A part of Merck

654380 | Tunicamycin, Streptomyces lysosuperficus - CAS 11089-65-9 - Calbiochem

654380
No pudo obtenerse el precio
La cantidad mínima tiene que ser múltiplo de
Al finalizar el pedido Más información
Ahorró ()
 
Solicitar precio
Disponibilidad a confirmarDisponibilidad a confirmar
En existencia 
Suspendido
Cantidades limitadas disponibles
Debe confirmarse disponibilidad
    El resto: se avisará
      El resto: se avisará
      Se avisará
      Póngase en contacto con el Servicio de Atención al Cliente
      Ver precios y disponibilidad
      Click To Print This Page

      Descripción

      Replacement Information

      Tabla espec. clave

      Empirical FormulaCAS #
      C₃₉H₆₄N₄O₁₆ 11089-65-9

      Precios y disponibilidad

      Número de referenciaDisponiblidad Embalaje Cant./Env. Precio Cantidad
      US1654380-10MG
      Comprobando disponibilidad...
      Disponibilidad a confirmarDisponibilidad a confirmar
      En existencia 
      Suspendido
      Cantidades limitadas disponibles
      Debe confirmarse disponibilidad
        El resto: se avisará
          El resto: se avisará
          Se avisará
          Póngase en contacto con el Servicio de Atención al Cliente

          Frasco de vidrio 10 mg
          Recuperando precio...
          No pudo obtenerse el precio
          La cantidad mínima tiene que ser múltiplo de
          Al finalizar el pedido Más información
          Ahorró ()
           
          Solicitar precio
          US1654380-50MG
          Comprobando disponibilidad...
          Disponibilidad a confirmarDisponibilidad a confirmar
          En existencia 
          Suspendido
          Cantidades limitadas disponibles
          Debe confirmarse disponibilidad
            El resto: se avisará
              El resto: se avisará
              Se avisará
              Póngase en contacto con el Servicio de Atención al Cliente

              Tambor de alum 50 mg
              Recuperando precio...
              No pudo obtenerse el precio
              La cantidad mínima tiene que ser múltiplo de
              Al finalizar el pedido Más información
              Ahorró ()
               
              Solicitar precio
              Description
              OverviewA nucleoside antibiotic that inhibits N-linked glycosylation and blocks the formation of N-glycosidic protein-carbohydrate linkages. Active in vitro against Gram-positive bacteria, yeasts, fungi, and viruses. Inhibits the expression of functional thrombin receptors on human T-lymphoblastoid cells. Also inhibits thrombin-induced Ca2+ mobilization in cells. Also available as a 25 mM solution in DMSO (Cat. No. 504570).
              Catalogue Number654380
              Brand Family Calbiochem®
              References
              ReferencesTordai, A., et al. 1995. Biochem. Biophys. Res. Commun. 206, 857.
              Price, B.D., et al. 1992. J. Cell Physiol. 152, 545.
              Product Information
              CAS number11089-65-9
              FormWhite to off-white solid
              Hill FormulaC₃₉H₆₄N₄O₁₆
              Chemical formulaC₃₉H₆₄N₄O₁₆
              ReconstitutionAqueous solutions can be prepared from stock solutions in DMSO by diluting with H₂O at pH 8.0 to 10.0 or with appropriate buffers at pH >7.0 (preferably >8.0).
              Structure formula Image
              Applications
              Biological Information
              Primary TargetN-linked glycosylation
              Secondary targetthrombin-induced Ca2+ mobilization in cells
              Purity≥98% by HPLC (A+B+C+D)
              Physicochemical Information
              Dimensions
              Materials Information
              Toxicological Information
              Safety Information according to GHS
              RTECSYO7980200
              Safety Information
              R PhraseR: 26/27/28-60-61

              Very toxic by inhalation, in contact with skin and if swallowed.
              May impair fertility.
              May cause harm to the unborn child.
              S PhraseS: 22-36/37/39-45

              Do not breathe dust.
              Wear suitable protective clothing, gloves and eye/face protection.
              In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible).
              Product Usage Statements
              Storage and Shipping Information
              Ship Code Ambient Temperature Only
              Toxicity Highly Toxic & Carcinogenic / Teratogenic
              Hazardous Materials Attention: Due to the nature of the Hazardous Materials in this shipment, additional shipping charges may be applied to your order. Certain sizes may be exempt from the additional hazardous materials shipping charges. Please contact your local sales office for more information regarding these charges.
              Storage +15°C to +30°C
              Do not freeze Ok to freeze
              Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 2 weeks at -20°C.
              Packaging Information
              Transport Information
              Supplemental Information
              Specifications

              Documentation

              Ficha datos de seguridad (MSDS)

              Título

              Ficha técnica de seguridad del material (MSDS) 

              Certificados de análisis

              CargoNúmero de lote
              654380

              Referencias bibliográficas

              Visión general referencias
              Tordai, A., et al. 1995. Biochem. Biophys. Res. Commun. 206, 857.
              Price, B.D., et al. 1992. J. Cell Physiol. 152, 545.

              Citas

              Título
            • Ray S. Oh, Xinli Bai and Johanna M. Rommens. (2006) Human homologs of UbC6P ubiquitin-conjugating enzyme and phosphorylation of HSUbC6E in response to endoplasmic reticulum stress. Journal of Biological Chemistry 281, 21480-21490.
            • Wolfdieter Springer, et al. (2005) A Caenorhabditis elegans Parkin mutant with altered solubility couples α-synuclein aggregation to proteotoxic stress. Human Molecular Genetics 14, 3407-3423.
            • Jenny J.L. Ho, et al. (2003) N-glycosylation is required for the surface localization of MUC17 mucin. 23, 585-592.
            • Ficha técnica

              Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

              Revision19-September-2007 RFH
              DescriptionA nucleoside antibiotic that inhibits N-linked glycosylation and blocks the formation of N-glycosidic protein-carbohydrate linkages. Active in vitro against gram-positive bacteria, yeasts, fungi, and viruses. Inhibits the expression of functional thrombin receptors on human T-lymphoblastoid cells. Also inhibits thrombin-induced Ca2+ mobilization in cells.
              FormWhite to off-white solid
              CAS number11089-65-9
              RTECSYO7980200
              Chemical formulaC₃₉H₆₄N₄O₁₆
              Structure formula
              Purity≥98% by HPLC (A+B+C+D)
              SolubilityDMSO (10 mg/ml), DMF, or Pyridine. Aqueous solutions can be prepared from DMSO stock solutions by diluting in H₂O at pH 8.0 to 10.0 or with appropriate buffers at pH >7.0.
              Storage +15°C to +30°C
              Do Not Freeze Ok to freeze
              Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 2 weeks at -20°C.
              Toxicity Highly Toxic & Carcinogenic / Teratogenic
              Merck USA index14, 9819
              ReferencesTordai, A., et al. 1995. Biochem. Biophys. Res. Commun. 206, 857.
              Price, B.D., et al. 1992. J. Cell Physiol. 152, 545.
              Citation
            • Ray S. Oh, Xinli Bai and Johanna M. Rommens. (2006) Human homologs of UbC6P ubiquitin-conjugating enzyme and phosphorylation of HSUbC6E in response to endoplasmic reticulum stress. Journal of Biological Chemistry 281, 21480-21490.
            • Wolfdieter Springer, et al. (2005) A Caenorhabditis elegans Parkin mutant with altered solubility couples α-synuclein aggregation to proteotoxic stress. Human Molecular Genetics 14, 3407-3423.
            • Jenny J.L. Ho, et al. (2003) N-glycosylation is required for the surface localization of MUC17 mucin. 23, 585-592.