05-23-0300 Atrial Natriuretic Factor 1-28, Human - CAS 91917-63-4 - Calbiochem

05-23-0300
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      Overview

      Replacement Information

      Key Spec Table

      Empirical FormulaCAS #
      C₁₂₇H₂₀₃N₄₅O₃₉S₃91917-63-4

      Pricing & Availability

      Catalogue NumberAvailability Packaging Qty/Pack Price Quantity
      05-23-0300-0.5MG
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          Plastic ampoule .5 mg
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          05-23-0300-1MG
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              Plastic ampoule 1 mg
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              Description
              OverviewIncreases the rate of renal excretion. Higher levels are reported in congestive heart failure. Inhibits MAP kinase through the natriuretic peptide clearance receptor.
              Catalogue Number05-23-0300
              Brand Family Calbiochem®
              SynonymshANF, ANP, SLRRSSCFGGRMDRIGAQSGLGCNSFRY
              References
              ReferencesPrins, B.A., et al. 1996. J. Biol. Chem. 271, 14156.
              Yechieli, H., et al. 1993. Am. J. Physiol. 265, F119.
              Product Information
              CAS number91917-63-4
              ATP CompetitiveN
              FormWhite to off-white lyophilized solid
              FormulationSupplied as a trifluoroacetate salt.
              Hill FormulaC₁₂₇H₂₀₃N₄₅O₃₉S₃
              Chemical formulaC₁₂₇H₂₀₃N₄₅O₃₉S₃
              Hygroscopic Hygroscopic
              ReversibleN
              Sold on the basis of peptide contentY
              Applications
              Biological Information
              Primary TargetIncreases the rate of renal excretion
              Purity≥97% by HPLC
              Physicochemical Information
              Cell permeableN
              Peptide ContentY
              Peptide SequenceH-Ser-Leu-Arg-Arg-Ser-Ser-Cys⁷-Phe-Gly-Gly-Arg-Met-Asp-Arg-Ile-Gly-Ala-Gln-Ser-Gly-Leu-Gly-Cys²³-Asn-Ser-Phe-Arg-Tyr-OH (disulfide bond: 7 → 23)
              Dimensions
              Materials Information
              Toxicological Information
              Safety Information according to GHS
              Safety Information
              Product Usage Statements
              Storage and Shipping Information
              Ship Code Ambient Temperature Only
              Toxicity Standard Handling
              Storage -20°C
              Hygroscopic Hygroscopic
              Do not freeze Ok to freeze
              Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 1 month at -20°C.
              Packaging Information
              Transport Information
              Supplemental Information
              Specifications

              Documentation

              SDS

              Title

              Safety Data Sheet (SDS) 

              Certificates of Analysis

              TitleLot Number
              05-23-0300

              References

              Reference overview
              Prins, B.A., et al. 1996. J. Biol. Chem. 271, 14156.
              Yechieli, H., et al. 1993. Am. J. Physiol. 265, F119.
              Data Sheet

              Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

              Revision18-September-2008 RFH
              SynonymshANF, ANP, SLRRSSCFGGRMDRIGAQSGLGCNSFRY
              DescriptionIncreases the rate of renal excretion. Higher levels are reported in congestive heart failure. Inhibits MAP kinase through the clearance receptor.
              FormWhite to off-white lyophilized solid
              FormulationSupplied as a trifluoroacetate salt.
              CAS number91917-63-4
              Chemical formulaC₁₂₇H₂₀₃N₄₅O₃₉S₃
              Peptide SequenceH-Ser-Leu-Arg-Arg-Ser-Ser-Cys⁷-Phe-Gly-Gly-Arg-Met-Asp-Arg-Ile-Gly-Ala-Gln-Ser-Gly-Leu-Gly-Cys²³-Asn-Ser-Phe-Arg-Tyr-OH (disulfide bond: 7 → 23)
              Purity≥97% by HPLC
              Solubility5% acetic acid (1 mg/ml)
              Storage -20°C
              Hygroscopic
              Do Not Freeze Ok to freeze
              Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 1 month at -20°C.
              Toxicity Standard Handling
              Merck USA index14 1360
              ReferencesPrins, B.A., et al. 1996. J. Biol. Chem. 271, 14156.
              Yechieli, H., et al. 1993. Am. J. Physiol. 265, F119.