114700 | Activin A, Human, Recombinant, CHO Cells

114700
Le prix n'a pas pu être récupéré
La quantité minimale doit être un multiple de
À la validation de la commande Plus d'informations
Vous avez sauvegardé ()
 
Demander le prix
Disponibilité limitéeDisponibilité limitée
En stock 
Interrompu(e)
Disponible en quantités limitées
Disponibilité à confirmer
    Pour le restant : Nous vous tiendrons informé
      Pour le restant : Nous vous tiendrons informé
      Nous vous tiendrons informé
      Contacter le Service Clients
      Voir les Prix & la Disponibilité
      Click To Print This Page

      Aperçu

      Replacement Information

      Tableau de caractéristiques principal

      Purity
      ≥95% by SDS-PAGE

      Prix & Disponibilité

      RéférenceDisponibilité Conditionnement Qté Prix Quantité
      114700-10UG
      Récupération des données relatives à la disponibilité...
      Disponibilité limitéeDisponibilité limitée
      En stock 
      Interrompu(e)
      Disponible en quantités limitées
      Disponibilité à confirmer
        Pour le restant : Nous vous tiendrons informé
          Pour le restant : Nous vous tiendrons informé
          Nous vous tiendrons informé
          Contacter le Service Clients

          Ampoule plast. 10 μg
          Prix en cours de récupération
          Le prix n'a pas pu être récupéré
          La quantité minimale doit être un multiple de
          À la validation de la commande Plus d'informations
          Vous avez sauvegardé ()
           
          Demander le prix
          Description
          OverviewRecombinant, human activin A (disulfide-linked homodimer of two 116-amino acid residue βA subunits) expressed in CHO cells. Mature βA-monomer lacks a potential N-linked glycosylation site and has a calculated molecular weight of 13 kDa. A member of the TGF-β superfamily that is involved in the negative regulation of B lineage lymphocytes. Shown to play an important role in the regulation of hormonogenesis, cellular homeostasis, and differentiation programs. Reported to inhibit endogenous production of IL-6.
          Catalogue Number114700
          Brand Family Calbiochem®
          References
          ReferencesZipori, D., et al. 2001. J. Leukoc. Biol. 69, 867.
          Hedger, M.P., et al. 2000. Cytokine 12, 595.
          Woodruff, T.K. 1998. Biochem. Pharmacol. 55, 953.
          Ying, S.Y., et al. 1997. Proc. Soc. Exp. Biol. Med. 214, 114.
          Schwall, R.H., and Lei, C. 1991. Methods Enzymol. 198, 340.
          Mason, A., et al. 1986. Biochem. Biophys. Res. Commun. 135, 957.
          Product Information
          FormLyophilized
          FormulationLyophilized from sterile filtered 35% acetonitrile, 0.1% TFA, 50 µg BSA/µg Activin A.
          Applications
          Biological Information
          Biological activityED₅₀ = 0.5-2.0 ng/ml as measured by its ability to induce hemoglobin expression in K562 cells
          Purity≥95% by SDS-PAGE
          Physicochemical Information
          ContaminantsEndotoxin: ≤100 pg/µg Activin A
          Dimensions
          Materials Information
          Toxicological Information
          Safety Information according to GHS
          Safety Information
          Product Usage Statements
          Storage and Shipping Information
          Ship Code Ambient Temperature Only
          Toxicity Standard Handling
          Storage ≤ -70°C
          Do not freeze Ok to freeze
          Special InstructionsFollowing reconstitution, aliquot and freeze (-70°C). Stock solutions are stable for up to 3 months at -70°C. Avoid freeze/thaw cycles of solutions.
          Packaging Information
          Transport Information
          Supplemental Information
          Specifications

          Documentation

          FDS

          Titre

          Fiche de données de sécurité des matériaux (FDS) 

          Certificats d'analyse

          TitreNuméro de lot
          114700

          Références bibliographiques

          Aperçu de la référence bibliographique
          Zipori, D., et al. 2001. J. Leukoc. Biol. 69, 867.
          Hedger, M.P., et al. 2000. Cytokine 12, 595.
          Woodruff, T.K. 1998. Biochem. Pharmacol. 55, 953.
          Ying, S.Y., et al. 1997. Proc. Soc. Exp. Biol. Med. 214, 114.
          Schwall, R.H., and Lei, C. 1991. Methods Enzymol. 198, 340.
          Mason, A., et al. 1986. Biochem. Biophys. Res. Commun. 135, 957.

          Brochure

          Titre
          Growth Factors and Cytokines Technical Bulletin
          Fiche technique

          Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

          Revision07-April-2008 RFH
          DescriptionRecombinant, human activin A (disulfide-linked homodimer of two 116-amino acid residue βA subunits) expressed in CHO cells. Mature βA-monomer lacks a potential N-linked glycosylation site and has a calculated molecular mass of 13 kDa. Activins are members of the TGF-β superfamily and have been shown to play an important role in the regulation of homonogenesis, cellular homeostasis, and differentiation programs.
          FormLyophilized
          FormulationLyophilized from sterile filtered 35% acetonitrile, 0.1% TFA, 50 µg BSA/µg Activin A.
          Purity≥95% by SDS-PAGE
          ContaminantsEndotoxin: ≤100 pg/µg Activin A
          Biological activityED₅₀ = 0.5-2.0 ng/ml as measured by its ability to induce hemoglobin expression in K562 cells
          SolubilityReconstitute to a concentration ≥10 µg/ml with sterile PBS containing ≥0.1% HSA or BSA.
          Storage ≤ -70°C
          Do Not Freeze Ok to freeze
          Special InstructionsFollowing reconstitution, aliquot and freeze (-70°C). Stock solutions are stable for up to 3 months at -70°C. Avoid freeze/thaw cycles of solutions.
          Toxicity Standard Handling
          ReferencesZipori, D., et al. 2001. J. Leukoc. Biol. 69, 867.
          Hedger, M.P., et al. 2000. Cytokine 12, 595.
          Woodruff, T.K. 1998. Biochem. Pharmacol. 55, 953.
          Ying, S.Y., et al. 1997. Proc. Soc. Exp. Biol. Med. 214, 114.
          Schwall, R.H., and Lei, C. 1991. Methods Enzymol. 198, 340.
          Mason, A., et al. 1986. Biochem. Biophys. Res. Commun. 135, 957.