05-23-0301 | Atrial Natriuretic Factor 1-28, Rat

05-23-0301
  
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      Overview

      Replacement Information

      Key Spec Table

      Empirical FormulaCAS #
      C₁₂₈H₂₀₅N₄₅O₃₉S₂ 88898-17-3
      Description
      OverviewReduces the activity of Na+,K+-ATPase in rat kidney. Activator of neuronal guanylate cyclase. Suppresses the transcription of its own guanylyl cyclase-linked receptor.
      Catalogue Number05-23-0301
      Brand Family Calbiochem®
      SynonymsrANF, SLRRSSCFGGRIDRIGAQSGLGCNSFRY
      References
      ReferencesCao, L., et al. 1995. J. Biol. Chem. 270, 24891. Gorny, D., et al. 1994. J. Physiol. Pharmacol. 45, 173. Rambotti, M.G., et al. 1994. Brain Res. 644, 52. Spreca, A., et al. 1994. Histochem. J. 26, 778.
      Product Information
      CAS number88898-17-3
      FormWhite to off-white solid
      Hill FormulaC₁₂₈H₂₀₅N₄₅O₃₉S₂
      Chemical formulaC₁₂₈H₂₀₅N₄₅O₃₉S₂
      Hygroscopic Hygroscopic
      Sold on the basis of peptide contentY
      Applications
      Biological Information
      Purity≥97% by HPLC
      Physicochemical Information
      Peptide ContentY
      Peptide SequenceH-Ser-Leu-Arg-Arg-Ser-Ser-Cys⁷-Phe-Gly-Gly-Arg-Ile-Asp-Arg-Ile-Gly-Ala-Gln-Ser-Gly-Leu-Gly-Cys²³-Asn-Ser-Phe-Arg-Tyr-OH (disulfide bond: 7 → 23)
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Ambient Temperature Only
      Toxicity Standard Handling
      Storage -20°C
      Hygroscopic Hygroscopic
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
      Packaging Information
      Transport Information
      Supplemental Information
      Specifications

      Documentation

      MSDS

      Title

      Safety Data Sheet (SDS) 

      Certificates of Analysis

      TitleLot Number
      05-23-0301

      References

      Reference overview
      Cao, L., et al. 1995. J. Biol. Chem. 270, 24891. Gorny, D., et al. 1994. J. Physiol. Pharmacol. 45, 173. Rambotti, M.G., et al. 1994. Brain Res. 644, 52. Spreca, A., et al. 1994. Histochem. J. 26, 778.

      Brochure

      Title
      Nitric Oxide and Oxidative Stress Brochure
      Data Sheet

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision18-September-2008 RFH
      SynonymsrANF, SLRRSSCFGGRIDRIGAQSGLGCNSFRY
      DescriptionReduces the activity of Na+-K+-ATPase in rat kidney. Activator of neuronal guanylate cyclase. Suppresses the transcription of its own guanylyl cyclase-linked receptor.
      FormWhite to off-white solid
      CAS number88898-17-3
      Chemical formulaC₁₂₈H₂₀₅N₄₅O₃₉S₂
      Peptide SequenceH-Ser-Leu-Arg-Arg-Ser-Ser-Cys⁷-Phe-Gly-Gly-Arg-Ile-Asp-Arg-Ile-Gly-Ala-Gln-Ser-Gly-Leu-Gly-Cys²³-Asn-Ser-Phe-Arg-Tyr-OH (disulfide bond: 7 → 23)
      Purity≥97% by HPLC
      Solubility5% Acetic acid (1 mg/ml) or DMSO (5 mg/ml)
      Storage -20°C
      Hygroscopic
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
      Toxicity Standard Handling
      Merck USA index14, 1360
      ReferencesCao, L., et al. 1995. J. Biol. Chem. 270, 24891. Gorny, D., et al. 1994. J. Physiol. Pharmacol. 45, 173. Rambotti, M.G., et al. 1994. Brain Res. 644, 52. Spreca, A., et al. 1994. Histochem. J. 26, 778.