205548 Caffeine - CAS 58-08-2 - Calbiochem

205548
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      Descripción

      Replacement Information

      Tabla espec. clave

      Empirical FormulaCAS #
      C₈H₁₀N₄O₂ 58-08-2

      Precios y disponibilidad

      Número de referenciaDisponiblidad Embalaje Cant./Env. Precio Cantidad
      US1205548-500GM
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          Frasco de vidrio 500 gm
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          Description
          OverviewTrimethylated xanthine that acts as a potent central nervous system stimulant. At higher doses, produces tachycardia and interferes with the uptake and storage of Ca2+ by the sarcoplasmic reticulum in skeletal muscle. Prevents apoptosis and cell cycle effects induced by Camptothecin (Cat. No. 208925) and topotecan in HL-60 cells.
          Catalogue Number205548
          Brand Family Calbiochem®
          Synonyms3,7-Dihydro-1,3,7-trimethyl-1H-purine-2,6-dione
          References
          ReferencesZhen, W., and Vaugha, A. T. 1995. Radiat. Res. 141, 170.
          Howell, L. L. 1993. Cancer Res. 54, 4993.
          Traganos, F., et al. 1993. Cancer Res. 53, 4613.
          Zahradnik, I., and Palade, P. 1993. Pflugers Arch. 424, 129.
          Product Information
          CAS number58-08-2
          ATP CompetitiveN
          FormWhite solid
          Hill FormulaC₈H₁₀N₄O₂
          Chemical formulaC₈H₁₀N₄O₂
          ReversibleN
          Structure formula ImageStructure formula Image
          Applications
          ApplicationCaffeine, CAS 58-08-2, is a trimethylated xanthine that acts as a potent central nervous system stimulant. At higher doses, produces tachycardia.
          Biological Information
          Primary TargetPotent central nervous system stimulant
          Purity≥99% by HPLC
          Physicochemical Information
          Cell permeableN
          Dimensions
          Materials Information
          Toxicological Information
          Safety Information according to GHS
          RTECSEV6475000
          Safety Information
          R PhraseR: 22;

          Product Usage Statements
          Storage and Shipping Information
          Ship Code Ambient Temperature Only
          Toxicity Harmful
          Storage +15°C to +30°C
          Do not freeze Ok to freeze
          Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
          Packaging Information
          Transport Information
          Supplemental Information
          Specifications

          Documentation

          Ficha datos de seguridad (MSDS)

          Título

          Ficha técnica de seguridad del material (MSDS) 

          Certificados de análisis

          CargoNúmero de lote
          205548

          Referencias bibliográficas

          Visión general referencias
          Zhen, W., and Vaugha, A. T. 1995. Radiat. Res. 141, 170.
          Howell, L. L. 1993. Cancer Res. 54, 4993.
          Traganos, F., et al. 1993. Cancer Res. 53, 4613.
          Zahradnik, I., and Palade, P. 1993. Pflugers Arch. 424, 129.

          Folleto

          Cargo
          Caspases and other Apoptosis Related Tools Brochure
          Tools and Tips for Analyzing Apoptosis
          Ficha técnica

          Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

          Revision23-March-2018 JSW
          Synonyms3,7-Dihydro-1,3,7-trimethyl-1H-purine-2,6-dione
          DescriptionTrimethylated xanthine that acts as a potent central nervous system stimulant. A nonselective phosphodiesterase inhibitor. At higher doses, produces tachycardia and interferes with the uptake and storage of Ca2+ by the sarcoplasmic reticulum in skeletal muscle. Prevents apoptosis and cell cycle effects induced by camptothecin and topotecan in HL-60 cells.
          FormWhite solid
          CAS number58-08-2
          RTECSEV6475000
          Chemical formulaC₈H₁₀N₄O₂
          Structure formulaStructure formula
          Purity≥99% by HPLC
          SolubilityChloroform (50 mg/ml)
          Storage +15°C to +30°C
          Do Not Freeze Ok to freeze
          Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
          Toxicity Harmful
          Merck USA index14, 1636
          ReferencesZhen, W., and Vaugha, A. T. 1995. Radiat. Res. 141, 170.
          Howell, L. L. 1993. Cancer Res. 54, 4993.
          Traganos, F., et al. 1993. Cancer Res. 53, 4613.
          Zahradnik, I., and Palade, P. 1993. Pflugers Arch. 424, 129.