164606 | Aminopeptidase N/CD13 Inhibitor - Calbiochem

164606
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      Overview

      Replacement Information

      Key Spec Table

      Empirical Formula
      C₁₃H₂₂NO₃P

      Pricing & Availability

      Catalogue NumberAvailability Packaging Qty/Pack Price Quantity
      US1164606-10MG
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      In Stock 
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          Glass bottle 10 mg
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          Description
          OverviewAn alpha-aminoaralkylphosphonic acid ester that acts as an aminopeptidase N/CD13 inhibitor (IC50=1.1 µM). Cell growth is dose dependently inhibited by as much as ~36% and ~60% in PANC-1 and HT-1080 cells, respectively when 300 µM of compound 4d is co-treated with 30 µg/ml of TNF. When treated with compound 4d alone, cell growth is dose-dependently inhibited by as much as 26% and 36%, in the same cell lines, respectively.
          Catalogue Number164606
          Brand Family Calbiochem®
          Synonyms4-tert-butylphenyl hydrogen 1-aminopropylphosphonate
          References
          ReferencesGrzywa, R., et al. 2010. Bioorg. Med. Chem. 8, 2930.
          Product Information
          FormWhite solid
          Hill FormulaC₁₃H₂₂NO₃P
          Chemical formulaC₁₃H₂₂NO₃P
          Structure formula ImageStructure formula Image
          Applications
          Biological Information
          Purity≥95% by HPLC
          Physicochemical Information
          Dimensions
          Materials Information
          Toxicological Information
          Safety Information according to GHS
          Safety Information
          Product Usage Statements
          Storage and Shipping Information
          Ship Code Shipped with Blue Ice or with Dry Ice
          Toxicity Standard Handling
          Storage -20°C
          Do not freeze Ok to freeze
          Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
          Packaging Information
          Transport Information
          Supplemental Information
          Specifications

          Documentation

          Certificates of Analysis

          TitleLot Number
          164606

          References

          Reference overview
          Grzywa, R., et al. 2010. Bioorg. Med. Chem. 8, 2930.
          Data Sheet

          Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

          Revision16-April-2012 JSW
          Synonyms4-tert-butylphenyl hydrogen 1-aminopropylphosphonate
          DescriptionAn alpha-aminoaralkylphosphonic acid ester that acts as an aminopeptidase N/CD13 inhibitor (IC50=1.1 µM). Cell growth is dose dependently inhibited by as much as ~36% and ~60% in PANC-1 and HT-1080 cells, respectively when 300 µM of compound 4d is co-treated with 30 µg/ml of TNF. When treated with compound 4d alone, cell growth is dose-dependently inhibited by as much as 26% and 36%, in the same cell lines, respectively.
          FormWhite solid
          Chemical formulaC₁₃H₂₂NO₃P
          Structure formulaStructure formula
          Purity≥95% by HPLC
          Solubility0.1N NaOH (1 mg/ml). Only partially soluble at 1 mg/ml in DMSO or H₂O.
          Storage -20°C
          Do Not Freeze Ok to freeze
          Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
          Toxicity Standard Handling
          ReferencesGrzywa, R., et al. 2010. Bioorg. Med. Chem. 8, 2930.