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208698 Calmodulin, Human Brain

208698
Purchase on Sigma-Aldrich

Descripción

Replacement Information

Products

Número de referenciaEmbalaje Cant./Env.
208698-500UG Ampolla de plást. 500 μg
Description
OverviewCalmodulin purifed from human brain.
Catalogue Number208698
Brand Family Calbiochem®
SynonymsCaM, Ca2+/Calmodulin
References
ReferencesO'Neil, K.T., and DeGrado, W.F. 1990. Trends Pharmacol. Sci. 15, 59.
Gopalakrishna, R., and Anderson, W.B. 1982. Biochem. Biophys. Res. Commun. 104, 830.
Sharma, R.K., and Wang, J.H. 1979. Adv. Cyclic Nucleotide Res. 10, 187.
Product Information
Unit of DefinitionOne unit is defined as the amount of calmodulin that will give rise to 50% of the maximal enzyme activation of a standard level of activator-deficient 3ʹ,5ʹ-cyclic nucleotide phosphodiesterase.
FormLyophilized
FormulationLyophilized from protein solution with 2 mM EDTA.
Applications
Biological Information
Purity≥95% by Native PAGE
SourcePrepared from tissue of individuals that have been shown by certified tests to be negative for HBsAg and for antibodies to HIV and HCV.
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Storage and Shipping Information
Ship Code Ambient Temperature Only
Toxicity Standard Handling
Storage -20°C
Do not freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C or -70°C). Aqueous stock solutions are stable for up to 2 months at -20°C or for up to 4 months at -70°C.
Packaging Information
Transport Information
Supplemental Information
Specifications

Documentation

Calmodulin, Human Brain Ficha datos de seguridad (MSDS)

Título

Ficha técnica de seguridad del material (MSDS) 

Calmodulin, Human Brain Certificados de análisis

CargoNúmero de lote
208698

Referencias bibliográficas

Visión general referencias
O'Neil, K.T., and DeGrado, W.F. 1990. Trends Pharmacol. Sci. 15, 59.
Gopalakrishna, R., and Anderson, W.B. 1982. Biochem. Biophys. Res. Commun. 104, 830.
Sharma, R.K., and Wang, J.H. 1979. Adv. Cyclic Nucleotide Res. 10, 187.

Folleto

Cargo
Calmodulin and Related Products Technical Bulletin
Ficha técnica

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision28-May-2008 RFH
SynonymsCaM, Ca2+/Calmodulin
DescriptionCalmodulin purifed from human brain. Calmodulin is a ubiquitous Ca2+-binding protein distributed in eukaryotic cells that serves as a major physiological effector for a wide range of cellular responses. The Ca2+-calmodulin complex is involved in the maintenance of intracellular Ca2+ homeostasis, as well as in the regulation of the intracellular concentration of other second messengers, such as cyclic AMP and inositol trisphosphate.
FormLyophilized
FormulationLyophilized from protein solution with 2 mM EDTA.
SourcePrepared from tissue of individuals that have been shown by certified tests to be negative for HBsAg and for antibodies to HIV and HCV.
Purity≥95% by Native PAGE
Unit definitionOne unit is defined as the amount of calmodulin that will give rise to 50% of the maximal enzyme activation of a standard level of activator-deficient 3ʹ,5ʹ-cyclic nucleotide phosphodiesterase.
SolubilityReconstitute with distilled water. H₂O (1 mg/ml)
Storage -20°C
Do Not Freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C or -70°C). Aqueous stock solutions are stable for up to 2 months at -20°C or for up to 4 months at -70°C.
Toxicity Standard Handling
ReferencesO'Neil, K.T., and DeGrado, W.F. 1990. Trends Pharmacol. Sci. 15, 59.
Gopalakrishna, R., and Anderson, W.B. 1982. Biochem. Biophys. Res. Commun. 104, 830.
Sharma, R.K., and Wang, J.H. 1979. Adv. Cyclic Nucleotide Res. 10, 187.