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208690 Calmodulin, Bovine Brain

208690
Purchase on Sigma-Aldrich

Descripción

Replacement Information

Products

Número de referenciaEmbalaje Cant./Env.
208690-1MG Ampolla de plást. 1 mg
208690-5MG Frasco de vidrio 5 mg
Description
OverviewA ubiquitous Ca2+-binding protein that serves as a physiological effector of a wide range of biological processes. Calmodulin purified from bovine brain.
Note: 1 KU = 1000 units.
Note: this product cannot be used for animal treatment, in vivo research, or any contact procedure with livestock.
Catalogue Number208690
Brand Family Calbiochem®
SynonymsCaM, Ca2+/Calmodulin
References
ReferencesCarl, A., et al. 1990. J. Physiol. 429, 205.
Appleman, M.M., et al. 1985. J. Cyclic Nucleotide and Protein Phosph. Res. 10, 417.
Cheung, W.T. 1979. Science 207, 19.
Sharma, R.K., and Wang, J.H. 1979. Adv. Cyclic Nucleotide Res. 10, 187.
Wang, J.H., and Waisman, D.M. 1979. Curr. Topics Cell. Reg. 15, 47.
Watterson, A., et al. 1976. J. Biol. Chem. 251, 4501.
Product Information
CAS number73298-54-1
Unit of DefinitionOne unit is defined as the amount of calmodulin that gives rise to 50% of the maximal enzyme activation of a standard level of activator-deficient 3ʹ,5ʹ-cyclic nucleotide phosphodiesterase.
FormLyophilized
FormulationLyophilized from 150 mM NaCl, 50 mM Tris-HCl, 2 mM EDTA, pH 7.6.
Applications
Biological Information
Purity≥95% by SDS-PAGE
Specific Activity≥12,500 units/mg protein
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Storage and Shipping Information
Ship Code Ambient Temperature Only
Toxicity Standard Handling
Storage -20°C
Do not freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C or -70°C). Stock solutions are stable for up to 2 months at -20°C or for up to 4 months at -70°C.
Packaging Information
Transport Information
Supplemental Information
Specifications

Documentation

Calmodulin, Bovine Brain Ficha datos de seguridad (MSDS)

Título

Ficha técnica de seguridad del material (MSDS) 

Calmodulin, Bovine Brain Certificados de análisis

CargoNúmero de lote
208690

Referencias bibliográficas

Visión general referencias
Carl, A., et al. 1990. J. Physiol. 429, 205.
Appleman, M.M., et al. 1985. J. Cyclic Nucleotide and Protein Phosph. Res. 10, 417.
Cheung, W.T. 1979. Science 207, 19.
Sharma, R.K., and Wang, J.H. 1979. Adv. Cyclic Nucleotide Res. 10, 187.
Wang, J.H., and Waisman, D.M. 1979. Curr. Topics Cell. Reg. 15, 47.
Watterson, A., et al. 1976. J. Biol. Chem. 251, 4501.

Folleto

Cargo
Calmodulin and Related Products Technical Bulletin
Ficha técnica

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision10-February-2010 JSW
SynonymsCaM, Ca2+/Calmodulin
DescriptionA ubiquitous Ca2+-binding protein distributed in eukaryotic cells that serves as a major physiological effector for a wide range of cellular responses. The Ca2+-calmodulin complex is involved in the maintenance of intracellular Ca2+ homeostasis, as well as in the regulation of the intracellular concentration of other second messengers, such as cyclic AMP and inositol trisphosphate. Calmodulin purified from bovine brain.

Note: This product is not to be used for animal treatment, in vivo research or in any other contact procedure with livestock.
FormLyophilized
FormulationLyophilized from 150 mM NaCl, 50 mM Tris-HCl, 2 mM EDTA, pH 7.6.
CAS number73298-54-1
Purity≥95% by SDS-PAGE
Specific activity≥12,500 units/mg protein
Unit definitionOne unit is defined as the amount of calmodulin that gives rise to 50% of the maximal enzyme activation of a standard level of activator-deficient 3ʹ,5ʹ-cyclic nucleotide phosphodiesterase.
SolubilityAqueous buffers or H₂O
Storage -20°C
Do Not Freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C or -70°C). Stock solutions are stable for up to 2 months at -20°C or for up to 4 months at -70°C.
Toxicity Standard Handling
Merck USA index14, 1719
ReferencesCarl, A., et al. 1990. J. Physiol. 429, 205.
Appleman, M.M., et al. 1985. J. Cyclic Nucleotide and Protein Phosph. Res. 10, 417.
Cheung, W.T. 1979. Science 207, 19.
Sharma, R.K., and Wang, J.H. 1979. Adv. Cyclic Nucleotide Res. 10, 187.
Wang, J.H., and Waisman, D.M. 1979. Curr. Topics Cell. Reg. 15, 47.
Watterson, A., et al. 1976. J. Biol. Chem. 251, 4501.