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236608 C-Reactive Protein, Human, Recombinant, E. coli

236608
Purchase on Sigma-Aldrich

Descripción

Replacement Information

Products

Número de referenciaEmbalaje Cant./Env.
236608-1MG Ampolla de plást. 1 mg
Description
OverviewRecombinant, human C-reactive protein expressed in E. coli. CRP is a major acute-phase plasma protein that is dramatically elevated in patients with acute-phase conditions. Composed of five identical noncovalently linked subunits. Exhibits Ca2+-dependent binding to a variety of substrates. Important in diagnosis of rheumatoid arthritis. Suitable for immunological studies. In purified states and in plasma the monomeric form (M.W. ~21 kDa) aggregates as a cyclic pentamer.
M.W. 23,000 (monomer); 115,000 (pentamer).
Catalogue Number236608
Brand Family Calbiochem®
SynonymsrhCRP
References
ReferencesPaffen, E., et al. 2004. Arterioscler. Thromb. Vasc. Biol. 24, 975.
Ballou, S.P., and Kushner, I. 1992. Adv. Intern. Med. 37, 313.
Stults, N.L., et al. 1987. Anal. Biochem. 161, 567.
Woo, P., et al. 1985. J. Biol. Chem. 260, 13384.
de Beer, F.C., and Pepys, M.B. 1982. J. Immun. Methods 50, 17.
Product Information
CAS number9007-41-4
FormLiquid
FormulationIn 140 mM NaCl, 20 mM Tris-HCl, 2 mM CaCl₂, 0.05% NaN₃, pH 7.5.
Applications
Biological Information
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Storage and Shipping Information
Ship Code Blue Ice Only
Toxicity Standard Handling
Storage +2°C to +8°C
Do not freeze Yes
Packaging Information
Transport Information
Supplemental Information
Specifications

Documentation

C-Reactive Protein, Human, Recombinant, E. coli Ficha datos de seguridad (MSDS)

Título

Ficha técnica de seguridad del material (MSDS) 

C-Reactive Protein, Human, Recombinant, E. coli Certificados de análisis

CargoNúmero de lote
236608

Referencias bibliográficas

Visión general referencias
Paffen, E., et al. 2004. Arterioscler. Thromb. Vasc. Biol. 24, 975.
Ballou, S.P., and Kushner, I. 1992. Adv. Intern. Med. 37, 313.
Stults, N.L., et al. 1987. Anal. Biochem. 161, 567.
Woo, P., et al. 1985. J. Biol. Chem. 260, 13384.
de Beer, F.C., and Pepys, M.B. 1982. J. Immun. Methods 50, 17.

Citas

Título
  • Paramita Baruah, et al. (2006) The pattern recognition receptor PTX3 is recruited at the synapse between dying and dendritic cells and edits the cross-presentation of self, viral and tumor antigens. Blood 107, 151-158.
  • Elaine Paffen, Hans L. Vos and Rogier M. Bertina. (2004) C-Reactive Protein Does Not Directly Induce Tissue Factor in Human Monocytes. Arteriosclerosis, Thrombosis, and Vascular Biology 24, 975-981.
  • Ficha técnica

    Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

    Revision13-February-2014 JSW
    SynonymsrhCRP
    DescriptionRecombinant, human C-reactive protein expressed in E. coli. CRP is a major acute-phase plasma protein that is dramatically elevated in patients with acute-phase conditions. Composed of five identical noncovalently linked subunits. Exhibits Ca2+-dependent binding to a variety of substrates. Important in diagnosis of rheumatoid arthritis. Suitable for immunological studies. In purified states and in plasma the monomeric form (M.W. ~21 kDa) aggregates as a cyclic pentamer. Intended for use as a calibration standard for assays of CRP, for structural and functional studies, and as an antigen for production of antisera. Calibrated by electroimmunoassay against WHO reference standard or equivalent.
    FormLiquid
    FormulationIn 140 mM NaCl, 20 mM Tris-HCl, 2 mM CaCl₂, 0.05% NaN₃, pH 7.5.
    CAS number9007-41-4
    SolubilityAqueous buffers
    Storage +2°C to +8°C
    Do Not Freeze Yes
    Toxicity Standard Handling
    Merck USA index14, 2603
    ReferencesPaffen, E., et al. 2004. Arterioscler. Thromb. Vasc. Biol. 24, 975.
    Ballou, S.P., and Kushner, I. 1992. Adv. Intern. Med. 37, 313.
    Stults, N.L., et al. 1987. Anal. Biochem. 161, 567.
    Woo, P., et al. 1985. J. Biol. Chem. 260, 13384.
    de Beer, F.C., and Pepys, M.B. 1982. J. Immun. Methods 50, 17.
    Citation
  • Paramita Baruah, et al. (2006) The pattern recognition receptor PTX3 is recruited at the synapse between dying and dendritic cells and edits the cross-presentation of self, viral and tumor antigens. Blood 107, 151-158.
  • Elaine Paffen, Hans L. Vos and Rogier M. Bertina. (2004) C-Reactive Protein Does Not Directly Induce Tissue Factor in Human Monocytes. Arteriosclerosis, Thrombosis, and Vascular Biology 24, 975-981.