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218740 Caspase-2 Substrate I, Fluorogenic

218740
Purchase on Sigma-Aldrich

Descripción

Replacement Information

Products

Número de referenciaEmbalaje Cant./Env.
218740-5MG Ampolla de plást. 5 mg
Description
Overview

This product has been discontinued.





A fluorogenic substrate for the detection of caspase-2 (ICH-1). Reaction can be monitored visually or quantitatively by a blue to green shift in fluorescence upon cleavage of the AFC fluorophore.
Catalogue Number218740
Brand Family Calbiochem®
SynonymsZ-VDVAD-AFC
References
ReferencesIto, A., et al. 1999. Biochim. Biophys. Acta 1452, 263.
Thornberry, N.A., and Lazebnik, Y. 1998. Science 281, 1312.
Talanian, R.V., et al. 1997. J. Biol. Chem. 272, 9677.
Product Information
FormLyophilized
Hill FormulaC₃₉H₄₅F₃N₆O₁₃
Chemical formulaC₃₉H₄₅F₃N₆O₁₃
Applications
Biological Information
Purity≥95% by HPLC
Physicochemical Information
Emission max.
Excitation max.
Peptide SequenceZ-Val-Asp-Val-Ala-Asp-AFC
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Storage and Shipping Information
Ship Code Ambient Temperature Only
Toxicity Standard Handling
Storage -20°C
Protect from Light Protect from light
Protect from Moisture Protect from moisture
Do not freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
Packaging Information
Transport Information
Supplemental Information
Specifications

Documentation

Caspase-2 Substrate I, Fluorogenic Ficha datos de seguridad (MSDS)

Título

Ficha técnica de seguridad del material (MSDS) 

Caspase-2 Substrate I, Fluorogenic Certificados de análisis

CargoNúmero de lote
218740

Referencias bibliográficas

Visión general referencias
Ito, A., et al. 1999. Biochim. Biophys. Acta 1452, 263.
Thornberry, N.A., and Lazebnik, Y. 1998. Science 281, 1312.
Talanian, R.V., et al. 1997. J. Biol. Chem. 272, 9677.

Folleto

Cargo
Caspases and other Apoptosis Related Tools Brochure
Ficha técnica

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision04-June-2008 RFH
SynonymsZ-VDVAD-AFC
DescriptionA fluorogenic substrate for detection of caspase-2 (ICH-1). Reaction can be monitored visually or quantitatively by a blue to green shift in fluorescence upon cleavage of the AFC fluorophore (excitation max: ~400 nm; emission max: ~505 nm).
FormLyophilized
Chemical formulaC₃₉H₄₅F₃N₆O₁₃
Peptide SequenceZ-Val-Asp-Val-Ala-Asp-AFC
Purity≥95% by HPLC
SolubilityDMSO (5 mg/ml)
Storage -20°C
Protect from moisture
Protect from light
Do Not Freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
Toxicity Standard Handling
ReferencesIto, A., et al. 1999. Biochim. Biophys. Acta 1452, 263.
Thornberry, N.A., and Lazebnik, Y. 1998. Science 281, 1312.
Talanian, R.V., et al. 1997. J. Biol. Chem. 272, 9677.