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368620 Group III Caspase Inhibitor I - Calbiochem

368620
Purchase on Sigma-Aldrich

Descripción

Replacement Information

Tabla espec. clave

Empirical Formula
C₂₈H₃₉FN₄O₁₀

Products

Número de referenciaEmbalaje Cant./Env.
368620-1MG Ampolla de plást. 1 mg
Description
OverviewA potent, cell-permeable, and irreversible inhibitor of Group III caspases (caspase-6, -8, -9, and -10), although more effective towards caspases-6 and -8. Also inhibits caspase-1 and caspase-3. When using with purified native or recombinant enzyme, pretreatment with an esterase is required.
Catalogue Number368620
Brand Family Calbiochem®
SynonymsZ-AE(OMe)VD(OMe)-FMK
References
ReferencesGarcia-Calvo, M., et al. 1998. J. Biol. Chem. 273, 32608.
Product Information
ATP CompetitiveN
FormWhite solid
Hill FormulaC₂₈H₃₉FN₄O₁₀
Chemical formulaC₂₈H₃₉FN₄O₁₀
ReversibleN
Applications
Biological Information
Primary Targetcaspase-1, caspase-3, caspase-6, caspase-8, caspase-9, caspase-10
PuritySingle spot by TLC
Physicochemical Information
Cell permeableY
Peptide SequenceZ-Ala-Glu(OMe)-Val-Asp(OMe)-CH₂F*
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Storage and Shipping Information
Ship Code Ambient Temperature Only
Toxicity Standard Handling
Storage -20°C
Protect from Moisture Protect from moisture
Do not freeze Ok to freeze
Special InstructionsFollowing reconstituion, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
Packaging Information
Transport Information
Supplemental Information
Specifications

Documentation

Group III Caspase Inhibitor I - Calbiochem Ficha datos de seguridad (MSDS)

Título

Ficha técnica de seguridad del material (MSDS) 

Group III Caspase Inhibitor I - Calbiochem Certificados de análisis

CargoNúmero de lote
368620

Referencias bibliográficas

Visión general referencias
Garcia-Calvo, M., et al. 1998. J. Biol. Chem. 273, 32608.

Folleto

Cargo
Caspases and other Apoptosis Related Tools Brochure
Ficha técnica

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision07-July-2008 RFH
SynonymsZ-AE(OMe)VD(OMe)-FMK
DescriptionA potent, cell-permeable, and irreversible inhibitor of Group III caspases (caspases-6, -8, -9, and -10), although more effective towards caspases -6 and -8. Also inhibits caspase-1 and caspase-3. When using with purified native or recombinant enzyme, pretreatment with an esterase is required.
FormWhite solid
Chemical formulaC₂₈H₃₉FN₄O₁₀
Peptide SequenceZ-Ala-Glu(OMe)-Val-Asp(OMe)-CH₂F*
PuritySingle spot by TLC
SolubilityDMSO (20 mM)
Storage -20°C
Protect from moisture
Do Not Freeze Ok to freeze
Special InstructionsFollowing reconstituion, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
Toxicity Standard Handling
ReferencesGarcia-Calvo, M., et al. 1998. J. Biol. Chem. 273, 32608.