05-23-0070 α-Helical Corticotropin Releasing Factor 9-41

05-23-0070
  
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      Přehled

      Replacement Information

      Tabulka spec. kláve

      Empirical FormulaCAS #
      C₁₆₆H₂₇₄N₄₆O₅₃S₂ 99658-03-4
      Description
      Overview

      This product has been discontinued.

      We apologize for the inconvenience, but we do not currently have an alternative product.






      A stable analog of porcine motilin with full biological activity. Acts as a potent antagonist of CRF receptors. Blocks stress-induced hypophagia and weight loss.
      Catalogue Number05-23-0070
      Brand Family Calbiochem®
      SynonymsCRF Antagonist; α-Helical CRF (9-41)
      References
      ReferencesSamgin, G.N., et al. 1999. Am. J. Physiol. 276, R1461.
      Moody, T.W., et al. 1994. Peptides 15, 281.
      Milton, N.G., et al. 1993. J. Physiol. 465, 415.
      Rivier, J., et al. 1984. Science 224, 889.
      Product Information
      CAS number99658-03-4
      FormWhite to off-white lyophilized solid
      Hill FormulaC₁₆₆H₂₇₄N₄₆O₅₃S₂
      Chemical formulaC₁₆₆H₂₇₄N₄₆O₅₃S₂
      Hygroscopic Hygroscopic
      Sold on the basis of peptide contentY
      Applications
      Biological Information
      Purity≥97% by HPLC
      Physicochemical Information
      Peptide ContentY
      Peptide SequenceH-Asp-Leu-Thr-Phe-His-Leu-Leu-Arg-Glu-Met-Leu-Glu-Met-Ala-Lys-Ala-Glu-Gln-Glu-Ala-Glu-Gln-Ala-Ala-Leu-Asn-Arg-Leu-Leu-Leu-Glu-Glu-Ala-NH₂
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Ambient Temperature Only
      Toxicity Standard Handling
      Storage -20°C
      Hygroscopic Hygroscopic
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstitution aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
      Packaging Information
      Transport Information
      Supplemental Information
      Specifications

      Documentation

      MSDS

      Title

      Safety Data Sheet (SDS) 

      Certificates of Analysis

      TitleLot Number
      05-23-0070

      References

      Přehled odkazů
      Samgin, G.N., et al. 1999. Am. J. Physiol. 276, R1461.
      Moody, T.W., et al. 1994. Peptides 15, 281.
      Milton, N.G., et al. 1993. J. Physiol. 465, 415.
      Rivier, J., et al. 1984. Science 224, 889.
      Data Sheet

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision12-May-2008 JSW
      SynonymsCRF Antagonist; α-Helical CRF (9-41)
      DescriptionAn analog of corticotropin-releasing factor that acts as a potent and competetive antagonist of CRF receptors.
      FormWhite to off-white lyophilized solid
      CAS number99658-03-4
      Chemical formulaC₁₆₆H₂₇₄N₄₆O₅₃S₂
      Peptide SequenceH-Asp-Leu-Thr-Phe-His-Leu-Leu-Arg-Glu-Met-Leu-Glu-Met-Ala-Lys-Ala-Glu-Gln-Glu-Ala-Glu-Gln-Ala-Ala-Leu-Asn-Arg-Leu-Leu-Leu-Glu-Glu-Ala-NH₂
      Purity≥97% by HPLC
      Solubility5% acetic acid (5 mg/ml)
      Storage -20°C
      Hygroscopic
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing reconstitution aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
      Toxicity Standard Handling
      ReferencesSamgin, G.N., et al. 1999. Am. J. Physiol. 276, R1461.
      Moody, T.W., et al. 1994. Peptides 15, 281.
      Milton, N.G., et al. 1993. J. Physiol. 465, 415.
      Rivier, J., et al. 1984. Science 224, 889.