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344101 FSB - CAS 891180-93-1 - Calbiochem

344101
Purchase on Sigma-Aldrich

Descripción

Replacement Information

Tabla espec. clave

Empirical FormulaCAS #
C₂₄H₁₇FO₆ 760988-03-2

Products

Número de referenciaEmbalaje Cant./Env.
344101-5MG Ampolla de plást. 5 mg
Description
OverviewA fluorine analog of the amyloidophilic fluorescent probe BSB (Cat. No. 286895) that crosses the blood-brain barrier and displays low toxicity (LD50 > 80 mg/kg). Suitiable for non-invasive amyloid visualization in living transgenic Tg2576 mice by using 19F and 1H-MRI (Magnetic Resonance Imaging). Also useful for staining plaques and neurofibrillary tangles in brain tissue sections of Alzheimer's diseased patients with improved sensitivity, and reduced background.
Catalogue Number344101
Brand Family Calbiochem®
Synonyms(E,E)-1-Fluoro-2,5-bis(3-hydroxycarbonyl-4-hydroxy)styrylbenzene
References
ReferencesHiguchi, M., et al. 2005. Nat. Neurosci. 8, 527.
Sato, K., et al. 2004. Eur. J. Med. Chem. 39, 573.
Product Information
CAS number760988-03-2
ATP CompetitiveN
FormYellow solid
Hill FormulaC₂₄H₁₇FO₆
Chemical formulaC₂₄H₁₇FO₆
ReversibleN
Structure formula ImageStructure formula Image
Applications
Biological Information
Primary TargetAmyloidophilic fluorescent probe
Purity≥95% by HPLC
Physicochemical Information
Cell permeableN
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Storage and Shipping Information
Ship Code Ambient Temperature Only
Toxicity Standard Handling
Storage -20°C
Protect from Light Protect from light
Do not freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
Packaging Information
Packaged under inert gas Packaged under inert gas
Transport Information
Supplemental Information
Specifications

Documentation

FSB - CAS 891180-93-1 - Calbiochem Ficha datos de seguridad (MSDS)

Título

Ficha técnica de seguridad del material (MSDS) 

FSB - CAS 891180-93-1 - Calbiochem Certificados de análisis

CargoNúmero de lote
344101

Referencias bibliográficas

Visión general referencias
Higuchi, M., et al. 2005. Nat. Neurosci. 8, 527.
Sato, K., et al. 2004. Eur. J. Med. Chem. 39, 573.
Ficha técnica

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision26-June-2008 RFH
Synonyms(E,E)-1-Fluoro-2,5-bis(3-hydroxycarbonyl-4-hydroxy)styrylbenzene
DescriptionA fluorine analog of the amyloidophilic fluorescent probe BSB (Cat. No. 286895) that crosses the blood-brain barrier and displays low toxicity (LD50 >80 mg/kg). Suitable for non-invasive amyloid visualization in living transgenic Tg2576 mice by using 19F and 1H-MRI (Magnetic Resonance Imaging). Also useful for staining plaques and neurofibrillary tangles in brain tissue sections of Alzheimer's diseased patients with improved sensitivity, and reduced background.
FormYellow solid
Intert gas (Yes/No) Packaged under inert gas
CAS number760988-03-2
Chemical formulaC₂₄H₁₇FO₆
Structure formulaStructure formula
Purity≥95% by HPLC
SolubilityDMSO (200 mg/ml)
Storage -20°C
Protect from light
Do Not Freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
Toxicity Standard Handling
ReferencesHiguchi, M., et al. 2005. Nat. Neurosci. 8, 527.
Sato, K., et al. 2004. Eur. J. Med. Chem. 39, 573.