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5677 | Spermine, Tetrahydrochloride - CAS 306-67-2 - Calbiochem

5677
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      Descripción

      Replacement Information

      Tabla espec. clave

      Empirical FormulaCAS #
      C₁₀H₂₆N₄ . 4HCl 306-67-2

      Precios y disponibilidad

      Número de referenciaDisponiblidad Embalaje Cant./Env. Precio Cantidad
      US15677-5GM
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      Disponibilidad a confirmarDisponibilidad a confirmar
      En existencia 
      Suspendido
      Cantidades limitadas disponibles
      Debe confirmarse disponibilidad
        El resto: se avisará
          El resto: se avisará
          Se avisará
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          Description
          OverviewPolyamine that plays an important role in the regulation of cellular proliferation and differentiation. Has both stimulatory and inhibitory effects on NMDA receptors depending on the subunit composition of the receptor. Acts as an inhibitor of phospholipase Cα and an activator of phospholipase Cδ. Inhibits DNA fragmentation and morphological apoptosis. Inhibits neuronal NOS.
          Catalogue Number5677
          Brand Family Calbiochem®
          References
          ReferencesIgarashi, K. and Williams, K. 1995. J. Pharmacol. Exp. Ther. 272, 1101.
          Escargueil-Blanc, I., et al. 1994. FASEB J. 8, 1075.
          Hu, J., et al. 1994. Neurosci. Lett. 175, 41.
          Tompkins, T.A. and Moscarello, M.A. 1994. Biochim. Biophys. Acta 1206, 1208.
          Trubiani, O., et al. 1994. Biochem. Mol. Biol. Int. 32, 1085.
          Svensson, F., et al. 1993. Mol. Cell. Biochem. 124, 141.
          Ask, A., et al. 1992. Cancer Lett. 66, 29.
          Chida, N., et al. 1992. Brain Res. 593, 57.
          Khan, A.U., et al. 1992. Proc. Natl. Acad. Sci. USA 89, 11428.
          Messena, L., et al. 1992. J. Leukoc. Biol. 52, 585.
          Pawelczyk, T., et al. 1992. Arch. Biochem. Biophys. 297, 328.
          Shantz, L.M., et al. 1992. Biochem. J. 288, 511.
          Product Information
          CAS number306-67-2
          FormWhite solid
          Hill FormulaC₁₀H₂₆N₄ . 4HCl
          Chemical formulaC₁₀H₂₆N₄ . 4HCl
          Structure formula Image
          Applications
          Biological Information
          Primary Targetphospholipase C α
          Secondary targetnNOS
          Purity≥99% by titration
          Physicochemical Information
          Dimensions
          Materials Information
          Toxicological Information
          Safety Information according to GHS
          RTECSEJ7230000
          Safety Information
          R PhraseR: 36/37/38

          Irritating to eyes, respiratory system and skin.
          S PhraseS: 26-36

          In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
          Wear suitable protective clothing.
          Product Usage Statements
          Storage and Shipping Information
          Ship Code Ambient Temperature Only
          Toxicity Irritant
          Storage +15°C to +30°C
          Do not freeze Ok to freeze
          Special InstructionsFollowing reconstitution, aliquot, purge with inert gas, and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C under inert gas.
          Packaging Information
          Transport Information
          Supplemental Information
          Specifications

          Documentation

          Ficha datos de seguridad (MSDS)

          Título

          Ficha técnica de seguridad del material (MSDS) 

          Certificados de análisis

          CargoNúmero de lote
          5677

          Referencias bibliográficas

          Visión general referencias
          Igarashi, K. and Williams, K. 1995. J. Pharmacol. Exp. Ther. 272, 1101.
          Escargueil-Blanc, I., et al. 1994. FASEB J. 8, 1075.
          Hu, J., et al. 1994. Neurosci. Lett. 175, 41.
          Tompkins, T.A. and Moscarello, M.A. 1994. Biochim. Biophys. Acta 1206, 1208.
          Trubiani, O., et al. 1994. Biochem. Mol. Biol. Int. 32, 1085.
          Svensson, F., et al. 1993. Mol. Cell. Biochem. 124, 141.
          Ask, A., et al. 1992. Cancer Lett. 66, 29.
          Chida, N., et al. 1992. Brain Res. 593, 57.
          Khan, A.U., et al. 1992. Proc. Natl. Acad. Sci. USA 89, 11428.
          Messena, L., et al. 1992. J. Leukoc. Biol. 52, 585.
          Pawelczyk, T., et al. 1992. Arch. Biochem. Biophys. 297, 328.
          Shantz, L.M., et al. 1992. Biochem. J. 288, 511.

          Folleto

          Cargo
          Excitotoxic Glutamate Analogs Technical Bulletin
          Ficha técnica

          Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

          Revision08-October-2007 JSW
          DescriptionPolyamine that plays an important role in the regulation of cellular proliferation and differentiation. Acts as an inhibitor of phopholipase C-α and an activator of phopholipase C-δ. Has both stimulatory and inhibitory effects on NMDA receptors depending on the subunit composition of the receptor. Inhibits neuronal NOS. Inhibits DNA fragmentation and morphological apoptosis.
          FormWhite solid
          CAS number306-67-2
          RTECSEJ7230000
          Chemical formulaC₁₀H₂₆N₄ . 4HCl
          Structure formula
          Purity≥99% by titration
          SolubilityH₂O (20 mg/ml)
          Storage +15°C to +30°C
          Do Not Freeze Ok to freeze
          Special InstructionsFollowing reconstitution, aliquot, purge with inert gas, and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C under inert gas.
          Toxicity Irritant
          Merck USA index14, 8743
          ReferencesIgarashi, K. and Williams, K. 1995. J. Pharmacol. Exp. Ther. 272, 1101.
          Escargueil-Blanc, I., et al. 1994. FASEB J. 8, 1075.
          Hu, J., et al. 1994. Neurosci. Lett. 175, 41.
          Tompkins, T.A. and Moscarello, M.A. 1994. Biochim. Biophys. Acta 1206, 1208.
          Trubiani, O., et al. 1994. Biochem. Mol. Biol. Int. 32, 1085.
          Svensson, F., et al. 1993. Mol. Cell. Biochem. 124, 141.
          Ask, A., et al. 1992. Cancer Lett. 66, 29.
          Chida, N., et al. 1992. Brain Res. 593, 57.
          Khan, A.U., et al. 1992. Proc. Natl. Acad. Sci. USA 89, 11428.
          Messena, L., et al. 1992. J. Leukoc. Biol. 52, 585.
          Pawelczyk, T., et al. 1992. Arch. Biochem. Biophys. 297, 328.
          Shantz, L.M., et al. 1992. Biochem. J. 288, 511.