05-23-5501 Parathyroid Hormone 1-34, Human - CAS 52232-67-4 - Calbiochem

05-23-5501
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      Overview

      Replacement Information

      Key Spec Table

      Empirical FormulaCAS #
      C₁₈₁H₂₉₁N₅₅O₅₁S₂52232-67-4

      Pricing & Availability

      Catalogue NumberAvailability Packaging Qty/Pack Price Quantity
      US105235501-1MG
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          Plastic ampoule 1 mg
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          Description
          OverviewN-terminal active peptide fragment of the native hormone that functions as a regulatory factor in the homeostatic control of Ca2+ and phosphate metabolism. Regulates Ca2+ and phosphate flux across cellular membranes in bone and kidney, resulting in increased serum Ca2+ levels. Increases the activity of osteoblasts and osteoclasts. Increases tubular reabsorption of Ca2+ and stimulates renal hydroxylation of 25-(OH)-Vitamin D3 to 1,25-(OH)2-Vitamin D3. Increases the production of inhibitory IGF binding protein 4 in bone cells.
          Catalogue Number05-23-5501
          Brand Family Calbiochem®
          References
          ReferencesMatsui, H., et al. 1995. Am. J. Physiol. 268, R21.
          Dua, K., et al. 1994. Exp. Physiol. 79, 401.
          Product Information
          CAS number52232-67-4
          ATP CompetitiveN
          FormWhite to off-white lyophilized solid
          FormulationSupplied as an trifluoroacetate salt.
          Hill FormulaC₁₈₁H₂₉₁N₅₅O₅₁S₂
          Chemical formulaC₁₈₁H₂₉₁N₅₅O₅₁S₂
          ReversibleN
          Sold on the basis of peptide contentY
          Applications
          Biological Information
          Primary TargetHomeostatic control of Ca2+ and phosphate metabolism
          Purity≥95% by HPLC
          Physicochemical Information
          Cell permeableN
          Peptide ContentY
          Peptide SequenceH-Ser-Val-Ser-Glu-Ile-Gln-Leu-Met-His-Asn-Leu-Gly-Lys-His-Leu-Asn-Ser-Met-Glu-Arg-Val-Glu-Trp-Leu-Arg-Lys-Lys-Leu-Gln-Asp-Val-His-Asn-Phe-OH
          Dimensions
          Materials Information
          Toxicological Information
          Safety Information according to GHS
          Safety Information
          Product Usage Statements
          Storage and Shipping Information
          Ship Code Ambient Temperature Only
          Toxicity Standard Handling
          Storage -20°C
          Protect from Moisture Protect from moisture
          Do not freeze Ok to freeze
          Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
          Packaging Information
          Transport Information
          Supplemental Information
          Specifications

          Documentation

          Certificates of Analysis

          TitleLot Number
          05-23-5501

          References

          Reference overview
          Matsui, H., et al. 1995. Am. J. Physiol. 268, R21.
          Dua, K., et al. 1994. Exp. Physiol. 79, 401.
          Data Sheet

          Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

          Revision4-October-2018 JSW
          DescriptionN-terminal active peptide fragment of the native hormone that functions as a regulatory factor in the homeostatic control of Ca2+ and phosphate metabolism. Regulates Ca2+ and phosphate flux across cellular membranes in bone and kidney, resulting in increased serum Ca2+ levels. Increases the activity of osteoblasts and osteoclasts. Increases tubular reabsorption of Ca2+ and stimulates renal hydroxylation of 25-(OH)-Vitamin D3 to 1,25-(OH)2-Vitamin D3. Increases the production of inhibitory IGF binding protein 4 in bone cells.
          FormWhite to off-white lyophilized solid
          FormulationSupplied as an trifluoroacetate salt.
          CAS number52232-67-4
          Chemical formulaC₁₈₁H₂₉₁N₅₅O₅₁S₂
          Peptide SequenceH-Ser-Val-Ser-Glu-Ile-Gln-Leu-Met-His-Asn-Leu-Gly-Lys-His-Leu-Asn-Ser-Met-Glu-Arg-Val-Glu-Trp-Leu-Arg-Lys-Lys-Leu-Gln-Asp-Val-His-Asn-Phe-OH
          Purity≥95% by HPLC
          Solubility5% acetic acid (1 mg/ml)
          Storage -20°C
          Protect from moisture
          Do Not Freeze Ok to freeze
          Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
          Toxicity Standard Handling
          Merck USA index14, 7034
          ReferencesMatsui, H., et al. 1995. Am. J. Physiol. 268, R21.
          Dua, K., et al. 1994. Exp. Physiol. 79, 401.

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          Categories

          Life Science Research > Inhibitors and Biochemicals > Biochemicals > Hormones > Other Hormones