165304 | D-(–)-2-Amino-5-phosphonopentanoic Acid - CAS 79055-68-8 - Calbiochem

165304
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      Overview

      Replacement Information

      Key Spec Table

      Empirical FormulaCAS #
      C₅H₁₂NO₅P79055-68-8

      Pricing & Availability

      Catalogue NumberAvailability Packaging Qty/Pack Price Quantity
      US1165304-5MG
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          Plastic ampoule 5 mg
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          Description
          OverviewActive enantiomer of DL-2-amino-5-phosphonopentanoic acid (AP5) that is a commonly used as a competitive NMDA receptor antagonist. Also inhibits the capsaicin-induced release of substance P from spinal cord.
          Catalogue Number165304
          Brand Family Calbiochem®
          SynonymsD-AP5, NMDA Antagonist II, APV, D-APV, 2-APV, D-2-amino-5-phosphonovalerate
          References
          ReferencesMalcangio, M., et al. 1998. Br. J. Pharmacol. 125, 1625.
          Schulte, M.K., et al. 1994. Brain Res. 649, 203.
          Davis, S., et al. 1992. J. Neurosci. 12, 21.
          Product Information
          CAS number79055-68-8
          ATP CompetitiveN
          FormWhite solid
          Hill FormulaC₅H₁₂NO₅P
          Chemical formulaC₅H₁₂NO₅P
          Hygroscopic Hygroscopic
          ReversibleN
          Structure formula ImageStructure formula Image
          Applications
          Biological Information
          Primary TargetNMDA receptor antagonist
          Purity≥97% by HPLC
          Physicochemical Information
          Cell permeableN
          Dimensions
          Materials Information
          Toxicological Information
          Safety Information according to GHS
          Safety Information
          R PhraseR: 36/37/38

          Irritating to eyes, respiratory system and skin.
          S PhraseS: 26-36

          In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
          Wear suitable protective clothing.
          Product Usage Statements
          Storage and Shipping Information
          Ship Code Ambient Temperature Only
          Toxicity Irritant
          Storage +2°C to +8°C
          Protect from Light Protect from light
          Hygroscopic Hygroscopic
          Do not freeze Ok to freeze
          Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
          Packaging Information
          Transport Information
          Supplemental Information
          Specifications

          Documentation

          Certificates of Analysis

          TitleLot Number
          165304

          References

          Reference overview
          Malcangio, M., et al. 1998. Br. J. Pharmacol. 125, 1625.
          Schulte, M.K., et al. 1994. Brain Res. 649, 203.
          Davis, S., et al. 1992. J. Neurosci. 12, 21.

          Brochure

          Title
          Pathways and Biomarkers of Glutamatergic Synapse Flyer
          Data Sheet

          Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

          Revision10-April-2008 RFH
          SynonymsD-AP5, NMDA Antagonist II, APV, D-APV, 2-APV, D-2-amino-5-phosphonovalerate
          DescriptionActive enantiomer of DL-2-amino-5-phosphonopentanoic acid (AP5) that is a commonly used competitive NMDA receptor antagonist.
          FormWhite solid
          CAS number79055-68-8
          Chemical formulaC₅H₁₂NO₅P
          Structure formulaStructure formula
          Purity≥97% by HPLC
          SolubilityDilute Aqueous Base (1 mg/ml) or H₂O (1 mg/ml)
          Storage +2°C to +8°C
          Hygroscopic
          Protect from light
          Do Not Freeze Ok to freeze
          Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
          Toxicity Irritant
          ReferencesMalcangio, M., et al. 1998. Br. J. Pharmacol. 125, 1625.
          Schulte, M.K., et al. 1994. Brain Res. 649, 203.
          Davis, S., et al. 1992. J. Neurosci. 12, 21.