113000 Acridine Orange - CAS 65-61-2 - Calbiochem

113000
Price could not be retrieved
Minimum Quantity needs to be mulitiple of
Upon Order Completion More Information
You Saved ()
 
Request Pricing
Limited AvailabilityLimited Availability
In Stock 
Discontinued
Limited Quantities Available
Availability to be confirmed
    Remaining : Will advise
      Remaining : Will advise
      Will advise
      Contact Customer Service
      Contact Customer Service
      View Pricing & Availability
      Click To Print This Page

      Overview

      Replacement Information

      Key Spec Table

      Empirical FormulaCAS #
      C₁₇H₂₀ClN₃65-61-2

      Pricing & Availability

      Catalogue NumberAvailability Packaging Qty/Pack Price Quantity
      113000-1GM
      Retrieving availability...
      Limited AvailabilityLimited Availability
      In Stock 
      Discontinued
      Limited Quantities Available
      Availability to be confirmed
        Remaining : Will advise
          Remaining : Will advise
          Will advise
          Contact Customer Service
          Contact Customer Service

          Glass bottle 1 gm
          Retrieving price...
          Price could not be retrieved
          Minimum Quantity needs to be mulitiple of
          Upon Order Completion More Information
          You Saved ()
           
          Request Pricing
          Description
          OverviewA cell-permeable, cationic fluorescent dye that interacts with DNA and RNA by intercalation or electrostatic attractions. When bound to DNA, it is spectrally very similar to fluorescein, with an excitation maximum at 502 nm and an emission maximum at 525 nm. Upon association with RNA, the excitation maximum shifts to 460 nm and the emission maximum shifts to 650 nm (red). Often used to measure single- and double-stranded DNA and RNA in the diagnosis, classification, and prognosis of many neoplasms. A very versatile fluorescent stain used in histochemistry and cytochemistry that can be used to provide information about the in situ content, molecular structure, and conformation of many nucleic acid-containing cell constituents.
          Catalogue Number113000
          Brand Family Calbiochem®
          SynonymsAO, 3,6-bis(Dimethylamino)acridine, HCl
          References
          ReferencesGonzalez, K., et al. 1995. Curr. Eye Res. 14, 269.
          Muro-Cacho, C.A., et al. 1995. J. Immunol. 154, 5555.
          Olivier, R. 1995. Methods Enzymol. 251, 270.
          Busch, G.L., et al. 1994. Proc. Natl. Acad. Sci. USA 91, 9165.
          Darzynkiewicz, Z. 1994. Methods Cell. Biol. 41, 401.
          Delic, J., et al. 1991. Exp. Cell Res. 194, 147.
          El-Naggar, A.K., et al. 1991. Cytometry 12, 330.
          Lopez, F., et al. 1991. Cytometry 12, 42.
          Gurrieri, S., et al. 1990. Biochemistry 29, 3396.
          Hermansen, D.K., et al. 1989. Cytometry 10, 739.
          Product Information
          CAS number65-61-2
          ATP CompetitiveN
          FormBurnt-orange solid
          Hill FormulaC₁₇H₂₀ClN₃
          Chemical formulaC₁₇H₂₀ClN₃
          Hygroscopic Hygroscopic
          ReversibleN
          Structure formula ImageStructure formula Image
          Applications
          Biological Information
          Primary TargetInteracts with DNA and RNA
          Purity≥98% by HPLC
          Physicochemical Information
          Cell permeableY
          Dimensions
          Materials Information
          Toxicological Information
          Safety Information according to GHS
          RTECSAR7601000
          Safety Information
          R PhraseR: 20/21/22-40

          Harmful by inhalation, in contact with skin and if swallowed.
          Limited evidence of a carcinogenic effect.
          S PhraseS: 36

          Wear suitable protective clothing.
          Product Usage Statements
          Storage and Shipping Information
          Ship Code Ambient Temperature Only
          Toxicity Harmful & Carcinogenic / Teratogenic
          Storage +15°C to +30°C
          Protect from Light Protect from light
          Hygroscopic Hygroscopic
          Do not freeze Ok to freeze
          Special InstructionsFollowing reconstitution, store in the refrigerator (4°C). Aqueous stock solutions are stable for up to 1 month at 4°C.
          Packaging Information
          Transport Information
          Supplemental Information
          Specifications

          Documentation

          SDS

          Title

          Safety Data Sheet (SDS) 

          Certificates of Analysis

          TitleLot Number
          113000

          References

          Reference overview
          Gonzalez, K., et al. 1995. Curr. Eye Res. 14, 269.
          Muro-Cacho, C.A., et al. 1995. J. Immunol. 154, 5555.
          Olivier, R. 1995. Methods Enzymol. 251, 270.
          Busch, G.L., et al. 1994. Proc. Natl. Acad. Sci. USA 91, 9165.
          Darzynkiewicz, Z. 1994. Methods Cell. Biol. 41, 401.
          Delic, J., et al. 1991. Exp. Cell Res. 194, 147.
          El-Naggar, A.K., et al. 1991. Cytometry 12, 330.
          Lopez, F., et al. 1991. Cytometry 12, 42.
          Gurrieri, S., et al. 1990. Biochemistry 29, 3396.
          Hermansen, D.K., et al. 1989. Cytometry 10, 739.

          Brochure

          Title
          Caspases and other Apoptosis Related Tools Brochure
          Dyes and Stains Technical Bulletin
          Data Sheet

          Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

          Revision07-April-2008 RFH
          SynonymsAO, 3,6-bis(Dimethylamino)acridine, HCl
          DescriptionA cell-permeable fluorescent dye that interacts with DNA and RNA by intercalation or electrostatic attractions. When bound to DNA, this cationic dye is spectrally very similar to fluorescein, with an excitation maximum at 502 nm and an emission maximum at 525 nm. Upon association with RNA, the excitation maximum shifts to 460 nm and the emission maximum shifts to 650 nm (red). Often used to measure single- and double-stranded DNA and RNA in the diagnosis, classification, and prognostication of many neoplasms. A very versatile fluorescent stain used in histochemistry and cytochemistry providing information about the in situ content, molecular structure, conformation, and environment of many nucleic acid-containing cell constituents.
          FormBurnt-orange solid
          CAS number65-61-2
          RTECSAR7601000
          Chemical formulaC₁₇H₂₀ClN₃
          Structure formulaStructure formula
          Purity≥98% by HPLC
          SolubilityDMF, Ethanol, or H₂O (1 mg/ml)
          Storage +15°C to +30°C
          Hygroscopic
          Protect from light
          Do Not Freeze Ok to freeze
          Special InstructionsFollowing reconstitution, store in the refrigerator (4°C). Aqueous stock solutions are stable for up to 1 month at 4°C.
          Toxicity Harmful & Carcinogenic / Teratogenic
          ReferencesGonzalez, K., et al. 1995. Curr. Eye Res. 14, 269.
          Muro-Cacho, C.A., et al. 1995. J. Immunol. 154, 5555.
          Olivier, R. 1995. Methods Enzymol. 251, 270.
          Busch, G.L., et al. 1994. Proc. Natl. Acad. Sci. USA 91, 9165.
          Darzynkiewicz, Z. 1994. Methods Cell. Biol. 41, 401.
          Delic, J., et al. 1991. Exp. Cell Res. 194, 147.
          El-Naggar, A.K., et al. 1991. Cytometry 12, 330.
          Lopez, F., et al. 1991. Cytometry 12, 42.
          Gurrieri, S., et al. 1990. Biochemistry 29, 3396.
          Hermansen, D.K., et al. 1989. Cytometry 10, 739.