSMS1050000
          Safety Information
          R PhraseR: 22-36/37/38-42/43

          Harmful if swallowed.
          Irritating to eyes, respiratory system and skin.
          May cause sensitization by inhalation and skin contact.
          S PhraseS: 26-36/37-22

          In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
          Wear suitable protective clothing and gloves.
          Do not breathe dust.
          Product Usage Statements
          Storage and Shipping Information
          Ship Code Ambient Temperature Only
          Toxicity Harmful
          Storage +2°C to +8°C
          Protect from Light Protect from light
          Hygroscopic Hygroscopic
          Do not freeze Ok to freeze
          Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
          Packaging Information
          Packaged under inert gas Packaged under inert gas
          Transport Information
          Supplemental Information
          Specifications

          Documentation

          Ficha datos de seguridad (MSDS)

          Título

          Ficha técnica de seguridad del material (MSDS) 

          Certificados de análisis

          CargoNúmero de lote
          3779

          Referencias bibliográficas

          Visión general referencias
          Robinson, A.J., and Dickerson, J.M. 2001. Br. J. Pharmacol. 133, 178.
          Izumi, H., et al. 1995. Am. J. Obstet. Gynecol. 172, 1477.
          Vannier, E., and Dinarello, C.A. 1994. J. Biol. Chem. 269, 9952.
          Yan, Q.Z., et al. 1994. Agents Actions 41, C111.
          Moncada, S., et al. 1991. Pharmacol. Rev. 43, 109.
          Bloom, F.E. 1990. in Pharmacological Basis of Therapeutics p. 224 (Gilman, A.G., et al., Eds.) Pergamon Press, New York.
          Ficha técnica

          Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

          Revision21-June-2011 JSW
          Synonyms2-(4-Imidazolyl)ethylamine
          DescriptionA potent vasodilator found in normal tissues and blood. Formed by the decarboxylation of L-histidine. Activates nitric oxide synthase (NOS), resulting in the release of nitric oxide. Activation of histamine H1 receptors leads to Ca2+ mobilization; whereas, histamine H2 receptor activation stimulates adenylate cyclase activity in neurons. Inhibits the synthesis of IL-2 and γ-IFN in peripheral blood mononuclear cells and lipopolysaccharide-induced synthesis of TNF-α in monocytes via H2 receptor activation.
          FormWhite solid
          Intert gas (Yes/No) Packaged under inert gas
          CAS number51-45-6
          RTECSMS1050000
          Chemical formulaC₅H₉N₃
          Structure formula
          Purity≥97% by TLC
          SolubilityH₂O (1 mg/ml)
          Storage +2°C to +8°C
          Protect from light
          Hygroscopic
          Do Not Freeze Ok to freeze
          Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
          Toxicity Harmful
          Merck USA index14, 4719
          ReferencesRobinson, A.J., and Dickerson, J.M. 2001. Br. J. Pharmacol. 133, 178.
          Izumi, H., et al. 1995. Am. J. Obstet. Gynecol. 172, 1477.
          Vannier, E., and Dinarello, C.A. 1994. J. Biol. Chem. 269, 9952.
          Yan, Q.Z., et al. 1994. Agents Actions 41, C111.
          Moncada, S., et al. 1991. Pharmacol. Rev. 43, 109.
          Bloom, F.E. 1990. in Pharmacological Basis of Therapeutics p. 224 (Gilman, A.G., et al., Eds.) Pergamon Press, New York.