Amino acids with their corresponding molecular weights (Da) before any post-translational modification.
Cell signaling pathways coordinate most cellular functions. Studying these pathways can be challenging, because the signaling proteins involved are typically numerous, transient, low in abundance, and affected by reversible post-translational modifications (PTMs). Modifications to histones and other nuclear proteins can regulate DNA transcription, repair, recombination, and replication, and can alter local chromatin architecture.
Detect Post-Translational Modifications
Merck’s technologies for signaling research, combined with validated antibodies for proteins and PTMs, enable you to choose the perfect assay to answer your specific research question: