165350 | PARP Inhibitor I, 3-ABA - CAS 3544-24-9 - Calbiochem

165350
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      Overview

      Replacement Information

      Key Spec Table

      Empirical FormulaCAS #
      C₇H₈N₂O3544-24-9

      Pricing & Availability

      Catalogue NumberAvailability Packaging Qty/Pack Price Quantity
      US1165350-100MG
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          Plastic ampoule 100 mg
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          Description
          OverviewA cell-permeable anti-proliferative agent that acts as an inhibitor of poly(ADP-ribose) polymerase (PARP). Has minimal effect on bacterial toxin-mediated ADP-ribosylation. An inhibitor of UV-induced apoptosis. Also strongly inhibits K562 target cell killing by human effector natural killer cells.
          Catalogue Number165350
          Brand Family Calbiochem®
          Synonyms3-Aminobenzamide
          References
          ReferencesTiozzo, R., et al. 1996. Biochem. Biophys. Res. Commun. 225, 826.
          Malorni, W., et al. 1995. Biochem. Biophys. Res. Commun. 207, 715.
          Malorni, W., et al. 1994. Biochem. Biophys. Res. Commun. 199, 1250.
          Monti, D., et al. 1994. Biochem. Biophys. Res. Commun. 199, 525.
          Kozak, K.R., and Ross, I.A. 1991. Biochem. Biophys. Res. Commun. 179, 1225.
          Product Information
          CAS number3544-24-9
          ATP CompetitiveN
          FormWhite solid
          Hill FormulaC₇H₈N₂O
          Chemical formulaC₇H₈N₂O
          ReversibleN
          Structure formula ImageStructure formula Image
          Applications
          Biological Information
          Primary TargetPARP
          Purity≥99% by GC
          Physicochemical Information
          Cell permeableY
          Dimensions
          Materials Information
          Toxicological Information
          Safety Information according to GHS
          RTECSCU8992000
          Safety Information
          R PhraseR: 36/37/38

          Irritating to eyes, respiratory system and skin.
          S PhraseS: 26-36

          In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
          Wear suitable protective clothing.
          Product Usage Statements
          Storage and Shipping Information
          Ship Code Ambient Temperature Only
          Toxicity Irritant
          Storage +15°C to +30°C
          Do not freeze Ok to freeze
          Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C ). Stock solutions are stable for 3 months at -20°C.
          Packaging Information
          Transport Information
          Supplemental Information
          Specifications

          Documentation

          Certificates of Analysis

          TitleLot Number
          165350

          References

          Reference overview
          Tiozzo, R., et al. 1996. Biochem. Biophys. Res. Commun. 225, 826.
          Malorni, W., et al. 1995. Biochem. Biophys. Res. Commun. 207, 715.
          Malorni, W., et al. 1994. Biochem. Biophys. Res. Commun. 199, 1250.
          Monti, D., et al. 1994. Biochem. Biophys. Res. Commun. 199, 525.
          Kozak, K.R., and Ross, I.A. 1991. Biochem. Biophys. Res. Commun. 179, 1225.

          Brochure

          Title
          Caspases and other Apoptosis Related Tools Brochure
          Data Sheet

          Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

          Revision01-May-2014 JSW
          Synonyms3-Aminobenzamide
          DescriptionA cell-permeable anti-proliferative agent that acts as an inhibitor of poly(ADP-ribose) polymerase (PARP). Has minimal effect on bacterial toxin-mediated ADP-ribosylation. An inhibitor of UV-induced apoptosis. Also strongly inhibits K562 target cell killing by human effector natural killer cells.
          FormWhite solid
          CAS number3544-24-9
          RTECSCU8992000
          Chemical formulaC₇H₈N₂O
          Structure formulaStructure formula
          Purity≥99% by GC
          SolubilityDMSO (5 mg/ml), Ethanol (1 mg/ml), or H₂O (1 mg/ml)
          Storage +15°C to +30°C
          Do Not Freeze Ok to freeze
          Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C ). Stock solutions are stable for 3 months at -20°C.
          Toxicity Irritant
          ReferencesTiozzo, R., et al. 1996. Biochem. Biophys. Res. Commun. 225, 826.
          Malorni, W., et al. 1995. Biochem. Biophys. Res. Commun. 207, 715.
          Malorni, W., et al. 1994. Biochem. Biophys. Res. Commun. 199, 1250.
          Monti, D., et al. 1994. Biochem. Biophys. Res. Commun. 199, 525.
          Kozak, K.R., and Ross, I.A. 1991. Biochem. Biophys. Res. Commun. 179, 1225.