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233501 Coagulation Factor XIII, Human Plasma

233501
Purchase on Sigma-Aldrich

Descripción

Replacement Information

Products

Número de referenciaEmbalaje Cant./Env.
233501-100UG Ampolla de plást. 100 μg
Description
OverviewNative coagulation factor XIII from human plasma. Plasma Factor XIII is a tetramer (α2β2) composed of two identical α-subunits and two identical β-subunits. After thrombin cleavage converts the α2β2 tetramer to a modified α2′β2 tetramer, Ca2+ promotes both the dissociation of the β2 dimer and the activation of the α2′ dimer to its catalytically active form. This activated Factor XIII (Factor XIIIa) strengthens the fibrin clot by catalyzing the formation of glutamyl-lysine bonds between fibrin monomers.
Catalogue Number233501
Brand Family Calbiochem®
SynonymsFibrin-stabilizing Factor
References
Product Information
CAS number9013-56-3
Unit of DefinitionClotting activity is determined by comparison to a standard curve produced using normal pooled human plasma. One unit is defined as the activity in 1 ml of normal, pooled plasma.
FormLiquid
FormulationIn 500 µM EDTA, 50% glycerol.
Applications
Biological Information
Purity≥95% by SDS-PAGE
SourcePrepared from plasma that has been shown by certified tests to be negative for HBsAg and for antibodies to HIV and HCV.
Specific Activity≥40 units/mg protein (clotting assay)
Concentration Label Please refer to vial label for lot-specific concentration
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Storage and Shipping Information
Ship Code Blue Ice Only
Toxicity Standard Handling
Storage -20°C
Do not freeze Ok to freeze
Special InstructionsFollowing initial thaw, aliquot and freeze (-20°C).
Packaging Information
Transport Information
Supplemental Information
Specifications

Documentation

Coagulation Factor XIII, Human Plasma Ficha datos de seguridad (MSDS)

Título

Ficha técnica de seguridad del material (MSDS) 

Coagulation Factor XIII, Human Plasma Certificados de análisis

CargoNúmero de lote
233501
Ficha técnica

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision29-April-2008 RFH
SynonymsFibrin-stabilizing Factor
DescriptionNative coagulation factor XIII from human plasma. Plasma Factor XIII is a tetramer (α2β2) composed of two identical α-subunits and two identical β-subunits. After thrombin cleavage converts the α2β2 tetramer to a modified α2'β2 tetramer, Ca2+ promotes both the dissociation of β2 dimer and the activation of the α2' dimer to its catalytically active form. This activated Factor XIII (Factor XIIIa) strengthens the fibrin clot by catalyzing the formation of glutamyl-lysine bonds between fibrin monomers.
FormLiquid
FormulationIn 500 µM EDTA, 50% glycerol.
Concentration Label Please refer to vial label for lot-specific concentration
SourcePrepared from plasma that has been shown by certified tests to be negative for HBsAg and for antibodies to HIV and HCV.
CAS number9013-56-3
Purity≥95% by SDS-PAGE
Specific activity≥40 units/mg protein (clotting assay)
Unit definitionClotting activity is determined by comparison to a standard curve produced using normal pooled human plasma. One unit is defined as the activity in 1 ml of normal, pooled plasma.
Storage -20°C
Do Not Freeze Ok to freeze
Special InstructionsFollowing initial thaw, aliquot and freeze (-20°C).
Toxicity Standard Handling
Merck USA index14, 3926