116802 Adenosine 3ʹ,5ʹ-cyclic Monophosphate, N⁶-Benzoyl-, Sodium Salt - CAS 30275-80-0 - Calbiochem

116802
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      Overview

      Replacement Information

      Key Spec Table

      Empirical FormulaCAS #
      C₁₇H₁₅N₅O₇P · Na30275-80-0

      Pricing & Availability

      Catalogue NumberAvailability Packaging Qty/Pack Price Quantity
      116802-10UMOL
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          Glass bottle 10 umol
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          Description
          OverviewA potent cell-permeable activator of cAMP-dependent protein kinase (PKA). Activates both type 1 and type 2 PKA and binds to the cAMP binding site 2 on the regulatory subunit of PKA. It is only slowly metabolized by cyclic nucleotide-dependent phosphodiesterases. Due to its considerably increased lipophilicity, it has sufficient membrane permeability for many biological systems.
          Note: 10 µmol = 4.55 mg.
          Catalogue Number116802
          Brand Family Calbiochem®
          Synonyms6-Bnz-cAMP, Na
          References
          ReferencesDøskeland, S.O., et al. 1993. Biochim. Biophys. Acta 1178, 249.
          Laurent-Cadoret, V., et al. 1993. Acta Endocrinol. 128, 555.
          Zorn, M., et al. 1993. Eur. J. Cell Biol. 60, 351.
          Product Information
          CAS number30275-80-0
          ATP CompetitiveN
          FormLyophilized
          Hill FormulaC₁₇H₁₅N₅O₇P · Na
          Chemical formulaC₁₇H₁₅N₅O₇P · Na
          Hygroscopic Hygroscopic
          ReversibleN
          Structure formula ImageStructure formula Image
          Applications
          ApplicationAdenosine 3ʹ,5ʹ-cyclic Monophosphate, N⁶-Benzoyl-, Sodium Salt, CAS 30275-80-0, is a cell-permeable, potent activator of PKA type 1 & 2. Binds to the cAMP binding site 2 on the regulatory unit of PKA.
          Biological Information
          Primary TargetPKA
          Purity≥98% by HPLC
          Physicochemical Information
          Cell permeableY
          Dimensions
          Materials Information
          Toxicological Information
          Safety Information according to GHS
          Safety Information
          Product Usage Statements
          Storage and Shipping Information
          Ship Code Ambient Temperature Only
          Toxicity Standard Handling
          Storage -20°C
          Hygroscopic Hygroscopic
          Do not freeze Ok to freeze
          Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
          Packaging Information
          Transport Information
          Supplemental Information
          Specifications

          Documentation

          SDS

          Title

          Safety Data Sheet (SDS) 

          Certificates of Analysis

          TitleLot Number
          116802

          References

          Reference overview
          Døskeland, S.O., et al. 1993. Biochim. Biophys. Acta 1178, 249.
          Laurent-Cadoret, V., et al. 1993. Acta Endocrinol. 128, 555.
          Zorn, M., et al. 1993. Eur. J. Cell Biol. 60, 351.
          Data Sheet

          Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

          Revision06-September-2007 RFH
          Synonyms6-Bnz-cAMP, Na
          DescriptionA potent, non-degradable, cell-permeable analog of cAMP that binds to the cAMP binding site 2 on the protein kinase A (PKA) regulatory subunit and activates both type I and II PKA. λmax = 279 nm (H2O, pH 7.0); εmax = 17,000 M-1cm-1.
          FormLyophilized
          CAS number30275-80-0
          Chemical formulaC₁₇H₁₅N₅O₇P · Na
          Structure formulaStructure formula
          Purity≥98% by HPLC
          SolubilityH₂O (10 mg/ml)
          Storage -20°C
          Hygroscopic
          Do Not Freeze Ok to freeze
          Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
          Toxicity Standard Handling
          ReferencesDøskeland, S.O., et al. 1993. Biochim. Biophys. Acta 1178, 249.
          Laurent-Cadoret, V., et al. 1993. Acta Endocrinol. 128, 555.
          Zorn, M., et al. 1993. Eur. J. Cell Biol. 60, 351.