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203408 BLEOCIN™ Antibiotic, Streptomyces verticillus, Cell Culture-Tested - CAS 55658-47-4 - Calbiochem

203408
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Descripción

Replacement Information

Tabla espec. clave

Empirical FormulaCAS #
C₅₇H₈₉CuN₁₉O₂₁S₂ · 3HCl 55658-47-4

Products

Número de referenciaEmbalaje Cant./Env.
203408-100MG Ampolla de plást. 100 mg
203408-10MG Ampolla de plást. 10 mg
203408-250MG Ampolla de plást. 250 mg
Description
OverviewA unique antibiotic of the bleomycin family that is toxic to eukaryotic and prokaryotic cells. BLEOCIN™ Antibiotic cleaves double-stranded DNA and inhibits DNA synthesis, resulting in cell death. Can be used for selection of recombinant clones in a variety of cell types transfected with vectors containing a ble resistance marker. Copper content: ≥3.5%. Potency: ≥750 µg/mg.
Catalogue Number203408
Brand Family Calbiochem®
References
ReferencesSergeev, D.S., et al. 1995. Bioorg. Khim. 21, 695.
Mulsant, P., et al. 1988. Somatic Cell and Molecular Genetics 14, 243.
Ehrenfeld, G.M., et al. 1987. Biochemistry 26, 931.
Takita, T., et al. 1972. J. Antibiot. 25, 755.
Product Information
CAS number55658-47-4
FormBlue lyophilized solid
Hill FormulaC₅₇H₈₉CuN₁₉O₂₁S₂ · 3HCl
Chemical formulaC₅₇H₈₉CuN₁₉O₂₁S₂ · 3HCl
Hygroscopic Hygroscopic
Structure formula ImageStructure formula Image
Applications
Biological Information
Purity≥85% by HPLC
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
RTECSEC5990700
Safety Information
R PhraseR: 20/21/22-36/37/38-40-42/43

Harmful by inhalation, in contact with skin and if swallowed.
Irritating to eyes, respiratory system and skin.
Limited evidence of a carcinogenic effect.
May cause sensitization by inhalation and skin contact.
S PhraseS: 22-26-36/37/39-45

Do not breathe dust.
In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
Wear suitable protective clothing, gloves and eye/face protection.
In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible).
Product Usage Statements
Storage and Shipping Information
Ship Code Ambient Temperature Only
Toxicity Harmful & Carcinogenic / Teratogenic
Storage +2°C to +8°C
Protect from Light Protect from light
Hygroscopic Hygroscopic
Do not freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 1 year at -20°C.
Packaging Information
Transport Information
Supplemental Information
Specifications

Documentation

BLEOCIN™ Antibiotic, Streptomyces verticillus, Cell Culture-Tested - CAS 55658-47-4 - Calbiochem Ficha datos de seguridad (MSDS)

Título

Ficha técnica de seguridad del material (MSDS) 

BLEOCIN™ Antibiotic, Streptomyces verticillus, Cell Culture-Tested - CAS 55658-47-4 - Calbiochem Certificados de análisis

CargoNúmero de lote
203408

Referencias bibliográficas

Visión general referencias
Sergeev, D.S., et al. 1995. Bioorg. Khim. 21, 695.
Mulsant, P., et al. 1988. Somatic Cell and Molecular Genetics 14, 243.
Ehrenfeld, G.M., et al. 1987. Biochemistry 26, 931.
Takita, T., et al. 1972. J. Antibiot. 25, 755.

Folleto

Cargo
Antibiotics Profiler
BLEOCIN Technical Bulletin
Ficha técnica

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision26-September-2007 RFH
DescriptionA unique antibiotic of the bleomycin family that is toxic to eukaryotic and prokaryotic cells. BLEOCIN™ cleaves double-stranded DNA and inhibits DNA synthesis, resulting in cell death. Can be used for selection of recombinant clones in a variety of cell types transfected with vectors containing a ble resistance marker. Copper content: ≥3.5%. Potency: ≥750 µg/mg.
FormBlue lyophilized solid
CAS number55658-47-4
RTECSEC5990700
Chemical formulaC₅₇H₈₉CuN₁₉O₂₁S₂ · 3HCl
Structure formulaStructure formula
Purity≥85% by HPLC
SolubilityH₂O (10 mg/ml)
Storage +2°C to +8°C
Hygroscopic
Protect from light
Do Not Freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 1 year at -20°C.
Toxicity Harmful & Carcinogenic / Teratogenic
ReferencesSergeev, D.S., et al. 1995. Bioorg. Khim. 21, 695.
Mulsant, P., et al. 1988. Somatic Cell and Molecular Genetics 14, 243.
Ehrenfeld, G.M., et al. 1987. Biochemistry 26, 931.
Takita, T., et al. 1972. J. Antibiot. 25, 755.