114700 | Activin A, Human, Recombinant, CHO Cells

114700
No pudo obtenerse el precio
La cantidad mínima tiene que ser múltiplo de
Al finalizar el pedido Más información
Ahorró ()
 
Solicitar precio
Disponibilidad a confirmarDisponibilidad a confirmar
En existencia 
Suspendido
Cantidades limitadas disponibles
Debe confirmarse disponibilidad
    El resto: se avisará
      El resto: se avisará
      Se avisará
      Póngase en contacto con el Servicio de Atención al Cliente
      Ver precios y disponibilidad
      Click To Print This Page

      Descripción

      Replacement Information

      Tabla espec. clave

      Purity
      ≥95% by SDS-PAGE

      Precios y disponibilidad

      Número de referenciaDisponiblidad Embalaje Cant./Env. Precio Cantidad
      114700-10UG
      Comprobando disponibilidad...
      Disponibilidad a confirmarDisponibilidad a confirmar
      En existencia 
      Suspendido
      Cantidades limitadas disponibles
      Debe confirmarse disponibilidad
        El resto: se avisará
          El resto: se avisará
          Se avisará
          Póngase en contacto con el Servicio de Atención al Cliente

          Ampolla de plást. 10 μg
          Recuperando precio...
          No pudo obtenerse el precio
          La cantidad mínima tiene que ser múltiplo de
          Al finalizar el pedido Más información
          Ahorró ()
           
          Solicitar precio
          Description
          OverviewRecombinant, human activin A (disulfide-linked homodimer of two 116-amino acid residue βA subunits) expressed in CHO cells. Mature βA-monomer lacks a potential N-linked glycosylation site and has a calculated molecular weight of 13 kDa. A member of the TGF-β superfamily that is involved in the negative regulation of B lineage lymphocytes. Shown to play an important role in the regulation of hormonogenesis, cellular homeostasis, and differentiation programs. Reported to inhibit endogenous production of IL-6.
          Catalogue Number114700
          Brand Family Calbiochem®
          References
          ReferencesZipori, D., et al. 2001. J. Leukoc. Biol. 69, 867.
          Hedger, M.P., et al. 2000. Cytokine 12, 595.
          Woodruff, T.K. 1998. Biochem. Pharmacol. 55, 953.
          Ying, S.Y., et al. 1997. Proc. Soc. Exp. Biol. Med. 214, 114.
          Schwall, R.H., and Lei, C. 1991. Methods Enzymol. 198, 340.
          Mason, A., et al. 1986. Biochem. Biophys. Res. Commun. 135, 957.
          Product Information
          FormLyophilized
          FormulationLyophilized from sterile filtered 35% acetonitrile, 0.1% TFA, 50 µg BSA/µg Activin A.
          Applications
          Biological Information
          Biological activityED₅₀ = 0.5-2.0 ng/ml as measured by its ability to induce hemoglobin expression in K562 cells
          Purity≥95% by SDS-PAGE
          Physicochemical Information
          ContaminantsEndotoxin: ≤100 pg/µg Activin A
          Dimensions
          Materials Information
          Toxicological Information
          Safety Information according to GHS
          Safety Information
          Product Usage Statements
          Storage and Shipping Information
          Ship Code Ambient Temperature Only
          Toxicity Standard Handling
          Storage ≤ -70°C
          Do not freeze Ok to freeze
          Special InstructionsFollowing reconstitution, aliquot and freeze (-70°C). Stock solutions are stable for up to 3 months at -70°C. Avoid freeze/thaw cycles of solutions.
          Packaging Information
          Transport Information
          Supplemental Information
          Specifications

          Documentation

          Ficha datos de seguridad (MSDS)

          Título

          Ficha técnica de seguridad del material (MSDS) 

          Certificados de análisis

          CargoNúmero de lote
          114700

          Referencias bibliográficas

          Visión general referencias
          Zipori, D., et al. 2001. J. Leukoc. Biol. 69, 867.
          Hedger, M.P., et al. 2000. Cytokine 12, 595.
          Woodruff, T.K. 1998. Biochem. Pharmacol. 55, 953.
          Ying, S.Y., et al. 1997. Proc. Soc. Exp. Biol. Med. 214, 114.
          Schwall, R.H., and Lei, C. 1991. Methods Enzymol. 198, 340.
          Mason, A., et al. 1986. Biochem. Biophys. Res. Commun. 135, 957.

          Folleto

          Cargo
          Growth Factors and Cytokines Technical Bulletin
          Ficha técnica

          Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

          Revision07-April-2008 RFH
          DescriptionRecombinant, human activin A (disulfide-linked homodimer of two 116-amino acid residue βA subunits) expressed in CHO cells. Mature βA-monomer lacks a potential N-linked glycosylation site and has a calculated molecular mass of 13 kDa. Activins are members of the TGF-β superfamily and have been shown to play an important role in the regulation of homonogenesis, cellular homeostasis, and differentiation programs.
          FormLyophilized
          FormulationLyophilized from sterile filtered 35% acetonitrile, 0.1% TFA, 50 µg BSA/µg Activin A.
          Purity≥95% by SDS-PAGE
          ContaminantsEndotoxin: ≤100 pg/µg Activin A
          Biological activityED₅₀ = 0.5-2.0 ng/ml as measured by its ability to induce hemoglobin expression in K562 cells
          SolubilityReconstitute to a concentration ≥10 µg/ml with sterile PBS containing ≥0.1% HSA or BSA.
          Storage ≤ -70°C
          Do Not Freeze Ok to freeze
          Special InstructionsFollowing reconstitution, aliquot and freeze (-70°C). Stock solutions are stable for up to 3 months at -70°C. Avoid freeze/thaw cycles of solutions.
          Toxicity Standard Handling
          ReferencesZipori, D., et al. 2001. J. Leukoc. Biol. 69, 867.
          Hedger, M.P., et al. 2000. Cytokine 12, 595.
          Woodruff, T.K. 1998. Biochem. Pharmacol. 55, 953.
          Ying, S.Y., et al. 1997. Proc. Soc. Exp. Biol. Med. 214, 114.
          Schwall, R.H., and Lei, C. 1991. Methods Enzymol. 198, 340.
          Mason, A., et al. 1986. Biochem. Biophys. Res. Commun. 135, 957.