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298711 Diethyl Pyrocarbonate - CAS 1609-47-8 - Calbiochem

298711
Purchase on Sigma-Aldrich

Descripción

Replacement Information

Tabla espec. clave

Empirical FormulaCAS #
C₆H₁₀O₅ 1609-47-8

Products

Número de referenciaEmbalaje Cant./Env.
298711-100GM Frasco de vidrio 100 gm
298711-25GM Ampolla de plást. 25 gm
Description
OverviewInhibits ryanodine binding to ryanodine/Ca2+ receptor channel in skeletal muscle in a dose- and time-dependent manner and increases the Ca2+ permeability of SR vesicles. Useful for specific inactivation of nucleases during isolation of undegraded polynucleotides. Also inhibits platelet-activating factor acetyl hydrolase. Has been used as a probe for the topography of 5.8S rRNA in yeast ribosomes.
Catalogue Number298711
Brand Family Calbiochem®
SynonymsDiethyl Oxydiformate, DEPC
References
ReferencesShoshan-Barmatz, V., and Weil, S. 1994. Biochem. J. 299, 177.
Blumbers, D.O. 1987. Methods Enzymol. 152, 20.
Product Information
CAS number1609-47-8
ATP CompetitiveN
FormClear colorless liquid
Hill FormulaC₆H₁₀O₅
Chemical formulaC₆H₁₀O₅
ReversibleN
Applications
Biological Information
Primary TargetInhibits ryanodine binding to ryanodine/Ca2+ receptor channel in skeletal muscle
Purity≥96% by titration
Physicochemical Information
Cell permeableN
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
RTECSLQ9350000
Safety Information
R PhraseR: 22-36/37/38

Harmful if swallowed.
Irritating to eyes, respiratory system and skin.
S PhraseS: 26-36

In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
Wear suitable protective clothing.
Product Usage Statements
Storage and Shipping Information
Ship Code Ambient Temperature Only
Toxicity Harmful
Storage +2°C to +8°C
Protect from Light Protect from light
Do not freeze Ok to freeze
Packaging Information
Transport Information
Supplemental Information
Specifications

Documentation

Diethyl Pyrocarbonate - CAS 1609-47-8 - Calbiochem Ficha datos de seguridad (MSDS)

Título

Ficha técnica de seguridad del material (MSDS) 

Diethyl Pyrocarbonate - CAS 1609-47-8 - Calbiochem Certificados de análisis

CargoNúmero de lote
298711

Referencias bibliográficas

Visión general referencias
Shoshan-Barmatz, V., and Weil, S. 1994. Biochem. J. 299, 177.
Blumbers, D.O. 1987. Methods Enzymol. 152, 20.
Ficha técnica

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision08-October-2019 JSW
SynonymsDiethyl Oxydiformate, DEPC
DescriptionInhibits ryanodine binding to ryanodine/Ca2+ receptor channel in skeletal muscle. Useful for specific inactivation of nucleases during isolation of undegraded polynucleotides. Also inhibits platelet-activating factor acetyl hydrolase. Has been used as a probe for the topography of 5.8S rRNA in yeast ribosomes.
FormClear colorless liquid
CAS number1609-47-8
RTECSLQ9350000
Chemical formulaC₆H₁₀O₅
Purity≥96% by titration
SolubilityChloroform or Ethanol
Storage +2°C to +8°C
Protect from light
Do Not Freeze Ok to freeze
Toxicity Harmful
Merck USA index14, 7998
ReferencesShoshan-Barmatz, V., and Weil, S. 1994. Biochem. J. 299, 177.
Blumbers, D.O. 1987. Methods Enzymol. 152, 20.