203702 Brain Derived Neurotrophic Factor, Human, Recombinant, E. coli

203702
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      Overview

      Replacement Information

      Key Spec Table

      Purity
      ≥97% by HPLC

      Pricing & Availability

      Catalogue NumberAvailability Packaging Qty/Pack Price Quantity
      US1203702-10UG
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          Plastic ampoule 10 μg
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          US1203702-5UG
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          In Stock 
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              Plastic ampoule 5 μg
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              Description
              OverviewRecombinant, human brain drived neurotrophic factor expressed in E. coli. Promotes survival and growth of neurons. Structurally and functionally related to nerve growth factor. Its actions are mediated via the TrkB receptor.
              Catalogue Number203702
              Brand Family Calbiochem®
              SynonymsrhBDNF
              References
              ReferencesErickson, J.T., et al. 1996. J. Neurosci. 16, 5361.
              Leibrock, J., et al. 1989. Nature 341, 149.
              Product Information
              FormLyophilized
              Applications
              Biological Information
              Biological activitySupports survival of rat basal forebrain primary septal cultured neurons. Induces choline acetyltransferase (EC₅₀ = 50 ng/ml)
              Purity≥97% by HPLC
              Physicochemical Information
              Dimensions
              Materials Information
              Toxicological Information
              Safety Information according to GHS
              Safety Information
              Product Usage Statements
              Storage and Shipping Information
              Ship Code Ambient Temperature Only
              Toxicity Standard Handling
              Storage -20°C
              Protect from Moisture Protect from moisture
              Do not freeze Ok to freeze
              Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C. Avoid freeze/thaw cycles of solutions.
              Packaging Information
              Transport Information
              Supplemental Information
              Specifications

              Documentation

              Certificates of Analysis

              TitleLot Number
              203702

              References

              Reference overview
              Erickson, J.T., et al. 1996. J. Neurosci. 16, 5361.
              Leibrock, J., et al. 1989. Nature 341, 149.

              Brochure

              Title
              Growth Factors and Cytokines Technical Bulletin
              Data Sheet

              Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

              Revision13-February-2019 JSW
              SynonymsrhBDNF
              DescriptionRecombinant, human brain drived neurotrophic factor expressed in E. coli. Promotes survival and growth of neurons in the central nervous system. Sequence analysis indicates that brain derived neurotrophic factor is structurally and functionally related to nerve growth factor. mRNA for brain derived neurotrophic factor is found predominantly in the central nervous system, whereas mRNA for nerve growth factor is also found in many non-CNS tissues.
              FormLyophilized
              Purity≥97% by HPLC
              Biological activitySupports survival of rat basal forebrain primary septal cultured neurons. Induces choline acetyltransferase (EC₅₀ = 50 ng/ml)
              SolubilityReconstitute to a concentration of ≥10 µg/ml with sterile distilled H₂O or aqueous buffers. For more dilute solutions, add a stabilizing protein such as 0.1% BSA or HSA.
              Storage -20°C
              Protect from moisture
              Do Not Freeze Ok to freeze
              Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C. Avoid freeze/thaw cycles of solutions.
              Toxicity Standard Handling
              Merck USA index14, 6487
              ReferencesErickson, J.T., et al. 1996. J. Neurosci. 16, 5361.
              Leibrock, J., et al. 1989. Nature 341, 149.