178486 Apoptosis Inducer Set I - Calbiochem

178486
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      RéférenceDisponibilité Conditionnement Qté Prix Quantité
      178486-1SET
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      Disponibilité limitéeDisponibilité limitée
      En stock 
      Interrompu(e)
      Disponible en quantités limitées
      Disponibilité à confirmer
        Pour le restant : Nous vous tiendrons informé
          Pour le restant : Nous vous tiendrons informé
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          Boîte carton 1 set
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          Description
          OverviewThis set contains five ready-to-use chemical reagents that induce apoptosis through different mechanisms. The set contains DMSO solutions of Actinomycin D, Streptomyces sp. (10 mM; Cat. No. 114666), Camptothecin, Camptotheca acuminata (2 mM; Cat. No. 208925), Cycloheximide (100 mM; Cat. No. 239764), Dexamethasone (10 mM; Cat. No. 265005), and Etoposide (100 mM; Cat. No. 341205). Recommended dilution for use: 1:1000. Supplied with a data sheet.
          Catalogue Number178486
          Brand Family Calbiochem®
          Application Data
          References
          ReferencesSuzuki, A., and Keto, M. 1996. Exp. Cell. Res. 227, 154.
          Martin, S.J., et al. 1995. J. Exp. Med. 182, 1545.
          Nicholson, D.W., et al. 1995. Nature 376, 37.
          Fearnhead, H.O., et al. 1994. Biochem. Pharmacol. 48, 1073.
          Onishi, Y., et al. 1993. Biochem. Biophys. Acta 1175, 147.
          Product Information
          FormLiquid
          FormulationAll components are supplied in DMSO.
          Applications
          Biological Information
          Physicochemical Information
          Dimensions
          Materials Information
          Toxicological Information
          Safety Information according to GHS
          Safety Information
          R PhraseR: 26/27/28-36/37/38-43-45-46-40-61-62-63

          Very toxic by inhalation, in contact with skin and if swallowed.
          Irritating to eyes, respiratory system and skin.
          May cause sensitization by skin contact.
          May cause cancer.
          May cause heritable genetic damage.
          Limited evidence of a carcinogenic effect.
          May cause harm to the unborn child.
          Possible risk of impaired fertility.
          Possible risk of harm to the unborn child.
          S PhraseS: 26-36/37/39-45-53-3/7/9-23

          In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
          Wear suitable protective clothing, gloves and eye/face protection.
          In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible).
          Avoid exposure - obtain special instructions before use.
          Keep container tightly closed, in a cool well ventilated place.
          Do not breathe fumes.
          Product Usage Statements
          Storage and Shipping Information
          Ship Code Ambient Temperature Only
          Toxicity Multiple Toxicity Values, refer to MSDS
          Hazardous Materials Attention: Due to the nature of the Hazardous Materials in this shipment, additional shipping charges may be applied to your order. Certain sizes may be exempt from the additional hazardous materials shipping charges. Please contact your local sales office for more information regarding these charges.
          Storage -20°C
          Protect from Light Protect from light
          Do not freeze Ok to freeze
          Special InstructionsFollowing initial thaw, aliquot and freeze (-20°C).
          Packaging Information
          Transport Information
          Supplemental Information
          Specifications

          Documentation

          FDS

          Titre

          Fiche de données de sécurité des matériaux (FDS) 

          Certificats d'analyse

          TitreNuméro de lot
          178486

          Références bibliographiques

          Aperçu de la référence bibliographique
          Suzuki, A., and Keto, M. 1996. Exp. Cell. Res. 227, 154.
          Martin, S.J., et al. 1995. J. Exp. Med. 182, 1545.
          Nicholson, D.W., et al. 1995. Nature 376, 37.
          Fearnhead, H.O., et al. 1994. Biochem. Pharmacol. 48, 1073.
          Onishi, Y., et al. 1993. Biochem. Biophys. Acta 1175, 147.

          Brochure

          Titre
          Caspases and other Apoptosis Related Tools Brochure
          Fiche technique

          Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

          Revision15-April-2008 RFH
          Application Data
          DescriptionThe set contains 5 ready-to-use chemical reagents that induce apoptosis through different mechanisms. Actinomycin D, an anti-neoplastic antibiotic, inhibits RNA synthesis. Camptothecin and etoposide are inhibitors of nuclear topoisomerase. Cycloheximide, an active antibiotic against many yeast and fungi, inhibits protein synthesis. Dexamethasone, an active and highly stable glucocorticoid, probably induces apoptosis by binding and activating the intracellular glucocorticoid receptor. Supplied with a data sheet.
          FormLiquid
          FormulationAll components are supplied in DMSO.
          Recommended reaction conditionsA 1:1000 is recommended for inducing apoptosis in cell culture with these apoptosis-inducing reagents. The optimal dosie may vary for different cell types and culture conditions. Please consult published literature to determine the optimal concentration and incubation time for specific cell types.
          Storage -20°C
          Protect from light
          Do Not Freeze Ok to freeze
          Special InstructionsFollowing initial thaw, aliquot and freeze (-20°C).
          Toxicity Multiple Toxicity Values, refer to MSDS
          ReferencesSuzuki, A., and Keto, M. 1996. Exp. Cell. Res. 227, 154.
          Martin, S.J., et al. 1995. J. Exp. Med. 182, 1545.
          Nicholson, D.W., et al. 1995. Nature 376, 37.
          Fearnhead, H.O., et al. 1994. Biochem. Pharmacol. 48, 1073.
          Onishi, Y., et al. 1993. Biochem. Biophys. Acta 1175, 147.