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324788 DAPK Inhibitor - CAS 315694-89-4 - Calbiochem

324788
Purchase on Sigma-Aldrich

Descripción

Replacement Information

Tabla espec. clave

Empirical FormulaCAS #
C₁₇H₁₂N₂O₂ 315694-89-4

Products

Número de referenciaEmbalaje Cant./Env.
324788-10MG Frasco de vidrio 10 mg
Description
OverviewAn oxazalone compound that acts as a potent, ATP-competitive, and highly selective death-associated protein kinase (DAPK) inhibitor (IC50 = 69 and 225 nM against DAPK1 and DAPK3, respectively, with 10 µM ATP), while exhibiting much reduced or no activity against a panel of 48 other kinases even at concentrations as high as 10 µM.
Catalogue Number324788
Brand Family Calbiochem®
Synonyms(4Z)-4-(3-Pyridylmethylene)-2-styryl-oxazol-5-one, Death-Associated Protein Kinase Inhibitor
References
ReferencesOkamoto, M., et al. 2009. J. Med. Chem. 52, 7323.
Product Information
CAS number315694-89-4
FormYellow solid
Hill FormulaC₁₇H₁₂N₂O₂
Chemical formulaC₁₇H₁₂N₂O₂
Applications
Biological Information
Purity≥95% by HPLC
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Storage and Shipping Information
Ship Code Ambient Temperature Only
Toxicity Standard Handling
Storage +2°C to +8°C
Protect from Light Protect from light
Do not freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
Packaging Information
Packaged under inert gas Packaged under inert gas
Transport Information
Supplemental Information
Specifications

Documentation

DAPK Inhibitor - CAS 315694-89-4 - Calbiochem Ficha datos de seguridad (MSDS)

Título

Ficha técnica de seguridad del material (MSDS) 

DAPK Inhibitor - CAS 315694-89-4 - Calbiochem Certificados de análisis

CargoNúmero de lote
324788

Referencias bibliográficas

Visión general referencias
Okamoto, M., et al. 2009. J. Med. Chem. 52, 7323.
Ficha técnica

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision07-April-2011 RFH
Synonyms(4Z)-4-(3-Pyridylmethylene)-2-styryl-oxazol-5-one, Death-Associated Protein Kinase Inhibitor
DescriptionAn oxazalone compound that acts as a potent, ATP-competitive, and highly selective death-associated protein kinase (DAPK) inhibitor (IC50 = 69 and 225 nM against DAPK1 and DAPK3, respectively, with 10 µM ATP), while exhibiting much reduced or no activity against a panel of 48 other kinases even at concentrations as high as 10 µM.
FormYellow solid
Intert gas (Yes/No) Packaged under inert gas
CAS number315694-89-4
Chemical formulaC₁₇H₁₂N₂O₂
Purity≥95% by HPLC
SolubilityDMSO (25 mg/ml)
Storage +2°C to +8°C
Protect from light
Do Not Freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
Toxicity Standard Handling
ReferencesOkamoto, M., et al. 2009. J. Med. Chem. 52, 7323.