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195111 Anti-BACE1, C-Terminal (485-501) Rabbit pAb

195111
Purchase on Sigma-Aldrich

Descripción

Replacement Information

Tabla espec. clave

Species ReactivityHostAntibody Type
H, M, R Rb Polyclonal Antibody

Products

Número de referenciaEmbalaje Cant./Env.
195111-100UL Ampolla de plást. 100 ul
Description
OverviewRecognizes both the immature and mature forms of the BACE1 protein.
Catalogue Number195111
Brand Family Calbiochem®
SynonymsAnti-B690
References
ReferencesYan, R., et al. 2001. J. Biol. Chem. 276, 36788.
Product Information
FormLiquid
FormulationUndiluted serum.
PreservativeNone
Applications
Key Applications Immunoprecipitation
Radioimmunoassay
Immunoblotting (Western Blotting)
Immunofluorescence
Immunohistochemistry
Application NotesImmunoblotting (1:500-1:1000)
Immunofluorescence (1:200)
Immunohistochemistry (see comments)
Immunoprecipitation (3 µl/reaction)
Radioimmunoassay (3-5 µl/reaction)
Application CommentsThis antibody is also reported to work for immunohistochemistry. Variables associated with assay conditions will dictate the optimal working dilution.
Biological Information
Immunogena synthetic peptide (CLRQQHDDFADDISLLK) corresponding to amino acids 485-501 of human BACE1, conjugated to KLH
ImmunogenHuman
HostRabbit
IsotypeIgG
Species Reactivity
  • Human
  • Mouse
  • Rat
Antibody TypePolyclonal Antibody
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Storage and Shipping Information
Ship Code Dry Ice Only
Toxicity Standard Handling
Storage -20°C
Avoid freeze/thaw Avoid freeze/thaw
Do not freeze Ok to freeze
Special InstructionsFollowing initial thaw, aliquot and freeze (-20°C).
Packaging Information
Transport Information
Supplemental Information
Specifications

Documentation

Anti-BACE1, C-Terminal (485-501) Rabbit pAb Ficha datos de seguridad (MSDS)

Título

Ficha técnica de seguridad del material (MSDS) 

Anti-BACE1, C-Terminal (485-501) Rabbit pAb Certificados de análisis

CargoNúmero de lote
195111

Referencias bibliográficas

Visión general referencias
Yan, R., et al. 2001. J. Biol. Chem. 276, 36788.

Folleto

Cargo
Alzheimer's Disease Brochure & Technical Guide
Ficha técnica

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision27-June-2007 RFH
SynonymsAnti-B690
ApplicationImmunoblotting (1:500-1:1000)
Immunofluorescence (1:200)
Immunohistochemistry (see comments)
Immunoprecipitation (3 µl/reaction)
Radioimmunoassay (3-5 µl/reaction)
DescriptionRabbit polyclonal antibody supplied as undiluted serum. Recognizes both the immature and mature forms of BACE1.
Backgroundβ-secretase has been identified as a novel membrane-bound aspartyl protease named BACE1 (β-site amyloid precursor protein cleaving enzyme 1). It is one of two endopeptidases that cleave the β-amyloid precursor protein (APP) resulting in the accumulation of the β-amyloid deposits involved in the development of Alzheimer's disease.
HostRabbit
Immunogen speciesHuman
Immunogena synthetic peptide (CLRQQHDDFADDISLLK) corresponding to amino acids 485-501 of human BACE1, conjugated to KLH
IsotypeIgG
Specieshuman, mouse, rat
FormLiquid
FormulationUndiluted serum.
PreservativeNone
CommentsThis antibody is also reported to work for immunohistochemistry. Variables associated with assay conditions will dictate the optimal working dilution.
Storage -20°C
Avoid freeze/thaw
Do Not Freeze Ok to freeze
Special InstructionsFollowing initial thaw, aliquot and freeze (-20°C).
Toxicity Standard Handling
ReferencesYan, R., et al. 2001. J. Biol. Chem. 276, 36788.