Columns for USP Specifications

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Merck offers a comprehensive range of high-quality HPLC columns. Among these are a wide selection of columns that meet USP (United States Pharmacopoeia) specifications. The L nomenclature was introduced by the USP to designate column types for high-performance liquid chromatography. To help you select the appropriate HPLC column for your application, the table below describes various L columns as well as the corresponding HPLC columns available from Merck.

USP
Description
Columns
L1 Octadecly silane (ODS or C18) chemically bonded to porous silica or ceramic particles, 1.5 to 10 µm in diameter Chromolith® RP-18 Endcapped
LiChrosorb® RP-18 (5 µm)
LiChrosorb® RP-18 (10 µm)
LiChrospher® RP-18 (5 µm)
LiChrospher® RP-18 (10 µm)
LiChrospher® RP-18 Endcapped (5 µm)
LiChrospher® RP-18 Endcapped (10 µm)
Purospher® RP-18 (5 µm)
Purospher® RP-18 Endcapped (5 µm)
Purospher® STAR RP-18 Endcapped (3 µm)
Purospher® STAR RP-18 Endcapped (5 µm)
Superspher® RP-18 Endcapped (4 µm)
Superspher® RP-18 (4 µm)
L3 Porous silica particles, 1.5 to 10 µm in diameter Chromolith® Si
LiChrosorb® Si 60 (5 µm)
LiChrospher® Si 100
LiChrospher® Si 60 (10 µm)
LiChrospher® Si 60 (5 µm)
Purospher® STAR Si (5 µm)
Superspher® Si 60 (4 µm)
L7 Octyl silane (C8) chemically bonded to porous silica particles, 1.5 to 10 µm in diameter Chromolith® RP-8 Endcapped
LiChrosorb® RP-8 (5 µm)
LiChrosorb® RP-8 (10 µm)
LiChrospher® RP-8 (5 µm)
LiChrospher® RP-8 (10 µm)
LiChrospher® RP-8 endcapped (5 µm)
LiChrospher® RP-Select B (5 µm)
LiChrospher® RP-Select B (10 µm)
Purospher® STAR RP-8 Endcapped (3 µm)
Purospher® STAR RP-8 Endcapped (5 µm)
Superspher® 60 RP-8 (4 µm)
Superspher® 60 RP-8 Endcapped (4 µm)
Superspher® 60 RP-Select B (4 µm)
L8 An essentially monomolecular layer of aminopropylsilane (NH2) chemically bonded to totally porous silica gel support, 3 to 10 µm in diameter LiChrospher® NH2 (10 µm)
Purospher® STAR NH2 (5 µm)
L10 Nitrile groups (CN) chemically bonded to porous silica particles, 3 to 10 µm in diameter LiChrospher® CN (10 µm)
LiChrospher® CN (5 µm)
L20 Dihydroxypropane groups chemically bonded to porous silica particles, 3 to 10 µm in diameter LiChrospher® Diol (5 µm)
LiChrosorb® Diol (5 µm)  
L29 Gamma alumina, reversed-phase, low carbon percentage by weight alumina-based polybutadiene spherical particles, 5 µm in diameter with a pore diameter of 80Å Aluspher® RP-select B
L45 Beta cyclodextrin bonded to porous silica particles, 5 to 10 µm in diameter ChiraDex® (5 µm)
 
 
 
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