567737 | S1P4 Receptor Antagonist, CYM50358 - Calbiochem

567737
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      Overview

      Replacement Information

      Tableau de caractéristiques principal

      Empirical Formula
      C₂₀H₁₈Cl₂N₂O₂

      Prix & Disponibilité

      RéférenceDisponibilité Conditionnement Qté Prix Quantité
      567737-5MG
      Récupération des données relatives à la disponibilité...
      Disponibilité limitée Disponibilité limitée
      Interrompu(e)
      Disponible en quantités limitées
      Disponibilité à confirmer
        Remaining : Will advise
          Nous vous tiendrons informé

          5 mg
          Prix en cours de récupération
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          Description
          Overview An arylcarboxamide that acts as a potent and selective sphingosine-1-phosphate receptor 4 (S1P4) antagonist (IC50 = 25 nM), among a panel of five S1P receptors. It is shown to inhibit other S1P isoforms only at much higher concentrations (IC50 = 6.4 µM, 3.9 µM, 5.5 µM, and 25 µM for S1P1, S1P2, S1P5, and S1P3 (95% inhibition), respectively).
          Catalogue Number 567737
          Brand Family Calbiochem®
          Synonyms CYM50358
          References
          References Guerrero, M., et al. 2011. Bioorg. Med. Chem. Lett. 21, 3632.
          Product Information
          Form White solid
          Hill Formula C₂₀H₁₈Cl₂N₂O₂
          Chemical formula C₂₀H₁₈Cl₂N₂O₂
          Molar Mass 389.28
          Structure formula Image
          Applications
          Biological Information
          Purity ≥98% by HPLC
          Physicochemical Information
          Solubility DMSO
          Dimensions
          Materials Information
          Toxicological Information
          Safety Information according to GHS
          Safety Information
          Product Usage Statements
          Storage and Shipping Information
          Ship Code Ambient Temperature Only
          Toxicity Regulatory Review
          Storage +2°C to +8°C
          Protect from Light Protect from light
          Do not freeze No
          Special Instructions Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
          Packaging Information
          Packaged under inert gas Packaged under inert gas
          Transport Information
          Supplemental Information
          Specifications

          Documentation

          FDS

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          Certificats d'analyse

          TitreNuméro de lot
          567737

          Références bibliographiques

          Aperçu de la référence bibliographique
          Guerrero, M., et al. 2011. Bioorg. Med. Chem. Lett. 21, 3632.
          Fiche technique

          Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

          Revision 30-April-2012 JSW
          Synonyms CYM50358
          Description An arylcarboxamide that acts as a potent and selective sphingosine-1-phosphate receptor 4 (S1P4) antagonist (IC50 = 25 nM), among a panel of five S1P receptors. It is shown to inhibit other S1P isoforms only at much higher concentrations (IC50 = 6.4 µM, 3.9 µM, 5.5 µM, and 25 µM for S1P1, S1P2, S1P5, and S1P3 (95% inhibition), respectively).
          Form White solid
          Intert gas (Yes/No) Packaged under inert gas
          Molar mass 389.28
          Chemical formula C₂₀H₁₈Cl₂N₂O₂
          Structure formula
          Purity ≥98% by HPLC
          Solubility DMSO (100 mg/ml; clear, colorless solution)
          Storage +2°C to +8°C
          Protect from light
          Do Not Freeze No
          Special Instructions Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
          Toxicity Regulatory Review
          References Guerrero, M., et al. 2011. Bioorg. Med. Chem. Lett. 21, 3632.