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219428 Cyclin-Dependent Protein Kinase Inhibitor Set - Calbiochem

219428
Purchase on Sigma-Aldrich

Descripción

Replacement Information

Tabla espec. clave

Products

Número de referenciaEmbalaje Cant./Env.
219428-1SET Frasco de vidrio 1 set
Description
OverviewContains 5 mg of Olomoucine (Cat. No. 495620), 1 mg of Iso-Olomoucine (Cat. No. 495622), and 1 mg of Roscovitine (Cat. No. 557360). Supplied with an informational insert.
Catalogue Number219428
Brand Family Calbiochem®
References
ReferencesMeijer, L. 1996. Trends in Cell Biol. 6, 393.
Glab, N., et al. 1994. FEBS Lett. 353, 207.
Vesely, J., et al. 1994. Eur. J. Biochem. 224, 771.
Product Information
FormSolid
Applications
Biological Information
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Storage and Shipping Information
Ship Code Ambient Temperature Only
Toxicity Standard Handling
Storage -20°C
Do not freeze Ok to freeze
Packaging Information
Transport Information
Supplemental Information
Specifications

Documentation

Cyclin-Dependent Protein Kinase Inhibitor Set - Calbiochem Ficha datos de seguridad (MSDS)

Título

Ficha técnica de seguridad del material (MSDS) 

Cyclin-Dependent Protein Kinase Inhibitor Set - Calbiochem Certificados de análisis

CargoNúmero de lote
219428

Referencias bibliográficas

Visión general referencias
Meijer, L. 1996. Trends in Cell Biol. 6, 393.
Glab, N., et al. 1994. FEBS Lett. 353, 207.
Vesely, J., et al. 1994. Eur. J. Biochem. 224, 771.
Ficha técnica

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision05-June-2008 RFH
DescriptionThe eight cyclin-dependent protein kinases (Cdks) that have been identified to date play an essential role in the regulation of the cell cycle. Each Cdk is thought to be regulated by its transient association with one or more members of the cyclin family. These Cdk/cyclin complexes reportedly regulate each step of the cell cycle. For example, the G1/S transition is regulated by Cdk2/cyclin E, Cdk3/unknown cyclin, Cdk4/cyclin D1-3, Cdk6/cyclin D1, and Cdk8/cyclin C. The frequent deregulation of Cdks and their regulators in cancer has stimulated the search for potent and selective inhibitors of Cdks for both research and therapeutic use. Calbiochem® brand offers a set of two such inhibitors and a negative control compound. All three compounds are cell-permeable and act by competitively binding to the ATP binding site of the kinases.
FormSolid
Storage -20°C
Do Not Freeze Ok to freeze
Toxicity Standard Handling
ReferencesMeijer, L. 1996. Trends in Cell Biol. 6, 393.
Glab, N., et al. 1994. FEBS Lett. 353, 207.
Vesely, J., et al. 1994. Eur. J. Biochem. 224, 771.