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420134 | JNK Inhibitor VII, TAT-TI-JIP153-163, Cell-Permeable - Calbiochem

420134
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      Descripción

      Replacement Information

      Tabla espec. clave

      Empirical Formula
      C₁₂₅H₂₂₀N₅₂O₂₇

      Precios y disponibilidad

      Número de referenciaDisponiblidad Embalaje Cant./Env. Precio Cantidad
      US1420134-2MG
      Comprobando disponibilidad...
      Disponibilidad a confirmarDisponibilidad a confirmar
      En existencia 
      Suspendido
      Cantidades limitadas disponibles
      Debe confirmarse disponibilidad
        El resto: se avisará
          El resto: se avisará
          Se avisará
          Póngase en contacto con el Servicio de Atención al Cliente

          Frasco de vidrio 2 mg
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          Description
          OverviewThe non-permeant JNK inhibitor peptide TI-JIP153-163 (Cat. No. 420133) is made cell-permeable with an N-terminal TAT protein transduction domain sequence. Shown to offer neuroprotection in a rat ischemic brain injury model in in vivo.
          Catalogue Number420134
          Brand Family Calbiochem®
          SynonymsH₂N-YGRKKRRQRRR-RPKRPTTLNLF-NH₂, TAT₃₈₋₄₈ -Truncated Inhibitor based on JNK-Interacting Protein 1
          References
          ReferencesGuan, Q.H., et al. 2006. Neuroscience, 139, 609.
          Barr, R.K., et al. 2004. J. Biol. Chem. 279, 36327.
          Bogoyevitch, M.A., et al. 2003. Cell. Mol. Biol. Lett. 8, 550.
          Barr, R.K., et al. 2002. J. Biol. Chem. 277, 10987.
          Product Information
          ATP CompetitiveN
          FormLyophilized
          FormulationSupplied as a trifluoroacetate salt.
          Hill FormulaC₁₂₅H₂₂₀N₅₂O₂₇
          Chemical formulaC₁₂₅H₂₂₀N₅₂O₂₇
          Hygroscopic Hygroscopic
          ReversibleN
          Applications
          Biological Information
          Primary TargetJNK
          Purity≥97% by HPLC
          Physicochemical Information
          Cell permeableY
          Peptide SequenceH-Tyr-Gly-Arg-Lys-Lys-Arg-Arg-Gln-Arg-Arg-Arg-Arg-Pro-Lys-Arg-Pro-Thr-Thr-Leu-Asn-Leu-Phe-NH₂
          Dimensions
          Materials Information
          Toxicological Information
          Safety Information according to GHS
          Safety Information
          Product Usage Statements
          Storage and Shipping Information
          Ship Code Ambient Temperature Only
          Toxicity Standard Handling
          Storage +2°C to +8°C
          Protect from Light Protect from light
          Hygroscopic Hygroscopic
          Do not freeze Ok to freeze
          Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
          Packaging Information
          Packaged under inert gas Packaged under inert gas
          Transport Information
          Supplemental Information
          Specifications

          Documentation

          Ficha datos de seguridad (MSDS)

          Título

          Ficha técnica de seguridad del material (MSDS) 

          Certificados de análisis

          CargoNúmero de lote
          420134

          Referencias bibliográficas

          Visión general referencias
          Guan, Q.H., et al. 2006. Neuroscience, 139, 609.
          Barr, R.K., et al. 2004. J. Biol. Chem. 279, 36327.
          Bogoyevitch, M.A., et al. 2003. Cell. Mol. Biol. Lett. 8, 550.
          Barr, R.K., et al. 2002. J. Biol. Chem. 277, 10987.
          Ficha técnica

          Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

          Revision25-July-2008 RFH
          SynonymsH₂N-YGRKKRRQRRR-RPKRPTTLNLF-NH₂, TAT₃₈₋₄₈ -Truncated Inhibitor based on JNK-Interacting Protein 1
          DescriptionThe non-permeant JNK inhibitor peptide TI-JIP153-163 (Cat. No. 420133) is made cell-permeable with an N-terminal TAT protein transduction domain sequence. Shown to offer neuroprotection in a rat ischemic brain injury model in in vivo.
          FormLyophilized
          FormulationSupplied as a trifluoroacetate salt.
          Intert gas (Yes/No) Packaged under inert gas
          Chemical formulaC₁₂₅H₂₂₀N₅₂O₂₇
          Peptide SequenceH-Tyr-Gly-Arg-Lys-Lys-Arg-Arg-Gln-Arg-Arg-Arg-Arg-Pro-Lys-Arg-Pro-Thr-Thr-Leu-Asn-Leu-Phe-NH₂
          Purity≥97% by HPLC
          SolubilityDMSO (5 mg/ml) or H₂O (1 mg/ml)
          Storage +2°C to +8°C
          Protect from light
          Hygroscopic
          Do Not Freeze Ok to freeze
          Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
          Toxicity Standard Handling
          ReferencesGuan, Q.H., et al. 2006. Neuroscience, 139, 609.
          Barr, R.K., et al. 2004. J. Biol. Chem. 279, 36327.
          Bogoyevitch, M.A., et al. 2003. Cell. Mol. Biol. Lett. 8, 550.
          Barr, R.K., et al. 2002. J. Biol. Chem. 277, 10987.