05-23-3801 | Endothelin 3, Human and Rat - CAS 117399-93-6 - Calbiochem

05-23-3801
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      Overview

      Replacement Information

      Key Spec Table

      Empirical FormulaCAS #
      C₁₂₁H₁₆₈N₂₆O₃₃S₄117399-93-6

      Pricing & Availability

      Catalogue NumberAvailability Packaging Qty/Pack Price Quantity
      US105233801-0.5MG
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      In Stock 
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          Plastic ampoule .5 mg
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          Description
          OverviewAttenuates thrombin-evoked aggregation of human platelets. A potent stimulator of interleukin-6 production by endothelial cell lines. Reported to activate phospholipase C in fibroblasts expressing ETA receptors.
          Catalogue Number05-23-3801
          Brand Family Calbiochem®
          SynonymsET-3, CTCFTYKDKECVYYCHLDIIW
          References
          ReferencesGresser, O., et al. 1996. Biochem. Biophys. Res. Commun. 224, 169.
          Astarie-Dequeker, C., et al. 1995. Br. J. Pharmacol. 114, 524.
          Xin, X., et al. 1995. Endocrinology 136, 132.
          Brunner, F., et al. 1992. J. Mol. Cell. Cardiol. 24, 1291.
          Lamers, J.M., et al. 1992. Mol. Cell. Biochem. 116, 59.
          Product Information
          CAS number117399-93-6
          ATP CompetitiveN
          FormSolid
          FormulationSupplied as a trifluoroacetate salt. Sold on the basis of peptide content.
          Hill FormulaC₁₂₁H₁₆₈N₂₆O₃₃S₄
          Chemical formulaC₁₂₁H₁₆₈N₂₆O₃₃S₄
          ReversibleN
          Sold on the basis of peptide contentY
          Applications
          Biological Information
          Primary TargetStimulator of interleukin-6 production by endothelial cell lines
          Purity≥97% by HPLC
          Physicochemical Information
          Cell permeableN
          Peptide ContentY
          Peptide SequenceH-Cys¹-Thr-Cys³-Phe-Thr-Tyr-Lys-Asp-Lys-Glu-Cys¹¹-Val-Tyr-Tyr-Cys¹⁵-His-Leu-Asp-Ile-Ile-Trp-OH (disulfide bonds: 1 → 15; 3 → 11)
          Dimensions
          Materials Information
          Toxicological Information
          Safety Information according to GHS
          Safety Information
          Product Usage Statements
          Storage and Shipping Information
          Ship Code Ambient Temperature Only
          Storage -20°C
          Protect from Moisture Protect from moisture
          Do not freeze Ok to freeze
          Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 1 month at -20°C.
          Packaging Information
          Transport Information
          Supplemental Information
          Specifications

          Documentation

          Certificates of Analysis

          TitleLot Number
          05-23-3801

          References

          Reference overview
          Gresser, O., et al. 1996. Biochem. Biophys. Res. Commun. 224, 169.
          Astarie-Dequeker, C., et al. 1995. Br. J. Pharmacol. 114, 524.
          Xin, X., et al. 1995. Endocrinology 136, 132.
          Brunner, F., et al. 1992. J. Mol. Cell. Cardiol. 24, 1291.
          Lamers, J.M., et al. 1992. Mol. Cell. Biochem. 116, 59.
          Data Sheet

          Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

          Revision18-September-2008 RFH
          SynonymsET-3, CTCFTYKDKECVYYCHLDIIW
          DescriptionAttenuates thrombin-evoked aggregation of human platelets. A potent stimulator of interleukin-6 production by endothelial cell lines. Reported to activate phopholipase C in fibroblasts expressing ETA receptors.
          FormSolid
          FormulationSupplied as a trifluoroacetate salt. Sold on the basis of peptide content.
          CAS number117399-93-6
          Chemical formulaC₁₂₁H₁₆₈N₂₆O₃₃S₄
          Peptide SequenceH-Cys¹-Thr-Cys³-Phe-Thr-Tyr-Lys-Asp-Lys-Glu-Cys¹¹-Val-Tyr-Tyr-Cys¹⁵-His-Leu-Asp-Ile-Ile-Trp-OH (disulfide bonds: 1 → 15; 3 → 11)
          Purity≥97% by HPLC
          Solubility5% Acetic acid (0.5 mg/ml). Dissolve peptide initially at 8 mg/ml in 80% cold acetic acid, then dilute with cold water to 5% acetic acid and 0.5 mg/ml peptide.
          Storage -20°C
          Protect from moisture
          Do Not Freeze Ok to freeze
          Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 1 month at -20°C.
          ReferencesGresser, O., et al. 1996. Biochem. Biophys. Res. Commun. 224, 169.
          Astarie-Dequeker, C., et al. 1995. Br. J. Pharmacol. 114, 524.
          Xin, X., et al. 1995. Endocrinology 136, 132.
          Brunner, F., et al. 1992. J. Mol. Cell. Cardiol. 24, 1291.
          Lamers, J.M., et al. 1992. Mol. Cell. Biochem. 116, 59.