Human Neural Stem Cell Lines

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ReNcell® VM and ReNcell® CX Cell Lines
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ReNcell® VM and ReNcell® CX are two well-established neural stem cell lines derived from developing human brains. ReNcell® VM and CX cells are generated from the ventral mesencephalon (VM) and cortical (CX) regions of the brain, respectively, and transduced with the myc transcription factor. Both cell lines offer phenotype and genotype stability, in addition to the multipotential neuronal differentiation capacity, over long-term culture.
The use of neural stem cells in medicine and research is becoming increasingly popular. Breakthrough studies have recently rejected the longstanding belief that neuronal tissue is incapable of regeneration. The discovery that neurons, astrocytes, and oligodendrocytes arise from neural stem cells located in specific regions of the brain reveals important clinical applications for treating central nervous system diseases, including Parkinson's disease, Alzheimer’s, and spinal cord repair.

Merck offers ready to use Neural Stem Cells derived from a variety of different sources. These products include novel stem cell lines derived from both adult, embryonic neural tissue and iPS cells. Cells are provided with optimized serum-free expansion and differentiation media along with a complete selection of antibodies and kits to characterize both neural stem cells and differentiated progeny.

ReNcell®

Consistent and dependable neural stem cell culture. ReNcell® neural progenitor cells are isolated from human fetal tissue and are immortalized to produce a robust and consistent NSC culture.
Featured Product
Human Oligodendrocytes
Product Highlight: Human Oligodendrocytes
Conveniently and efficiently generate enriched populations of human oligodendrocytes. This kit contains well- characterized human oligodendrocyte progenitor cells (OPCs) and media to expand and differentiate these cells into enriched populations of mature oligodendrocytes in only two to three weeks.

ENStem-A™

Ready to use human embryonic stem derived neural progenitors suitable for studies of early neurogenesis and development.

Human iPS Derived Neural Progenitors

Human iPS Derived Neural Progenitors- Skip the lengthy iPS generation steps by using our ready to use expandable neural progenitors derived from STEMCCA generated human iPS Cells.

Human Oligodendrocyte Progenitors

Ready-to-use expandable human Oligodendrocyte progenitor cells derived from from H9 human embryonic stem cell line. Form mature human oligodendrocytes within 2 weeks using our optimized cells and medium.