Attention: We have moved. Merck Millipore products are no longer available for purchase on MerckMillipore.com.Learn More

164605 Aminopeptidase N (CD13), Human Serum

164605
Purchase on Sigma-Aldrich

Descripción

Replacement Information

Tabla espec. clave

Products

Número de referenciaEmbalaje Cant./Env.
164605-10UG Ampolla de plást. 10 μg
Description
OverviewNative aminopeptidase N purified from human serum. Aminopeptidase N is a single-chain, integral membrane protease with broad specificity that functions to remove N-terminal amino acids from peptides. It also acts as a receptor for coronavirus and is known to play a role in angiogenesis, HIV entry, and in degradation of extracellular matrix as a result of tumor invasion.
Catalogue Number164605
Brand Family Calbiochem®
SynonymsAPN/CD13, Aminopeptidase N
References
ReferencesBhagwat, S.V., et al. 2003. Blood 101, 1818.
Kawai, M., et al. 2001. Clin. Chem. 47, 223.
Watanabe, Y., et al. 1998. Mol. Genet. Metab. 63, 289.
Pulido-Cejudo, G., et al. 1997. Antiviral Res. 36, 167.
Hansen, A.S., et al. 1993. Eur. J. Immunol. 23, 2358.
Saiki, I., et al. 1993. Int. J. Cancer 54,137.
Shipp, M.A. and Look, A.T. 1993. Blood 82, 1052.
Yeager, C.L., et al. 1992. Nature 357, 420.
Product Information
Unit of DefinitionOne unit is defined as the amount of enzyme that will hydrolyze 1.0 µmol L-leucine-p-nitroanilide) per min at 37°C, pH 7.2.
EC number3.4.11.2
FormLiquid
FormulationIn 150 mM NaCl, 50 mM Tris-HCl, 1 mM CaCl₂, pH 8.0.
Applications
Biological Information
Purity≥92% by SDS-PAGE
SourcePrepared from human serum that has been shown by certified tests to be negative for HBsAg and for antibodies to HIV and HCV.
Specific Activity≥450 mU/mg protein
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Storage and Shipping Information
Ship Code Dry Ice Only
Toxicity Standard Handling
Storage ≤ -70°C
Avoid freeze/thaw Avoid freeze/thaw
Do not freeze Ok to freeze
Special InstructionsFollowing initial thaw, aliquot and freeze (-70°C).
Packaging Information
Transport Information
Supplemental Information
Specifications

Documentation

Aminopeptidase N (CD13), Human Serum Certificados de análisis

CargoNúmero de lote
164605

Referencias bibliográficas

Visión general referencias
Bhagwat, S.V., et al. 2003. Blood 101, 1818.
Kawai, M., et al. 2001. Clin. Chem. 47, 223.
Watanabe, Y., et al. 1998. Mol. Genet. Metab. 63, 289.
Pulido-Cejudo, G., et al. 1997. Antiviral Res. 36, 167.
Hansen, A.S., et al. 1993. Eur. J. Immunol. 23, 2358.
Saiki, I., et al. 1993. Int. J. Cancer 54,137.
Shipp, M.A. and Look, A.T. 1993. Blood 82, 1052.
Yeager, C.L., et al. 1992. Nature 357, 420.
Ficha técnica

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision06-September-2007 RFH
SynonymsAPN/CD13, Aminopeptidase N
DescriptionNative aminopeptidase N purified from human serum. Aminopeptidase N is a single-chain, integral membrane protease with broad specificity that functions to remove N-terminal amino acids from peptides. It also acts as a receptor for coronavirus and is known to play a role in angiogenesis, HIV entry, and in degradation of extracellular matrix as a result of tumor invasion. Activity is inhibited by amastatin, actinonin, and bestatin (Cat. No. 200484) (~150 µM).
FormLiquid
FormulationIn 150 mM NaCl, 50 mM Tris-HCl, 1 mM CaCl₂, pH 8.0.
SourcePrepared from human serum that has been shown by certified tests to be negative for HBsAg and for antibodies to HIV and HCV.
EC number3.4.11.2
Purity≥92% by SDS-PAGE
Specific activity≥450 mU/mg protein
Unit definitionOne unit is defined as the amount of enzyme that will hydrolyze 1.0 µmol L-leucine-p-nitroanilide) per min at 37°C, pH 7.2.
Storage ≤ -70°C
Avoid freeze/thaw
Do Not Freeze Ok to freeze
Special InstructionsFollowing initial thaw, aliquot and freeze (-70°C).
Toxicity Standard Handling
ReferencesBhagwat, S.V., et al. 2003. Blood 101, 1818.
Kawai, M., et al. 2001. Clin. Chem. 47, 223.
Watanabe, Y., et al. 1998. Mol. Genet. Metab. 63, 289.
Pulido-Cejudo, G., et al. 1997. Antiviral Res. 36, 167.
Hansen, A.S., et al. 1993. Eur. J. Immunol. 23, 2358.
Saiki, I., et al. 1993. Int. J. Cancer 54,137.
Shipp, M.A. and Look, A.T. 1993. Blood 82, 1052.
Yeager, C.L., et al. 1992. Nature 357, 420.