220551 Chloramphenicol - CAS 56-75-7 - Calbiochem

220551
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      Descripción

      Replacement Information

      Tabla espec. clave

      Empirical FormulaCAS #
      C₁₁H₁₂Cl₂N₂O₅ 56-75-7

      Precios y disponibilidad

      Número de referenciaDisponiblidad Embalaje Cant./Env. Precio Cantidad
      US1220551-25GM
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          Ampolla de plást. 25 gm
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          Description
          OverviewSynthetic bacteriostatic antibiotic that inhibits the translation of RNA by blocking the peptidyltransferase reaction on ribosomes.
          Catalogue Number220551
          Brand Family Calbiochem®
          References
          ReferencesLech, K., and Brent, R. 1995. in Current Protocols in Mol. Biol. Vol. 1, (Ausubel, F.M., et al., Eds.) John Wiley & Sons, New York.
          Lu, J., and Jiang, C. 1993. Biochem. Biophys. Res. Commun. 196, 12.
          Saltarelli, M.J., et al. 1993. Virol. 197, 35.
          Holt, J.T. 1992. Ann. N.Y. Acad. Sci. 660, 88.
          Maniatis, T., et al. 1989. In Molecular Cloning, A Laboratory Manual, Second Edition. Cold Spring Harbor, NY, p. 1.6, A.6.
          Product Information
          CAS number56-75-7
          FormGrayish to off-white crystalline powder
          Hill FormulaC₁₁H₁₂Cl₂N₂O₅
          Chemical formulaC₁₁H₁₂Cl₂N₂O₅
          Structure formula ImageStructure formula Image
          Applications
          Biological Information
          Biological activityPotency: ≥970 µg/mg
          Primary Targettrasnslation of RNA
          Purity≥97% by Assay
          Physicochemical Information
          Dimensions
          Materials Information
          Toxicological Information
          Safety Information according to GHS
          RTECSAB6825000
          Safety Information
          Product Usage Statements
          Storage and Shipping Information
          Ship Code Ambient Temperature Only
          Storage +15°C to +30°C
          Do not freeze Ok to freeze
          Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 1 year at -20°C.
          Packaging Information
          Transport Information
          Supplemental Information
          Specifications

          Documentation

          Ficha datos de seguridad (MSDS)

          Título

          Ficha técnica de seguridad del material (MSDS) 

          Certificados de análisis

          CargoNúmero de lote
          220551

          Referencias bibliográficas

          Visión general referencias
          Lech, K., and Brent, R. 1995. in Current Protocols in Mol. Biol. Vol. 1, (Ausubel, F.M., et al., Eds.) John Wiley & Sons, New York.
          Lu, J., and Jiang, C. 1993. Biochem. Biophys. Res. Commun. 196, 12.
          Saltarelli, M.J., et al. 1993. Virol. 197, 35.
          Holt, J.T. 1992. Ann. N.Y. Acad. Sci. 660, 88.
          Maniatis, T., et al. 1989. In Molecular Cloning, A Laboratory Manual, Second Edition. Cold Spring Harbor, NY, p. 1.6, A.6.

          Folleto

          Cargo
          Antibiotics Profiler
          Bulk Product Guide
          Drugs for Selection of Genetic Markers Technical Bulletin
          Overnight Express Autoinduction Systems
          Ficha técnica

          Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

          Revision07-January-2014 JSW
          DescriptionSynthetic bacteriostatic antibiotic that inhibits the translation of RNA to protein by binding to the 50S ribosomal subunit, blocking the peptidyl transferase reaction. Chloramphenicol resistance is encoded by the resistance gene cat, whose product, chloramphenicol acetyltransferase, inactivates the antibiotic via acetylation. Typically used at 30-50 µg/ml for selection of chloramphenicol-resistant Escherichia coli.
          FormGrayish to off-white crystalline powder
          CAS number56-75-7
          RTECSAB6825000
          Chemical formulaC₁₁H₁₂Cl₂N₂O₅
          Structure formulaStructure formula
          Purity≥97% by Assay
          Biological activityPotency: ≥970 µg/mg
          SolubilityEthanol, Methanol (35 mg/ml), or H₂O (2.5 mg/ml)
          Storage +15°C to +30°C
          Do Not Freeze Ok to freeze
          Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 1 year at -20°C.
          Merck USA index14 2077
          ReferencesLech, K., and Brent, R. 1995. in Current Protocols in Mol. Biol. Vol. 1, (Ausubel, F.M., et al., Eds.) John Wiley & Sons, New York.
          Lu, J., and Jiang, C. 1993. Biochem. Biophys. Res. Commun. 196, 12.
          Saltarelli, M.J., et al. 1993. Virol. 197, 35.
          Holt, J.T. 1992. Ann. N.Y. Acad. Sci. 660, 88.
          Maniatis, T., et al. 1989. In Molecular Cloning, A Laboratory Manual, Second Edition. Cold Spring Harbor, NY, p. 1.6, A.6.

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          Categorías

          Life Science Research > Inhibitors and Biochemicals > Small Molecules & Inhibitors > Other Inhibitors of Biological Interest > Protein Synthesis Inhibitors
          Life Science Research > Inhibitors and Biochemicals > Biochemicals > Antibiotics > Antimicrobial Agents
          Life Science Research > Cell Culture and Systems > Antibiotics & Selection Agents